Use of elastic protease inhibitor for preparing medicine for protecting cerebral hemorrhage

An elastase and inhibitor technology is applied in the application field of elastase inhibitors in the preparation of cerebral hemorrhage protection drugs, and achieves the effects of high modeling success rate, good repeatability and easy positioning
CN1813706AInactive Publication Date: 2006-08-09CHONGQING PHARMA RES INST +1
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
CHONGQING PHARMA RES INST
Publication Date
2006-08-09
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to a new medicine application of elastic proteinase inhibitor, in the concrete, it relates to an application of neutral granulocyte elastic proteinase inhibitor sevilesta in preparation of medicine for preventing or / and curing cerebral hemorrhage. It can be freeze-dried powder injection and injection liquor.
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Description

technical field

[0001] The present invention relates to a new medical application of an elastase (neutrophil elastase, NE) inhibitor, and more specifically relates to the application of the neutrophil elastase inhibitor sivelestat in the preparation of a drug for preventing or / and treating cerebral hemorrhage. Background technique

[0002] Intracerebral hemorrhage (ICH) refers to non-traumatic intraparenchymal hemorrhage. After cerebral hemorrhage, in addition to the space-occupying damage of the hematoma itself, there are blood circulation disorders in the surrounding brain tissue, a decrease in the flow rate of local cerebral hemorrhage, metabolic disorders, Inflammatory reactions, etc., which lead to damage of surrounding cells and brain edema, resulting in neurological deficits.

[0003] Stroke is a common clinical emergency, mostly in middle-aged and elderly patients. With the aging of the population, the incidence of this disease is also increasing. Hemorrhagic stroke ...

Claims

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