Arginine-ketoprofen with antalgic and inflammation relieving actions and its preparing process
Patent Information
- Authority / Receiving Office
- CN Β· China
- Current Assignee / Owner
- CHENGDU SHENGNUO BIOTEC CO LTD
- Publication Date
- 2002-10-30
- Estimated Expiration
- Not applicable Β· inactive patent
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Abstract
Description
Technical field:
[0001] The present invention relates to a kind of arginine ketoprofen suitable for analgesia and anti-inflammatory and corresponding isomeric isomers and a preparation method. technical background:
[0002] Ketoprofen is a non-steroidal anti-inflammatory drug. Because its efficacy is better than that of ibuprofen, it has attracted widespread attention from pharmacologists and clinicians around the world. Rheumatoid arthritis, ankylosing spondylitis, gout, osteoarthritis, hemophilic arthritis, cervical and lumbar spondylosis and migraine, trauma and post-operative pain. Because ketoprofen is an organic acid drug, insoluble in water, it is mainly distributed in the stomach, small intestine and kidney after gastrointestinal administration, so it has a great stimulating effect on the gastrointestinal tract, and the main clinical side effects are stomach pain and heartburn. Symptoms, nausea, vomiting, diarrhea, constipation, loss of appetite, weakness, etc., and...