Disposable whole blood uric acid testing electrode indicator bar and manufacturing method thereof

A technology for detecting electrodes and blood uric acid, which is applied in the direction of measuring devices, electrical components, printed circuits, etc., can solve the problems of easy interference, unsuitable use, and expensive equipment of ascorbic acid, achieve the elimination of easily oxidized substances, improve accuracy and sensitivity, eliminate interference effect

Active Publication Date: 2007-04-25
桂林时云医疗科技有限公司
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

Its disadvantages are: ascorbic acid in blood samples is easy to interfere; samples must be deproteinized in advance; expensive equipment and professional analysts are required
Enzyme method is divided into enzyme-linked photometric method and enzyme-linked electrochemical method. The former is often used in automatic biochemical analyzers in hospitals and is suitable for the analysis of large quantities of samples. However, blood is separated into serum or plasma by centrifugation before analysis, requiring professional operators. and specialized reagents, not suitable for home use

Method used

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  • Disposable whole blood uric acid testing electrode indicator bar and manufacturing method thereof
  • Disposable whole blood uric acid testing electrode indicator bar and manufacturing method thereof
  • Disposable whole blood uric acid testing electrode indicator bar and manufacturing method thereof

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Embodiment Construction

[0017] Referring to Fig. 1 and Fig. 2, the present invention prints working electrode 2 and reference electrode 3 on an insulating substrate 1, and the lead-out wire (8,9) and contact (10,11) of working electrode 2 and reference electrode 3 , covering the insulating layer 12 on part of the electrodes (2, 3), wires (8, 9) and part of the contacts (10, 11), the reagent layer 4 on the working electrode 2 and the reference electrode 3, on the reagent layer Gasket 6 is pasted on the edge of 4, and the upper part is covered with a hydrophilic membrane 7, and the sample injection chamber 5 is surrounded by the reagent layer 4, gasket 6 and hydrophilic membrane 7.

[0018] In the present invention, the substrate 1 used to manufacture the test strip is any non-conductive and stable material. Suitable materials are polyester film, polyvinyl chloride and polycarbonate; any conductive material can be used for the substrate, wires and contacts, including silver, gold, platinum, carbon, and...

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Abstract

The invention relates to a one-time electrode detector for detecting uric acid in whole blood and its method of manufacture. The detector comprises insulated base (1), reference electrode (2), working electrode (3), reagent layer (4), sampling cavity (5). The reference electrode (2) and the working electrode (3) are carbon-coating which is silk-screened on the base (1); the reagent layer (4) consists of bovine serum albumin, electronic agency, agglomerant and pH buffer; the sampling cavity (5) is rounded by the reagent layer (4), shim (6) and hydrophilic film (7). The detector can effectively remove the interference of other compositions in blood and quickly and accurately detect the density of uric acid in whole blood; has the function of self-priming and automatic sampling, it is convenient to use; the method for making is simple, it is fit for mass production.

Description

technical field [0001] The invention relates to a disposable whole blood uric acid detection electrode test strip for detecting uric acid concentration in blood by electrochemical method and a manufacturing method. Background technique [0002] Uric acid (2,4,6-trihydroxypurine, referred to as UA) is the final product of purine metabolism in the human body, and has no physiological function in the human body. The main sources of purine in the human body are diet, nucleoprotein decomposition and de novo synthesis. Under normal circumstances, it is mainly excreted by the kidneys, and the rest is excreted from the body through the intestines, skin, and hair. Gout, hyperlipidemia, hematologic malignancy, psoriasis, kidney disease, chronic leukemia, multiple myeloma, monocytosis, polycythemia vera, etc. will all reflect elevated uric acid content clinically, while xanthine oxidation Reduced enzyme activity, Wilson's disease, hypoxanthine guanine ribosyltransferase deficiency, m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/327H05K1/00
Inventor 陈真诚柳建新赵于前
Owner 桂林时云医疗科技有限公司
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