Synthetic biomaterial compound of calcium phosphate phases particularly adapted for supporting bone cell activity

a biomaterial and phase technology, applied in the direction of prosthesis, ceramics, other chemical processes, etc., can solve the problems of bloating performance in vivo, no prior composition developed, and no composition has been demonstrated to participate in the natural bone remodeling process
USRE41251E1Inactive Publication Date: 2010-04-20WARSAW ORTHOPEDIC INC
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Patents(United States)
Current Assignee / Owner
WARSAW ORTHOPEDIC INC
Publication Date
2010-04-20
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention is directed to a synthetic biomaterial compound based on stabilized calcium phosphates and more particularly to the molecular, structural and physical characterization of this compound. The compound comprises calcium, oxygen and phosphorous, wherein at least one of the elements is substituted with an element having an ionic radius of approximately 0.1 to 1.1 Å. The knowledge of the specific molecular and chemical properties of the compound allows for the development of several uses of the compound in various bone-related clinical conditions.
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Description

RELATED APPLICATIONS

[0001] This application is a continuation-in-part of copending U.S. patent application Ser. No. 09 / 029,872, filed Mar. 2,Jun. 29, 1998, which is a U.S. National Phase Application of PCT / CA96 / 00585, filed Aug. 30, 1996, which is a continuation-in-part of U.S. patent application Ser. No. 08 / 576,238, filed Dec. 21, 1995, now abandoned, which claims the benefit of U.S. Provisional Application Ser. No. 60 / 003,157, filed Sep. 1, 1995, which are each hereby incorporated herein in their entirety by reference. Application Ser. No. 09 / 044,749 claims priority to PCT Application No. PCT / CA98 / 00046, filed on Jan. 29, 1998.FIELD OF THE INVENTION

[0002] This invention is directed to a synthetic biomaterial compound based on stabilized calcium phosphates and more particularly to the molecular, structural and physical characterization of this compound. This compound which in the alternative may be referred to as Skelite,™ has applications in the treatment of various bone related cli...

Claims

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