Gastroresistant Pharmaceutical Formulations Containing Rifaximin

a technology of rifaximin and rifaximin, which is applied in the direction of drug compositions, antibacterial agents, dispersed delivery, etc., can solve the problems of negative impact on use, side effects and unwanted risks of pharmacological interactions, and the absence of a placebo group in clinical trials, so as to facilitate ingestion, wide modulation of dosages, and modulation of dose strength
US20100330129A1Inactive Publication Date: 2010-12-30ALFA WASSERNANN SPA
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
ALFA WASSERNANN SPA
Publication Date
2010-12-30
Estimated Expiration
Not applicable · inactive patent

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Abstract

The object of the invention consists of pharmaceutical formulations containing rifaximin in the shape of microgranules made gastroresistant by an insoluble polymer at pH values between 1.5 and 4.0 and soluble at pH values between 5.0 and 7.5, by their preparation and by their use in the manufacture of medicinal preparations useful in the treatment of inflammatory bowel diseases (IBD) and mainly Crohn's disease.
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Description

[0001] This application is a continuation under 35 U.S.C. §120 of U.S. patent application Ser. No. 11 / 814,628, filed Jul. 24, 2007, which is a 35 U.S.C. §371 national phase filing of PCT Application No. PCT / EP2006 / 002022, filed Mar. 6, 2006, which claims priority to Italian Application No. BO 2005 A 000123, filed Mar. 7, 2005, the contents of each of which are hereby incorporated by reference.

[0002] The object of the invention consists of pharmaceutical formulations containing rifaximin in the shape of microgranules made gastroresistant by an insoluble polymer at pH values between 1.5 and 4.0 and soluble at pH values between 5.0 and 7.5, by their preparation and by their use in the manufacture of medicinal preparations useful in the treatment of inflammatory bowel diseases (IBD) and mainly Crohn's disease.BACKGROUND OF THE INVENTION

[0003] The intestinal apparatus is affected by many inflammatory diseases generally capped as inflammatory bowel diseases. In particular, Crohn's disease is...

Claims

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