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Adhesive bandage containing chitosan and collagen

A band-aid, chitosan technology, applied in medical science, absorbent pads, sheet delivery, etc., can solve the problems of poor compliance, elasticity, poor adhesion, etc., and achieve good permeability, low cost, and convenient use.

Inactive Publication Date: 2002-11-27
苗九昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, poor early adhesion, poor compliance and elasticity are its disadvantages

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Weigh 1kg of chitosan and 1kg of gelatin and dissolve in 0.05M acetic acid to 2% (W / V), add 0.01kg of glyceryl monostearate and stir evenly, grind the solution into a uniform liquid with a colloid mill, and add 0.05% acetic acid to wash Add 1kg of Bitel to adjust the pH of the solution to 5-7. Stir the solution at room temperature for 1 hour, then keep it at room temperature overnight to remove the remaining air bubbles in the solution in a dust-free atmosphere. The woven fabric is immersed in this homogeneous solution. Take out the non-woven fabric, irradiate it with the infrared lamp in the drying tunnel, and then dry it. The others are made with ordinary band-aids, and then packaged inside and outside, and sterilized by ethylene oxide irradiation before being put into storage.

Embodiment 2

[0015] Weigh 1 kg of chitosan and 1 kg of gelatin, dissolve in 0.05M acetic acid to 2% (W / V), add 0.01 kg of glyceryl monostearate and stir evenly, grind the solution into a uniform liquid with a colloid mill, and add 0.1% 6 -0.1 kg of aminocaproic acid, then add buffer to adjust the pH of the solution to 5-7, stir the solution at room temperature for 1 hour, and then keep it at room temperature overnight to remove the remaining bubbles in the solution in a dust-free atmosphere. 8.5kg of non-woven fabric is immersed in this homogeneous solution. Take out the non-woven fabric, irradiate it with the infrared lamp in the drying tunnel, and then dry it. The others are made with ordinary band-aids, and then packaged inside and outside, and sterilized by ethylene oxide irradiation before being put into storage.

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PUM

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Abstract

A composite biologic adhesive bandage is composed of pressure-sensitive adhesive hydroentangled cloth, hygroscopic pad, non-woven cloth, chitosan, I-type collagen and medicine preparation. Its advantages are high penetability, elasticity, flexibility, bioactivity and biodegradability, and low cost.

Description

Technical field [0001] The invention relates to a medical device dressing, in particular to a convenient and practical composite band-aid. Background technique [0002] Wound repair is one of the most important and basic problems faced by surgery and the entire medical profession. Experts predict that in the 21st century, the number of traumatized patients will increase exponentially. The demand for wound dressings will also face a new upsurge that continues to rise. Traditional dressings (gauze) are often attached to the wound surface due to blood coagulation. When the medicine is changed, the new granulation of the wound is repeatedly damaged, which prolongs the wound healing time and brings unbearable pain to the patient. With the rapid development of modern medicine, especially molecular biology, the concept of modern dressings has undergone a fundamental change, that is, dressings should not only cover wounds, but also have the function of promoting tissue repair, providing ...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61L15/32
Inventor 苗九昌傅筱冲张莉莉饶国厚
Owner 苗九昌
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