Qi-invigorating constipation-relieving and preparation method thereof

A cataplasm and qi-promoting technology, which is applied in the field of preparation of cataplasm and matrix of Xingqi laxative plaster, which can solve problems such as allergies, small drug load, rash, etc., and achieve long-term drug release and strong sustained-release effect , the effect of moderate elasticity

Inactive Publication Date: 2006-12-13
张高红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional plasters (soft plasters, black plasters) are all based on fat-soluble materials, which have serious defects in application: small drug load, poor transdermal performance, allergies, rashes, hair sticking, clothing contamination, etc.
Catapults have been added under the general rules of preparations, but there are no varieties of poultices

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1: Formulation of cataplasm base

[0028] 1) Weighing: gelatin 0.440kg, polyvinyl alcohol 0.390kg, sodium carboxymethyl cellulose 0.210kg, castor oil 0.260kg, sodium polyacrylate 0.122kg, Tween-80 0.154kg, sorbic acid 0.009kg, kaolin 0.450kg , glycerol 0.660kg, tartaric acid 0.770kg, sorbitol 0.285kg, stomach soluble film coating powder 2.050kg, distilled water 4.200kg.

[0029] (2) Gelatin, polyvinyl alcohol and sodium carboxymethyl cellulose are respectively prepared into sols.

[0030] (3) Then add it into the container according to the weighing order, set the initial stirring speed at 100 rpm, and then increase the speed by 60 to 80 rpm each time a material is added, and stir for 6 to 9 minutes. After the feeding is completed, the stirring speed is increased to 1000-1200 rpm. The stirring is continued for 8-12 minutes to obtain the poultice matrix of the present invention.

Embodiment 2

[0031]Embodiment 2: the preparation of the medicament in the cataplasm

[0032] 1 Preparation of Xingqi laxative paste poultice extract:

[0033] (1) Weighing of traditional Chinese medicine: 2000g of ephedra, 2000g of white mustard seeds, 500g of kansui, 1000g of auspicious grass, 1500g of suzi, 1000g of asarum, 500g of columbine, and 1000g of dwarf tea.

[0034] (2) Extraction of extract, the above medicinal materials are selected, weighed, pulverized to 10-mesh coarse powder, put into a stainless steel container, and immersed for 8 hours by adding 1.8×8kg of 75-90% ethanol for the first time , and then transfer the soaked medicinal materials into a 300-500 liter stainless steel percolation barrel, add 75-90% ethanol for immersion for 50 hours, and sequentially add 4 × 8 kg of 75-90% ethanol, 4 × 8 kg of ethanol. 65~85% ethanol, 5×8kg 50~75% ethanol are percolated at a flow rate of 1.5ml / min per kilogram of medicinal materials, the ethanol is recovered by a spherical decomp...

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PUM

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Abstract

The invention relates to a bowel-relaxing cataplasm and its preparing process, which is mainly prepared from rhubarb horsetails 27-35%, fruit of citron or trifoliate orange 8-12%, magnolia bark 8-12 parts, banksia rose 8-12%, areca-nut 8-12%, Chinese angelica root 8-12%, astragalus root 8-12%, and fevervine 8-12%.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine patch and its preparation method using a matrix, in particular to a preparation method of a qi laxative patch for treating constipation, abdominal distention, postoperative intestinal flatulence and other diseases and a preparation method of the matrix. Background technique [0002] As we all know, plaster refers to a type of sheet-like external preparation made of medicinal extracts, medicinal materials or synthetic chemicals and suitable substrates for skin application, which can produce local or systemic effects. Includes rubber ointments, poultices, and patches. In the "Pharmacopoeia of the People's Republic of China 2000 Edition I" appendix to the general provisions of preparations, the balm ointment was added, but no balm varieties were included. [0003] Traditional plaster (ointment, black plaster) are all based on fat-soluble materials, and have serious defects in application: small drug...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K9/70A61P1/10
Inventor 张高红
Owner 张高红
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