Theapolyphenol composition and its preparation

A composition and technology of tea polyphenols, applied in the field of tea polyphenol composition and preparation thereof, can solve the problems of life danger, excitement, irritability, nausea, headache, insomnia and the like

Inactive Publication Date: 2007-04-04
INST OF PHARMACOLOGY & TOXICOLOGY ACAD OF MILITARY MEDICAL SCI P L A
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term, heavy drinking of caffeine can lead to addiction, which may cause excitement, irritability, nausea, headache, insomnia, etc., and even cause life-threatening

Method used

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  • Theapolyphenol composition and its preparation
  • Theapolyphenol composition and its preparation
  • Theapolyphenol composition and its preparation

Examples

Experimental program
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Effect test

Embodiment 1

[0051] Embodiment 1: Composition containing 90% tea polyphenol extract

[0052] The composition contains (percentage by weight) 90% of tea polyphenol extract, 7.5% of microcrystalline cellulose, 1.5% of magnesium stearate and 1% of sodium carboxymethyl cellulose. Among them, microcrystalline cellulose is also used as a binder and a disintegrating agent, and sodium carboxymethyl cellulose is a hygroscopic agent, which can chelate trace metal elements brought in during granulation and tabletting, and prevent metal elements from catalyzing tea polyphenols. Oxidation.

[0053] The dry granulation and tabletting process is adopted, and the lubricant is added twice during briquetting and tabletting. Pass the tea polyphenol extract and various auxiliary materials through an 80-mesh sieve, add the materials except magnesium stearate in order from less to more according to the equal volume incremental mixing method, and then add magnesium stearate and mix evenly. Press the above-ment...

Embodiment 2

[0058] Embodiment 2: Composition containing 73% tea polyphenol extract

[0059] The composition contains (percentage by weight) 73% of tea polyphenol extract, 25% of microcrystalline cellulose, 1% of magnesium stearate and 1% of sodium carboxymethyl cellulose. Among them, microcrystalline cellulose is also used as a binder and a disintegrating agent, pregelatinized starch is also used as a binder and a filler, and sodium carboxymethyl cellulose is a hygroscopic agent, and can be chelated in the process of granulation and tableting. The added trace metal elements prevent metal elements from catalyzing the oxidation of tea polyphenols.

[0060] Using powder direct compression technology,. Pass the tea polyphenol extract and various auxiliary materials through an 80-mesh sieve, add the materials except magnesium stearate in order from less to more according to the equal volume incremental mixing method, and then add magnesium stearate and mix evenly. Round tablets with a diamet...

Embodiment 3

[0065] Embodiment 3: Composition containing 70% tea polyphenol extract

[0066] Contain (weight percent) 70% tea polyphenol extract, 8% microcrystalline cellulose, 40% lactose, 1% magnesium stearate, 1% sodium carboxymethyl cellulose in the composition, use starch Paste as adhesive. Among them, microcrystalline cellulose is also used as a binder and a disintegrant, a lactose filler, and sodium carboxymethyl cellulose as a hygroscopic agent, and can chelate trace metal elements brought in during granulation and tableting to prevent metal elements from Catalyzes the oxidation of tea polyphenols.

[0067] Wet granulation tableting process is adopted. After the tea polyphenol extract and various auxiliary materials are passed through an 80-mesh sieve, each material except magnesium stearate is added in order from less to more according to the equal volume incremental mixing method and mixed evenly. Use 10% starch slurry as a binder to granulate, then dry and granulate to obtain...

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Abstract

A tea polyphenols composition for losing weight, improving immunity and antioxidizing power, decreasing blood fat, blood sugar and blood pressure, treating cancer and preventing the damage of irradiation, and its preparing process are disclosed.

Description

Technical field: [0001] The invention relates to a composition with tea polyphenol extract as the main raw material and its functions in weight loss, immunity enhancement, anti-oxidation, auxiliary blood fat reduction, blood sugar, blood pressure, auxiliary treatment of cancer, auxiliary protection against radiation hazards, etc. the use of. Background technique: [0002] In 1997, the World Health Organization (WHO) officially made it clear that obesity is a disease. And announced to the world: obesity will become the world's top health problem. According to the new point of view, obesity is not only regarded as excess body fat, but a chronic disease characterized by excess body fat, multi-cause, and can be combined with multiple diseases. Obesity may have adverse effects on every system of the body. The medical community has confirmed that cardiovascular and cerebrovascular diseases, which account for the highest human death rate in the world, and related diseases such a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61K36/82A61P3/04A61P3/06A61P3/10A61P9/12A61P35/00A61P37/04A61P39/06A61P43/00
Inventor 梅兴国连丽娜
Owner INST OF PHARMACOLOGY & TOXICOLOGY ACAD OF MILITARY MEDICAL SCI P L A
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