Cefixime pharmaceutical composition for injection

A drug compound, cefixime technology, applied in the directions of drug delivery, antibacterial drugs, pharmaceutical formulations, etc., can solve the problems of cefixime cannot be directly made into injections, low bioavailability of oral preparations, and gastrointestinal adverse reactions. , to achieve the effect of low cost, low toxicity, and reduced toxic and side effects
CN1593423AInactive Publication Date: 2005-03-16余安国
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
余安国
Publication Date
2005-03-16
Estimated Expiration
Not applicable · inactive patent
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Abstract

The invention discloses a cefixime pharmaceutical composition for injection, which is prepared from active component cefixime and solubility promoter by the weight proportion of 1-15 : 1 thus fully mixing in asepsis environment, the solubility promoter is selected from alkaline amino acids, alkali metals, or the inorganic or organic acid salt of alkaline-earth metals.
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Description

Technical field:

[0001] The invention relates to a drug compound of cephalosporin antibiotics, in particular to the third-generation cephalosporin antibiotic cefixime as an active ingredient, basic amino acids, inorganic or organic acid salts of alkali metals or alkaline earth metals as auxiliary components. Solvent, prepared drug compound for injection. Background technique:

[0002] The antibiotic cefixime (Cefixime, C 16 h 15 N 5 o 7 S 2 ) is a third-generation oral cephalosporin antibiotic. Cefixime has a strong affinity for target enzymes and high stability for β-lactamase. Cefixime has a broad-spectrum antibacterial effect on Gram-positive and Gram-negative bacteria, especially influenzae (such as: Streptococcus pneumoniae, Streptococcus epidermidis), pneumococcus and Gram-negative bacteria among Gram-positive bacteria Haemophilus influenzae, Moraxella, Catarella, Proteus mirabilis, Neisseria gonorrhoeae, Branhamella catarrhalis, Escherichia coli, Klebsiella, Se...

Claims

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