15 results about "Vagina inflammation" patented technology

The invention discloses lactobacillus gasseri capable of improving expression of host antibacterial peptide Cathelicidin and secretory immunoglobulin sIgA and enhancing infection resistance by oral administration and external application and a metagen thereof, and belongs to the technical field of microorganisms. The lactobacillus gasseri disclosed by the invention can be used for promoting the generation of a vaginal epithelial cell antibacterial peptide Cathelicidin; the shedding of vaginal epithelial cells is reduced, the fungal load is reduced, and the generation of vaginal tissue antibacterial peptide CRAMP is improved; the pIgR and immune globulin content of the vaginal tissue is increased; the invention also finds that the lactobacillus gasseri for external use can regulate and control TLR2 (Toll-Like Receptor 2), and further has a good balancing effect on body immunity. Therefore, the lactobacillus gasseri has a huge application prospect in a product for improving the pathogenic bacterium infection resistance of a host, enhancing the self-defense capability and inhibiting the vagina inflammation.

The invention relates to a Fe3O4 (at) PDA-MnO2 nanometer material and a preparation method and application thereof, and belongs to the technical field of biological medicine, the Fe3O4 (at) PDA-MnO2 nanometer material shows excellent photo-thermal performance and peroxidase (POD) simulation activity, and the catalytic activity is enhanced under NIR irradiation. The Fe3O4 (at) PDA-MnO2 has a sterilization rate up to 99% and good biofilm formation destroying performance on gram-positive bacteria, gram-negative bacteria and gram-variant bacteria, in-vitro and BV mouse model experiments show that the Fe3O4 (at) PDA-MnO2 is combined with NIR irradiation, due to the synergistic antibacterial effect of the Fe3O4 (at) PDA-MnO2, vagina inflammation caused by bacterial infection of BV is remarkably reduced, and the Fe3O4 (at) PDA-MnO2 is superior to that of a positive control drug.

According to the probiotic composition and the application of the probiotic composition in preparation of products for preventing and treating vagina inflammation, the probiotic composition composed of lactobacillus gasseri B13.52 and lactobacillus mucus B14.46 screened from vaginal secretion of healthy women can effectively inhibit growth of escherichia coli, gardnerella and prevotella; the secretion of proinflammatory factors in vaginal epithelial cells can be obviously reduced, so that an anti-inflammatory effect is achieved.

The invention relates to the technical field of biological medicine, in particular to an external bacteriostatic anti-inflammatory anti-oxidation traditional Chinese medicine microecological preparation for vagina as well as a preparation method and application of the external bacteriostatic anti-inflammatory anti-oxidation traditional Chinese medicine microecological preparation. A preparation method of an external antibacterial, anti-inflammatory and antioxidant traditional Chinese medicine microecological preparation for vagina comprises the following steps: mixing traditional Chinese medicine powder, adding water and a nutrient substrate as a fermentation substrate, uniformly mixing, performing autoclaved sterilization, cooling, adding probiotic powder into the fermentation substrate, fermenting, air-drying and crushing, thereby obtaining the antibacterial, anti-inflammatory and antioxidant traditional Chinese medicine microecological preparation, the probiotics are lactobacillus plantarum; the traditional Chinese medicine is composed of cortex phellodendri, fructus cnidii, folium artemisiae argyi and liquorice. The traditional Chinese medicine composition can play a significant role in inhibiting bacteria, resisting inflammation, resisting oxidation and regulating flora, improves the vagina environment, and can be used for sterilizing, relieving itching, eliminating vagina inflammation, relieving skin oxidative injury and maintaining female vagina health.

The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating vagina inflammation and a preparation method and application thereof, the preparation method comprises the following steps: S1, preparing a prepared rehmannia root extract; s2, preparing a salted golden cypress extract and a salted rhizoma anemarrhenae extract; s3, preparing a radix paeoniae alba extract; s4, crushing tortoise-shell glue to obtain tortoise-shell glue powder; and S5, uniformly mixing the prepared rehmannia root extract, the salted golden cypress and rhizoma anemarrhenae extract, the white peony root extract and the tortoise-shell glue powder to obtain the traditional Chinese medicine composition. The traditional Chinese medicine composition prepared by a specific method on the basis of a formula of Guanhuang mother granules has a remarkable effect of improving vagina inflammation, and all the components have a synergistic effect, so that the vagina environment is improved, vagina epithelium repair is promoted, the local resistance of the vagina is enhanced, and the effect is remarkable.

The utility model relates to a multifunctional self-service nursing device for gynaecology internal vagina, and belongs to the technical field of daily supplies. Comprising a pushing and injecting device, the pushing and injecting device comprises a cylindrical barrel, a push rod arranged in the barrel and a rubber plug arranged at the top end of the push rod in a sleeving mode, a main body used for cleaning is arranged on the barrel, a plurality of prisms are arranged on the main body, water flow grooves are formed among the prisms, one ends of the prisms are arc-shaped heads, and one or more water outlet holes are formed in the prisms. Water inlets are formed in the ends, away from the arc-shaped head, of the multiple prisms, the water inlets communicate with the water outlet holes in the main body, the prisms are annularly and evenly distributed on the main body, and the output end of the barrel extends into the water inlets. The utility model provides a multifunctional self-service nursing device for gynaecology internal vagina, which can help women to realize professional internal vagina nursing at home and effectively prevent or treat gynaecology diseases such as internal vagina inflammation and the like.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition and traditional Chinese medicine gel for treating gynecological vaginitis and a preparation method thereof. The traditional Chinese medicine composition is prepared from sugarcane leaves, mango leaves, cinnamon leaves, citronella, gallnut, cortex phellodendri, rhizoma atractylodis, radix rubiae, fructus cnidii, pericarpium granati, radix sophorae flavescentis and alums. The traditional Chinese medicine gel comprises a traditional Chinese medicine composition and a gel matrix (Carbomer-940 and glycerol). The traditional Chinese medicine composition is subjected to water extraction and prepared into the gel, and the obtained traditional Chinese medicine gel has the effects of clearing away heat and drying dampness and killing parasites to relieve itching and is suitable for gynecological vagina inflammation, vulva infection and other symptoms. The traditional Chinese medicine composition can effectively prolong the duration of the medicine at the medication part, is beneficial to improving the medication compliance of a patient, can strengthen the treatment effect, and plays a key role in improving the compliance of the patient and enhancing the treatment effect of the medicine.

The invention discloses a Lactobacillus paracasei strain for regulating local secretory immune globulin and systemic immune globulin of a host to enhance infection resistance, and belongs to the technical field of microorganisms. The lactobacillus paracasei provided by the invention has the effects of reducing vaginal mucosa injury and inhibiting vagina inflammation, and the effects are specifically reflected as follows: (1) the expression of a polymeric immune globulin receptor gene of an organism is improved; (2) promoting the secretion of secretory immune globulin sIgA of the body; (3) promoting secretion of immune globulin IgG of the body; (4) reducing secretion of granulocyte colony stimulating factors of the body; (5) the secretion of TNF-alpha is inhibited, and the secretion of IL-10 is promoted; (6) improving pathological characterization of the organism; and (7) improving glycogen staining characterization after fungal infection of the organism. Therefore, the lactobacillus paracasei has a huge application prospect in products for improving vaginal mucosa injury and inhibiting vagina inflammation.

The antibacterial gel is prepared from the following substances in percentage by mass: 1% of carbomer, 1% of honeysuckle flower, 0.5% of astragalus polysaccharide, 2% of herba houttuyniae and the balance of purified water. The invention further discloses a method for preparing the antibacterial gel. According to the antibacterial gel prepared by the invention, the carbomer is used as a basis, the traditional Chinese medicine extract and the monoclonal antibody are combined, the components are simple, the preparation process is simple, and the finished gel has the advantages of safety, effectiveness and small use amount, and has a good curative effect on human papilloma virus (HPV) positive vagina inflammation and human papilloma virus (HPV) negative vagina inflammation.

The invention provides a traditional Chinese medicine composition for treating vaginitis as well as a preparation method and application of the traditional Chinese medicine composition. The composition is prepared from fructus cnidii, cortex dictamni, dried alum, cockscomb, borax, cortex phellodendri, fructus evodiae and herba leonuri. The composition provided by the invention can significantly inhibit vaginal harmful bacteria, protect and promote the proliferation of beneficial bacteria, and effectively regulate the balance of vaginal flora; adhesion of harmful bacteria can be effectively weakened, biological membranes wrapping bacterial colonies of the harmful bacteria are destroyed, and drug resistance of the harmful bacteria is reduced; the vagina inflammation can be effectively relieved, and vagina mucosa injury can be repaired. The composition is suitable for treating vaginitis diseases.

The utility model relates to a kind of perineum cleaning main body and self-service nursing device for family, belong to flusher technical field.It includes several prisms, water flow groove is formed between the prism, the one end of several prisms is arc head, one or several water outlets are equipped on the prism, the one end of several prisms away from arc head is equipped with water inlet, water inlet is connected with water outlet in the main body, and the prism is evenly distributed in annular;The front end of arc head is equipped with a guide head.The utility model provides a kind of gynecological inner vagina cleaning main body, the front end of which is equipped with guide head, so that insertion process is more smooth and comfortable, and at the same time, combined with the design of multiple prism and scientific distribution of water outlet, it helps women to achieve professional, comprehensive, dead-angle-free inner vagina care at home, effectively preventing or treating gynecological diseases such as inner vagina inflammation.

The invention discloses a Lactobacillus paracasei strain for regulating local secretory immune globulin and systemic immune globulin of a host to enhance infection resistance, and belongs to the technical field of microorganisms. The lactobacillus paracasei provided by the invention has the effects of reducing vaginal mucosa injury and inhibiting vagina inflammation, and the effects are specifically reflected as follows: (1) the expression of a polymeric immune globulin receptor gene of an organism is improved; (2) promoting the secretion of secretory immune globulin sIgA of the body; (3) promoting secretion of immune globulin IgG of the body; (4) the generation of a chemotactic factor CCL20 of an organism is reduced; (5) reducing secretion of granulocyte colony stimulating factors of the body; (6) the secretion of TNF-alpha is inhibited, and the secretion of IL-10 is promoted; (7) improving pathological characterization of the organism; and (8) improving glycogen staining characterization after fungal infection of the organism. Therefore, the lactobacillus paracasei has a huge application prospect in products for improving vaginal mucosa injury and inhibiting vagina inflammation.

The vagina inflammation packing bolt comprises a baffle, the baffle is fixedly connected to the outer side of the front end of a mounting shell, a plurality of sets of annularly-distributed inserting holes are formed in the middle of the baffle, inserting rods penetrate through the inner sides of the inserting holes and are in sliding connection with the inner sides of the inserting holes, the inserting rods are fixedly connected to the outer side of the front wall of a lubricating ring and are annularly distributed, and the lubricating ring is fixedly connected to the front end of the inner side of a protective shell. A piston hole is formed in the middle of the rear wall of the mounting shell, a push rod penetrates through the inner side of the piston hole and is in sliding connection with the inner side of the piston hole, and a pull plate is fixedly connected to the front end of the push rod. According to the vagina inflammation tampon, when the tampon needs to be used, a baffle ring is pulled out of an insertion rod, then the insertion rod is separated from an insertion hole, accordingly, a protection shell can be taken down from the outer side of a mounting shell, a lubricating ring makes contact with the outer wall of the mounting shell in the process of pulling out the protection shell, lubricating liquid is smeared on the surface of the mounting shell, resistance in the tampon insertion process is reduced, and the service life of the tampon is prolonged. Therefore, the comfort of the filling bolt is improved.

The utility model discloses a disposable vagina powder applicator which comprises a hard shell, the top end of the hard shell is connected with an air bag in a clamped mode, the top of the air bag is provided with an air vent, a medicine blocking assembly is inserted into the air vent, the other end of the hard shell is fixedly connected with a feeding hard tube, and the end of the outer wall of the hard shell is further connected with a protective shell in a clamped mode and covers the outer side of the feeding hard tube. A sealing ring is arranged at one end between the inner surface of the protective shell and the outer surface of the feeding hard pipe, a medicine blocking head is clamped to one end in the feeding hard pipe, a sealing patch is bonded to the outer wall of the top of the air bag, the medicine blocking assembly comprises a ventilation pipe, and the ventilation pipe is inserted into the ventilation opening. The feeding hard tube is stuffed into the vagina, then the air bag is pinched, so that air in the air bag is input into the feeding hard tube through the hard shell, medicine powder is input into the vagina through blowing of the air, operation is easy, the feeding device belongs to disposable articles, and vagina inflammation is prevented from being induced.

The invention discloses an application of pulsatilla saponin B5 with a structure shown as a formula I in preparation of a medicine for vaginitis and / or cervicitis. The vaginitis is bacterial vaginitis, and the cervicitis is bacterial inflammation of the cervix and the vagina. The invention relates to a spray for vaginitis and / or cervicitis, in particular to bacterial vaginitis and / or bacterial cervix and vagina inflammation and application thereof. The spray is prepared from the following components in parts by weight: 0.5 to 5 parts of pulsatilla saponin B5, 0.05 to 1 part of sucralose, 0.01 to 0.05 part of benzalkonium chloride and 100 parts of water.