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Adhesive tape agent

A tape and gel technology, applied in bandages, pharmaceutical formulations, medical science, etc., can solve the problems of adhesive residue, insufficient stimulation suppression, and exudation, and achieve the effect of improving release and inhibiting skin irritation

Pending Publication Date: 2022-08-02
NICHIBAN KK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, tapes are generally thin and have high adhesion (adhesiveness) to the skin, but there is a problem that the adhesive (paste) overflows, or the adhesive remains on the skin when it is peeled off, and when using a fabric In the case of a support having stretchability and air permeability, the components constituting the adhesive layer seep out from the surface of the support
In addition, there are various problems as follows: if the adhesive layers are attached to each other before sticking, it is difficult to peel off and become unusable; It is easy to peel off from the skin if you sweat when you sweat; it is accompanied by pain when peeling; it is difficult to peel off the release liner from the adhesive layer during use, etc.
However, in the previous proposals, stimulation inhibition was insufficient, or the stimulation effect of a specific drug was only suppressed
[0007] Furthermore, as a technique for continuously releasing (absorbing) an active ingredient into the skin, a liquid storage tape is known in which a support, a drug layer (containing the active ingredient) and a control layer (containing an adhesive) are laminated (Patent Document 15 ), but due to the multi-layer structure, there is a problem of cumbersome and complicated manufacturing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0134] Although an Example is shown below and this invention is demonstrated concretely, this invention is not limited to these Examples.

[0135] [Manufacture of adhesive tape (1)]

example 1

[0137] Dextrin palmitate (RheopearlKL2, Chiba Milling Co., Ltd.) was dissolved in (80-100°C, 150rpm, 10min) liquid paraffin (HICALLM) in a high-speed rotary mixer according to the compounding amount described in Table 1. -352, Kaneda Co., Ltd.). Moreover, the same operation was performed except that dextrin palmitate was not added about Example 6 which did not mix|blend dextrin fatty acid ester (henceforth a gelling agent), such as dextrin palmitate.

[0138] After the dextrin palmitate is dissolved, add methyl salicylate (Methyl salicylate from Japanese pharmacy), l-menthol (Japanese pharmacy l-menthol), dl-camphor (Japanese pharmacy dl-camphor), nonanoic acid Vanillamide (vanillamide pelargonate), styrene-isoprene-styrene block copolymer (the following SIS) (SIS5002: JSR Co., Ltd. and Quintac 3520: Nippon Zeon Co., Ltd.), terpene resin ( YS resin PX1150N; Yasuhara Chemical Co., Ltd.), hydrogenated rosin glyceride (Pinecrystal KE311: Arakawa Chemical Industry Co., Ltd.), and...

example 2

[0141] Except having changed the compounding quantity of dextrin palmitate into 0.5 mass %, it carried out similarly to Example 1, and obtained the adhesive tape which contained the packaging material.

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PUM

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Abstract

[Problem] To provide a novel adhesive tape agent capable of comprehensively solving various problems that an adhesive remains on the skin when spilling or peeling occurs, and when a stretchable and breathable support such as a fabric is used, components contained in an adhesive layer seep from the surface of the support. If the adhesive layers adhere to each other before adhesion, the adhesive layers are difficult to peel off and become unusable, or once the adhesive layers are peeled off from an adhesion site during adhesion, the adhesive layers are difficult to re-adhere, the adhesive layers are easy to peel off from the skin if sweating during adhesion, pain is caused during peeling, and the lining is difficult to peel off during use. In order to achieve sustained release (absorbability) of an active ingredient to the skin, there is a need for a complicated production method or the like. [Solution] A tape agent which contains a dextrin fatty acid ester and / or an inulin fatty acid ester in a pressure-sensitive adhesive layer (excluding a tape agent containing particles having a core-shell structure in which an active ingredient is contained in a core part and a surfactant is contained in a shell part).

Description

technical field [0001] The present invention relates to an adhesive tape agent without a core-shell structure, wherein 1) bleed-out of an adhesive is suppressed even when a support such as a fabric is used which has stretchability and air permeability; 2) the adhesiveness before sticking is improved Peelability of the adhesive layers and re-adhesion after peeling; 3) Improve adhesiveness when sweating during sticking; 4) Suppress skin irritation during sticking and pain during peeling; 5) Improve usability , especially the liner peel force. Background technique [0002] Patches are classified into tapes (non-aqueous patches) and poultices (aqueous patches). Among them, adhesive tapes are generally thin and have high adhesion (adhesion) to the skin, but there are problems in that the adhesive (paste) overflows, or the adhesive remains on the skin when peeled off, and there are problems in the use of fabrics. In the case of a support having stretchability and air permeabilit...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K47/36A61L15/58
CPCA61K9/70A61K47/36A61K9/7038A61L15/28A61L15/58
Inventor 小池玲雄奈城户博隆大迫哲平金箱真
Owner NICHIBAN KK
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