Detection and prognosis of cervical cancer

a cervical cancer and prognosis technology, applied in the field of cervical cancer diagnosis and treatment, can solve the problems of limited reproducibility, low specificity of high-risk hpv testing for high-grade cervical neoplasia, and limitations of present pap test, and achieve accurate and effective early diagnostic assays.
US20110189653A1Inactive Publication Date: 2011-08-04MDXHEALTH
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
MDXHEALTH
Publication Date
2011-08-04
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to methods and kits for identifying, diagnosing, prognosing, and monitoring cervical cancer. These methods include determining the methylation status or the expression levels of particular genes, or a combination thereof.
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Description

FIELD OF THE INVENTION

[0001] The present invention relates to the area of cancer diagnostics and therapeutics. In particular, it relates to methods and kits for identifying, diagnosing, prognosing, and monitoring cervical cancer. These methods include determining the methylation status or the expression levels of particular genes, or a combination thereof.BACKGROUND TO THE INVENTION

[0002] Cervical cancer is the fifth most deadly cancer in women. Worldwide, approximately 500,000 cases of cervical cancer are diagnosed and about 250,000 women die from this disease annually (www.who.int / mediacentre / factsheets).

[0003] Most (80-90%) invasive cervical cancer develops in flat, scaly surface cells that line the cervix (called squamous cell carcinomas, SCC). Approximately 10-15% of cases develop in glandular surface cells (called adenocarcinomas, AdC). Less commonly, cervical cancers have features of both SCC and AdC. These are called adenosquamous carcinomas or mixed carcinomas (www.cancer.org)...

Claims

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