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Medicine for treating low myeloproliferative diseases and its preparing method

A disease and bone marrow technology, applied in the field of preparation of the drug, can solve problems such as no effect, inconvenient use for patients, and limited clinical application due to economic reasons, so as to reduce complications, improve cure rate and quality of life

Active Publication Date: 2005-10-12
陕西郝其军制药有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] (1) Raising white blood cells, the effect is rapid and the curative effect is certain, but it has no effect on erythroid and megakaryocytes
[0005] (2), injection medication, inconvenient for patients to use
[0006] (3), expensive, clinical application is limited by economic reasons
[0007] (4) For biological agents, allergies, bone / muscle pain, rash, fever, runny nose or chills often occur

Method used

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  • Medicine for treating low myeloproliferative diseases and its preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0134] Weigh the raw materials according to the following ratio:

[0135] Soap alum 100g American ginseng 80g hippocampus 60g

[0136] Cinnamon 40g Jujube 30g Walnut 40g

[0137] It is made into the processing steps of the preparation method of pill as follows:

[0138] (1), dry hippocampus and jujube at 75-80°C, pulverize them into fine powder of 80-120 mesh, set aside;

[0139] (2), smash the walnut kernels, and grind them into 80-120 mesh fine powder with soap alum, American ginseng, and cinnamon, and set aside;

[0140] (3), after placing the fine powder in step (1) and step (2) in the mixer and mixing them, use Co 60 radiation sterilization;

[0141] (4), put the honey in the interlayer pot, heat it with steam, and the temperature of refining honey is 116°C;

[0142] (5), combine the refined honey of step (4) and the fine powder prepared by step (3) in a weight ratio of 1:0.5-0.6, make pills from the reconciled pills, dry, plain pills, and pack activated carbon Clot...

Embodiment 2

[0144] Weigh the raw materials according to the following ratio:

[0145]Soap alum 100g American ginseng 60g hippocampus 40g

[0146] Cinnamon 50g Jujube 30g Walnut 50g

[0147] It is made into the processing steps of the preparation method of tablet as follows:

[0148] (1), dry hippocampus and jujube at 75-80°C, pulverize them into fine powder of 80-120 mesh, set aside;

[0149] (2), smash the walnut kernels, and grind them into 80-120 mesh fine powder with soap alum, American ginseng, and cinnamon, and set aside;

[0150] (3), after placing the fine powder in step (1) and step (2) in the mixer and mixing them, use Co 60 radiation sterilization;

[0151] (4), adding the sterilized medicinal powder and dextrin into the mixer in a weight ratio of 5:1, and mix evenly;

[0152] (5) Add 70% ethanol to the mixed material, granulate with a granulator, and compress into tablets.

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Abstract

The invention relates to a medicine for treating bone marrow hypoplasia diseases and a preparation method thereof. All kinds of bone marrow hematopoietic dysfunction and disorders, such as aplastic anemia, myelodysplastic syndrome, thrombocytopenia and other hematopoietic abnormalities are blood difficult diseases; , the effect is rapid and the curative effect is sure, but it has no effect on the erythroid and megakaryocyte lines. The invention is composed of soap alum, American ginseng, hippocampus, cinnamon, jujube and walnut kernel. The function is to warm the kidney and strengthen the marrow, nourish qi and nourish yin, generate blood and stop bleeding. It is used for aplastic anemia, leukopenia, thrombocytopenia, myelodysplastic syndrome, bone marrow injury caused by radiotherapy and chemotherapy, and thrombocytopenia. For patients with both qi and blood deficiency syndrome, it can promote the generation and differentiation of hematopoietic stem cells of granulocyte, erythroid and megakaryocyte, and has a stable effect on the treatment of bone marrow hypoproliferative diseases and the reduction of three lineage cells caused by radiotherapy and chemotherapy.

Description

Technical field: [0001] The invention relates to a medicine for treating bone marrow hypoplasia diseases, specifically a Chinese patent medicine prepared from traditional Chinese medicines, and also relates to a preparation method of the medicine. technical background: [0002] Various bone marrow hematopoietic dysfunction and disorder diseases, such as aplastic anemia, myelodysplastic syndrome (MDS), thrombocytopenia and other hematopoietic dysfunction diseases are blood difficult diseases; for aplastic anemia, modern medicine uses bone marrow Transplantation and hematopoietic stem cell transplantation have opened up an effective way for the complete cure of this disease, but due to genetic factors, rejection makes the survival rate of transplanted bone marrow cells and hematopoietic stem cells extremely low, so most of the patients are still taking androgen. Treatment is the mainstay. However, for patients with chronic aplastic anemia who have a long course of disease and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K9/48A61P19/08
Inventor 郝其军
Owner 陕西郝其军制药有限责任公司