Disperse tablet contg. klinemycin hydrochloride palmitate, and its prepn. method
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 重庆凯林制药有限公司
- Publication Date
- 2005-01-05
- Estimated Expiration
- Not applicable · inactive patent
Abstract
Description
technical field
[0001] The invention relates to a clindamycin hydrochloride palmitate dispersible tablet and a preparation method thereof. Background technique
[0002] Clindamycin palmitate hydrochloride is a prodrug of clindamycin. Clindamycin has a higher antibacterial effect, which is 2-8 times that of lincomycin. Clindamycin mainly has a strong antibacterial effect on Gram-positive bacteria and various anaerobic bacteria. Its pharmacological research shows that free clindamycin is quickly hydrolyzed, and it is completely absorbed orally and has high bioavailability. It is suitable for a wide range of patients. Because this product has high oral bioavailability and is not affected by food, it is often made into an oral dosage form. However, so far, the oral dosage form at home and abroad is single, only granules, which cannot meet the needs of patients of all ages. Moreover, granules are easy to absorb moisture and deteriorate easily. Contents of the invention [0...