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Traditional Chinese medicine composition atomized liquid for prevention and adjuvant therapy of respiratory diseases and application of traditional Chinese medicine composition atomized liquid

A technology of adjuvant therapy and composition, which is applied in the direction of respiratory diseases, drug combination, drug delivery, etc., can solve the problems of poor atomization inhalation effect and difficult atomization, and achieve the effect of rapid action, small side effects, small size and portability

Active Publication Date: 2022-06-07
湖南润农生态茶油有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention provides a traditional Chinese medicine composition for preventing and assisting the treatment of respiratory diseases in order to solve the problems of few products, difficult atomization and poor effect of atomization inhalation. Atomized liquid and application to promote better atomization of traditional Chinese medicine composition and release effective substances

Method used

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  • Traditional Chinese medicine composition atomized liquid for prevention and adjuvant therapy of respiratory diseases and application of traditional Chinese medicine composition atomized liquid
  • Traditional Chinese medicine composition atomized liquid for prevention and adjuvant therapy of respiratory diseases and application of traditional Chinese medicine composition atomized liquid
  • Traditional Chinese medicine composition atomized liquid for prevention and adjuvant therapy of respiratory diseases and application of traditional Chinese medicine composition atomized liquid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1 Chinese medicine composition product preparation

[0041] (1) Introduction to the flavor of traditional Chinese medicine composition

[0042] The traditional Chinese medicine composition is composed of the rhododendron grape, honeysuckle, white flower gentian, strong fragrant rhododendron and camellia oil. It has the functions of clearing away heat and detoxifying, relieving cough, resolving phlegm and relieving asthma. For the prevention and adjuvant treatment of sore throat, oral ulcers, as well as acute bronchitis, acute exacerbation of chronic bronchitis, chronic obstructive pulmonary disease, etc. In the prescription, Xiantohe grape has the functions of clearing away heat and removing dampness, treating dizziness and swelling of the eyes and sores on the mouth and tongue. Honeysuckle clears heat and detoxifies, disperses wind-heat, mainly treats carbuncle, swollen boils, sore throat, erysipelas, blood dysentery due to heat toxin, wind-heat cold, and ...

Embodiment 2

[0067] Example 2 Clinical application evaluation of traditional Chinese medicine composition nebulized liquid

[0068] Test sample: select the traditional Chinese medicine composition atomized liquid of formulas two, four, six, eight and ten prepared in Example 1. Subject requirements: 120 males, aged ≥ 40 years, with a smoking history of more than 10 years, and with cough, expectoration and dyspnea during activity, chronic pharyngitis and chronic bronchitis, communicate with the subjects before the test, on a voluntary basis. Experimental grouping: randomly divided into six groups, 20 cases in the control group, the subjects were not given the intervention of the traditional Chinese medicine composition, and the number and frequency of smoking were the same as before; 100 cases in the research group were divided into five groups, 20 cases in each group, respectively The traditional Chinese medicine composition atomized liquid of formulas two, four, six, eight and ten, the at...

Embodiment 3

[0070] The investigation of embodiment 3 Chinese medicine composition volatile oil extraction time

[0071] Get three parts of Rhododendron Rhododendron by weight of formula 2 (4 parts of Snake Radix, 2 parts of honeysuckle, 2 parts of white flower gentian, 2 parts of Rhododendron Rhododendron), and soak them in distilled water according to 6 times of the raw material quality respectively for 1 hour, The volatile oil was collected by steam distillation for 4, 6 and 8 hours, and the extracted amount and properties of the volatile oil were recorded. The results showed that after 6 hours of extraction, the volatile oil was basically completely extracted; after 8 hours of extraction, the color of the volatile oil deepened.

[0072] Table 2 Comparison of volatile oil extraction time in a kind of traditional Chinese medicine composition

[0073]

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Abstract

The invention discloses traditional Chinese medicine composition atomized liquid for prevention and adjuvant therapy of respiratory diseases and application. Active substances are effectively reserved through a volatile oil extraction technology and a step-by-step extraction and purification technology, the active substances and solvents such as medical glycerol and propylene glycol are matched to prepare a precursor for electronic atomization of the traditional Chinese medicine composition, and dry paste fine powder obtained after extraction and purification of the traditional Chinese medicine composition, a propylene glycol-glycerol mixed solution (80%-95%: 5%-20%) and tea oil are mixed according to the mass ratio of 1: 10: 0.1-0.5 and evenly mixed, so that the traditional Chinese medicine composition is prepared. The liquid is transparent and clear faint yellow liquid. The precursor of the electronic atomization plays a role in prevention and treatment by means of an electronic atomizer through a heating electronic atomization technology, and the traditional Chinese medicine composition atomized liquid can be used for prevention and adjuvant treatment of throat pain, oral ulcer, acute tracheitis, acute attack of chronic bronchitis, chronic obstructive pulmonary disease and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an atomized liquid of a traditional Chinese medicine composition for preventing and assisting the treatment of respiratory diseases and its application. Background technique [0002] In addition to the two main routes of oral and skin administration, traditional Chinese medicine also has various routes such as inhalation, sublingual administration, rectal administration, nasal administration, vaginal administration, subcutaneous injection, intramuscular injection, acupoint injection and intravenous injection. , its absorption rate is arranged in order from low to high: skin administration, mucosal surface administration, intrarectal administration, oral administration, sublingual administration, subcutaneous injection administration, intramuscular injection administration, inhalation administration , Intravenous administration. Among them, compared with intr...

Claims

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Application Information

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IPC IPC(8): A61K9/72A61K9/12A61K36/87A61K36/88A61K47/10A61P11/00A61P11/04A61P29/00A61P1/02
CPCA61K9/12A61K9/0078A61K36/87A61K36/355A61K36/515A61K36/45A61K36/82A61K36/88A61K47/10A61P11/00A61P11/04A61P29/00A61P1/02A61K2236/331A61K2236/51A61K2236/53A61K2300/00Y02A50/30
Inventor 李顺祥李娟田海林唐婷陈晨倪晓婷
Owner 湖南润农生态茶油有限公司
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