Apparatus and method for preconcentrating and transferring analytes from surfaces and measurement thereof using spectroscopy

a technology of surface analytes and spectroscopy, applied in the direction of instruments, separation processes, laboratory glassware, etc., can solve the problems of compromising mission operations, compromising positive identification, and major challenge in field measurement of suspected hazardous chemicals, so as to facilitate efficient and/or selective transfer of analytes

Inactive Publication Date: 2012-09-13
ORONO SPECTRAL SOLUTIONS
View PDF0 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0011]The present invention remedies the indicated problems associated with the prior art and serves as an enabling technology for currently fielded and future detection systems. In essence, the invention described herein can be considered ‘smart wipes’ that optimally capture and concentrate the unknown chemical onto a unique collection apparatus designed specifically so that it can either be: 1) analyzed directly by an analyzer without interferences or 2) manipulated so as to facilitate efficient and/or selective transfer of the analyte to a substrate for

Problems solved by technology

Field measurement of suspected hazardous chemicals is a major challenge in applied analytical chemistry.
While this instrument works well for some applications, if a suspect residue is not isolatable or is a thin coating, the instrument will not be presented with adequate sample amounts to make a positive identification, potentially compromising mission operations.
Furthermore, positive identification is compromised if the substance is on a surface that contains bands in the same region of the infrared spectrum that obscure the measurement.
In both of the above examples, adequate analysis of a trace residue on a surface would not be possible bec

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Apparatus and method for preconcentrating and transferring analytes from surfaces and measurement thereof using spectroscopy
  • Apparatus and method for preconcentrating and transferring analytes from surfaces and measurement thereof using spectroscopy
  • Apparatus and method for preconcentrating and transferring analytes from surfaces and measurement thereof using spectroscopy

Examples

Experimental program
Comparison scheme
Effect test

example 1

Silver Cyanide Detection in an Aqueous Residue on a Solid Surface Using Transmission and ATR Infrared Spectroscopy

[0055]In this example, an aqueous residue containing toxic silver cyanide was collected onto the collection substrate of the present invention and analyzed in 3 different ways using infrared spectroscopy to demonstrate several embodiments of the invention. The collection substrate was acquired from Orono Spectral Solutions, Inc. (OSS) of Bangor, Me. As used herein, “cyanide” refers to any chemical compound including a Carbon atom triple-bonded to a Nitrogen atom. It may be referred to herein from time to time as “CN.” Silver Cyanide may be referred to herein as AgCN.

[0056]Preparation of the AgCN Residue

[0057]AgCN residue was prepared by dissolving 100 mg of silver nitrate into 1 mL of deionized water. Once dissolved, 25 mg of sodium cyanide was added to the solution, which then turned cloudy as silver cyanide particles were formed. This slurry was then poured onto a labo...

example 2

Silver Phosphate Detection in an Aqueous Residue on a Solid Surface Using ATR Infrared Spectroscopy

[0068]In this example, an aqueous residue containing silver phosphate was collected onto the collection substrate of the present invention and analyzed in two different ways using infrared spectroscopy to demonstrate several embodiments of the invention. The collection substrate was acquired from OSS.

[0069]Preparation of the Silver Phosphate Residue

[0070]Silver phosphate residue was prepared by dissolving 200 mg of silver nitrate into 1 mL of deionized water. Once dissolved, 25 mg of sodium cyanide was added to the solution, which then turned cloudy as silver phosphate particles were formed. This slurry was then poured onto a laboratory bench, to generate an aqueous residue.

[0071]Collection of Silver Phosphate Residue Using OSS Collection Substrate

[0072]The residue was collected using OSS Collection Substrate (PN 092385) and a wiping motion to collect the residue. For this example, two...

example 3

Detection of Residue Containing BG Spores on Surfaces

[0079]In this example, a residue containing Bacillus globigii spores (BG) was collected onto the collection substrate of the present invention and analyzed using ATR infrared spectroscopy. The collection substrate was acquired from OSS.

[0080]Preparation of the BG Spore Residue

[0081]BG spore residue was prepared by applying a fine powder of BG spores on a steel surface.

[0082]Collection of BG Spore Residue Using OSS Collection Substrate

[0083]The residue was collected using OSS Collection Substrate (PN 04031982) and a wiping motion to collect the residue.

[0084]ATR FTIR Spectroscopy of OSS Collection Substrate

[0085]ATR FTIR spectroscopy (using a Bruker Alpha spectrometer outfitted with a Bruker Platinum ATR accessory) was used to measure BG spore residue collected on the OSS Collection Substrate (FIG. 10). The peaks near 1640 and 1560 cm−1 are due to amide bands from protein material in the spore. The peak near 1100 cm−1 is due to pol...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Transparencyaaaaaaaaaa
Hydrophobicityaaaaaaaaaa
Affinityaaaaaaaaaa
Login to view more

Abstract

A system and method for capturing a target analyte in advance of performing spectroscopic analysis to determine the existence of the target analyte from a source contacted with a collection substrate. The collection substrate is fabricated of a material selected to have an affinity for the target analyte, sufficiently transparent in a spectral region of interest and capable of immobilizing the target analyte thereon in a manner that limits scattering sufficient to obscure spectral analysis. The collection substrate may be coated with a material selected to react with, bind to, or absorb the target analyte. The method optionally includes the step of transferring the captured target analyte to a second substrate, which may be an optical substrate. The target analyte may be captured to the collection substrate by one or more of wiping, dabbing or swabbing a target analyte carrier with the collection substrate.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]The present application is a nonprovisional application, and claims the priority benefit of, U.S. provisional application Ser. No. 61 / 451,780, filed Mar. 11, 2011, entitled “Apparatus and Method for Preconcentrating and Transferring Analytes from Surfaces and Measurement Thereof Using Optical Spectroscopy,” and assignee to a common assignee, and the present application is also a nonprovisional application, and claims the priority benefit of, U.S. provisional application Ser. No. 61 / 522,593, filed Aug. 11, 2011, entitled “Apparatus and Method for Preconcentrating and Transferring Analytes from Surfaces and Measurement Thereof Using Spectroscopy,” and assignee to a common assignee. The entire contents of the priority applications are incorporated herein by reference.STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT[0002]This invention was made using funds obtained from the US Government (US Army, Contract No. W911SR-10-C-0064)...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G01N21/75G01N1/02B01L99/00B82Y15/00
CPCB01L3/5029G01N1/02G01N2021/3595G01N21/3563G01N21/552G01N2001/028G01N1/04G01N33/54373G01N2001/045
Inventor ROY, ERIC G.GETTINGS, RACHEL
Owner ORONO SPECTRAL SOLUTIONS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap