Medicinal composition of baicalin, ganoderma lucidum and salvia miltrorrhiza
A composition and a technology of baicalin, which are applied in the field of medicine, have wide application prospects, remarkable curative effect, and improve the effect of anti-hepatitis activity.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0109] Example 1 Preparation of Ganoderma lucidum polysaccharide
[0110] Take Ganoderma lucidum, crush it into coarse grains, add 3 times the amount of water to moisten overnight, decoct three times the next day, add 12 times the amount of water for the first 3 hours, add 10 times the amount of water for the second 2 hours, add 10 times the amount of water for the third 1 hour Double the amount, combine the decoction, filter, concentrate the filtrate to a relative density of 1.02-1.06, let it cool, add ethanol to make the alcohol content 65%, stir well, place it at 4°C for 24 hours, filter, and recover the ethanol from the filtrate to No alcohol smell, filter, add ethanol to make the alcohol content 80%, stir well, place at 4°C for 24 hours, filter, recover the ethanol from the filtrate until there is no alcohol smell, place at 4°C for 48 hours, filter, concentrate the filtrate To thick paste, spray drying, that is.
[0111] Three batches of extracts were prepared respecti...
Embodiment 2
[0122] Example 2 Preparation of total phenolic acids of salvia miltiorrhiza
[0123] Take Salvia miltiorrhiza, crush it into coarse grains, add water and decoct three times, add 12 times the amount of water for the first 2 hours, add 10 times the amount of water for the second and third times each for 1.5 hours, combine the decoctions, filter, and concentrate the filtrate under reduced pressure to relative The density is 1.17-1.20 (80°C). Add ethanol for precipitation twice, the first time the alcohol content is 75%, the second time the alcohol content is 85%, each stand for 24 hours, recover the ethanol until the relative density is 1.17-1.20 (measured at 80°C), spray dry , that is.
[0124] identify
[0125] Take 0.2g of this product, grind it finely, add 25ml of 70% methanol, heat to reflux for 1 hour, filter, evaporate the filtrate to dryness, add 1ml of 70% methanol to dissolve the residue, and use it as the test solution. Take another salvianolic acid B reference subs...
Embodiment 3
[0138] Preparation of Example 3 HLD Composition Aqueous Injection
[0139] prescription:
[0140] Baicalin 250.0g
[0141] Ganoderma lucidum polysaccharide 97.2g (equivalent to 6kg of Ganoderma lucidum)
[0142] Total phenolic acid of salvia miltiorrhiza 300.0g (equivalent to 15kg of salvia miltiorrhiza)
[0143] Polysorbate 80 50g
[0144] Add water for injection to 1000ml
[0145]
[0146] A total of 1000 sticks were prepared
[0147] Note: The total content of main active ingredients in the total extract of traditional Chinese medicine is 61.9%.
[0148] Preparation Process:
[0149] 1) Dispose of the pipes and containers used for liquid preparation one day in advance, and rinse them with fresh water for injection before use.
[0150] 2) Add Ganoderma lucidum polysaccharide into water for injection with a dosing volume of 30%, heat and stir to dissolve completely. Add the total salvianolic acid and baicalin into a small amount ...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More