Production method of zhutaisu (pig's born vegetarian)

A production method and technology of pig placenta, which are applied in the directions of drug combination, digestive system, medical raw materials derived from mammals, etc., can solve problems such as unreported production methods of pig placenta, and achieve improved fluidity, guaranteed activity, and improved The effect of extraction efficiency

Inactive Publication Date: 2005-10-26
广州白云山拜迪生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no health food developed with pig embryos as the main raw material in the domestic health food market, and the production method of pig placenta has not been reported.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take fresh pig embryos (including placenta), wash them with pure water, and use an electric mixer to crush the embryos and placenta into a paste (porridge). Pass the sample through a 60-mesh sieve and collect the filtered sample. Add antioxidants (tea polyphenols (Victor powder) 0.02%, tertiary butyl hydroquinone TBHQ0.01%) and lyoprotectants (sodium alginate 0.5%, Tween-80 0.5%, mannitol 4% , alanine 1%, glycine 1.5%), carry out low-temperature high-pressure homogenization after. Homogenization conditions: pressure 40Kg / cm 2 , the processing speed is 40L / hr, the homogenate volume is controlled at 1L each time, the homogenate time is 5 minutes (depending on the homogenate flow rate and sample volume), and the temperature is controlled at 0°C. Divide the homogenized samples into freezing trays, the height of the samples should not exceed 5cm, and freeze-dry them in a vacuum freeze dryer. The freeze-drying conditions are: pre-cooling at -50° C. for 1 hour; vacuuming, w...

Embodiment 2

[0029] Take fresh pig embryos (including placenta), wash them with pure water, add crushed ice made of pure water, and use an electric mixer to crush the embryos and placenta into a paste (porridge) shape. Pass the sample through a 60-mesh sieve and collect the filtered sample. Add antioxidants (tea polyphenols (Victor powder) 0.02%, tertiary butyl hydroquinone TBHQ 0.005%) and lyoprotectants (sodium alginate 0.1%, Tween-80 0.01%, mannitol 2%, alanine 2%, glycine 1%), add crushed ice made of citrate buffer, and carry out low temperature and high pressure homogenization. Homogenization conditions: pressure 60Kg / cm 2 , the processing speed is 60L / hr, the homogenate volume is controlled at 5L each time, the homogenate time is 10 minutes (depending on the homogenate flow rate and sample volume), and the temperature is controlled at 4°C. Divide the homogenized samples into freezing trays, the height of the samples should not exceed 5cm, and freeze-dry them in a vacuum freeze drye...

Embodiment 3

[0032] The conventional animal embryo freezing-thawing process and the process of the present invention are used to produce 1 kg of pig embryos, and the recovery rate and activity of active ingredients are compared. Porcine placenta activity was detected by lymphocyte rosette activity. The detection method is as follows:

[0033] Peripheral blood mononuclear cells of healthy people were separated with lymphatic separation fluid according to conventional methods, stained with 1% trypan blue to detect cell viability (should be >95%) and counted cells. Adjust the cell number to 2 x 10 with calf serum 6 / mL. Take 200 μL of cell solution into test tubes, divide them into freeze-thaw control group and homogenate group, and add samples to the final concentration of (1×10 -2 mg / L) (the sample was diluted with cell culture medium and sterilized by filtration). Water bath at 37°C for 90 minutes; wash sheep red blood cells with normal saline, and adjust the number of cells to 2×10 8...

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PUM

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Abstract

A process for preparing pig placenta extract from pig placenta includes such steps as washing, pulverizing, adding protecting agent, low-temp high-pressure homogenizing, centrifugal treating, vacuum freeze drying, and superfine pulverizing.

Description

technical field [0001] The invention belongs to the field of production methods of health products, and relates to a production method of pig placenta. Background technique [0002] Placenta is a compound active ingredient derived from animal embryos and placenta. Placenta is rich in nucleic acids, polypeptides, and proteins, and has the effects of strengthening the brain, improving immunity, and beautifying the skin. [0003] At present, sheep placenta health food is common in the health food market at home and abroad. Due to the distant relationship between sheep and humans, the active ingredients of sheep fetus extract are not easy to be fully utilized by the human body. At the same time, domestic sheep farming and pastoral areas are mainly concentrated in Ningxia, Qinghai, Gansu, Inner Mongolia and other northwestern regions. The annual slaughter season is concentrated in autumn and winter, resulting in serious interference with the supply of raw materials due to facto...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/50
Inventor 黄明
Owner 广州白云山拜迪生物医药有限公司
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