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Food for improving clinical conditions capable of lowering the concentration of low-molecular weight nitrogen-containing compounds in blood

A nitrogen compound and low-molecular-weight technology, applied in medical preparations containing active ingredients, food preparation, application, etc., can solve problems such as heavy burden on patients

Inactive Publication Date: 2006-04-26
CHEIRON JAPAN CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, taking a large amount of adsorbents that may have side effects is a great burden on patients, and it is necessary to seek a solution that can reduce this burden.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] (Example 1) beverage

[0053] Table 1 below shows the composition examples of raw materials and the amount of solid content per 100 g of beverage when water is added thereto to make a beverage. A 100 g drink (product) is made by adding water.

[0054] raw material

The amount of solid content per 100g of beverage

polydextrose

pectin

fructose

Sodium citrate

Vitamin C

Vitamin B 1

Vitamin B 2

Vitamin B 6

Vitamin B 12

Niacinamide

folic acid

DHA

calcium trioxyphosphate

MgCl 2

Fe Mineral Yeast

Zn mineral yeast

Cu Mineral Yeast

Mn Mineral Yeast

Konjac powder or agar

Spices (apple, citrus, etc.)

fruit juices or extracts

Taste Improver

sweetener

~20g

~20g

~5g

~400mg

~500mg

~20mg

~20mg

~2mg

~1mg

~20mg

~5mg

~0.5g

~300mg

~200mg

~30mg

~50mg

~30mg

~10mg

A...

Embodiment 2

[0072] (embodiment 2) jelly-like food

[0073] Some composition examples of the jelly-like food material are shown in Table 2 below.

[0074] raw material

Mixing amount

apple juice dregs

pectin

polydextrose

Konjac mannan or agar

3~20g

1~10g

10~20g

0.1~2g

[0075] Add water to reach 60-105g.

[0076] About fructose, citric acid, sodium citrate, vitamin C, vitamin B (B 1 , B 2 , B 6 , Niacinamide, B 12 ), trace metals and mineral yeast, the situation (previous embodiment) of beverage and the situation (present embodiment) of jelly-like food are basically the same, so the raw material composition of jelly-like food is by 3 kinds shown in table 2 The raw materials below fructose shown in Table 1 were added to the raw materials to complete. Water was added to these raw materials and the water content was adjusted so that the total amount was 60 to 105 g.

[0077] The jelly-like food prepared by such a raw material ...

Embodiment 3

[0081] (Example 3) biscuit or cookie-like food

[0082] Dry or semi-dry foods in the form of cookies, biscuits, bread, or pancakes can be produced with indigestible polysaccharides as the main component. Composition examples of the raw materials are shown in Table 3 below.

[0083] raw material

%(dry weight)

polydextrose

apple juice dregs

pectin

Cellulose Fiber

Oligosaccharides

Starch (low gluten wheat flour)

cream (or shortening)

Other(*)

5～25％

10～40％

3～15％

5～10％

15～30％

5～20％

10～20％

1～10％

[0084] (*) According to Examples 1 and 2, 1 to 10% of sweeteners, spices, vitamins, and minerals

[0085] As indigestible polysaccharides, in addition to apple juice residue, water-soluble indigestible polysaccharides derived from seed coats of grains such as psyllium, soybean, and corn can be used, and spore-forming lactic acid bacteria preparations can also be added. (eg LACROSSE (registered...

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PUM

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Abstract

The object of the present invention is to provide a new improvement capable of preventing or delaying the transfer to hemodialysis therapy or reducing the number of implementations of the therapy in the case of renal dysfunction, and preventing or reducing the occurrence of hyperammonemia in the case of liver dysfunction Disease with food. In order to achieve this object, the disease-modifying food of the present invention is characterized by containing indigestible polysaccharides as the main component and limiting the addition of protein components. Thus, by using the energy generated by the absorption of indigestible polysaccharides, the urea or ammonia secreted into the intestines is used as the N source to synthesize bacterial protein, and the proliferated bacterial cells are excreted as feces to reduce the amount of nitrogen in the blood. Low-molecular nitrogen compounds, as a result, can improve renal dysfunction and liver dysfunction.

Description

technical field [0001] The present invention relates to a disease-improving food suitable for patients with renal dysfunction (or renal failure) or liver dysfunction (or liver failure). In more detail, it relates to the purpose of preventing or delaying the transfer to hemodialysis therapy in the case of renal dysfunction, or reducing the frequency of implementation of the therapy, and preventing or reducing the occurrence of hyperammonemia in the case of liver dysfunction And the food used to improve the condition. Background technique [0002] It is known that in humans and animals, dietary fiber or non-fibrous carbohydrates are not digested in the small intestine to increase excretion of nitrogen in feces. See, for example, Sealock, R.R., Basinski, D.H. & Murlin, J.R.: J. Nutrition, 22, 589-596 (1941); Mason, V.C. & Palmer, R.M.: Proc. Nutr. Soc., 32, 82A, 83A (1973); Weber, F.L. Gastroenterology: 77, 518-523 (1979) and Stephen, A., M. & Cummings, J.H.: Proc, Nutr. Soc....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A23L1/308A61P1/16A61P13/12
CPCA61K31/715A23L33/21A61P1/16A61P13/12
Inventor 弓狩康三小林隆明古谷修
Owner CHEIRON JAPAN CO
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