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Use of konjak and its extract in preparation of medicine for treating acute and chronic bronchitis

A technology of chronic bronchitis and konjac extract, applied in the field of use in medicine, can solve the problems of poppy shell poisoning, easy addiction, and children's prohibition, and achieve the effects of definite clinical curative effect, strong stability and high safety.

Inactive Publication Date: 2009-09-09
朱淑华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current western medicine for treating chronic bronchitis adopts symptomatic treatment for the disease, which lacks an overall concept and is not easy to recover
However, the commercially available Chinese patent medicines for the treatment of chronic bronchitis and the combination of Chinese and Western medicines have the following problems: 1. The effects of relieving cough, relieving asthma and eliminating phlegm need to be taken for a long time. If the medicine is stopped, the condition will relapse very quickly; The opium poppy husk of the Chinese Pharmacopoeia 2000 edition has "the poppy husk is poisonous and addictive, and should not be taken regularly, and children are forbidden to take it"; 3. Some Chinese and Western medicines for the treatment of chronic bronchitis contain chlorpheniramine maleate and Drugs such as Clenrole hydrochloride have side effects such as drowsiness, which are easy to cause inconvenience in use; 4. Some Chinese patent medicines for the treatment of chronic bronchus have certain side effects, which can only treat the symptoms, not the root cause
"Currently, there is no relevant report about the treatment of acute and chronic bronchitis with konjac, and there is no fast-acting, significant curative effect, and safe Chinese patent medicine for the treatment of chronic bronchitis.

Method used

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  • Use of konjak and its extract in preparation of medicine for treating acute and chronic bronchitis
  • Use of konjak and its extract in preparation of medicine for treating acute and chronic bronchitis
  • Use of konjak and its extract in preparation of medicine for treating acute and chronic bronchitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 The preparation of pharmaceutical capsule of the present invention

[0034] Raw material: Schisandra chinensis 667g, konjac 2000g, auxiliary materials: micropowder silica gel, starch, dextrin, microcrystalline cellulose, lactose or a mixture thereof, appropriate amount

[0035] Preparation: crush schisandra into coarse powder, add 70% ethanol for reflux extraction twice; crush konjac into coarse powder, add 60% ethanol for percolation at a percolation speed of 1ml / min·kg, and collect percolation liquid. Combining Schisandra reflux extract and konjac percolation liquid, recovering ethanol under reduced pressure, concentrating under reduced pressure to form a clear paste, adding appropriate amount of auxiliary materials, spray drying, dry granulation, and packing into capsules to obtain the product.

Embodiment 2

[0036] Embodiment 2 Preparation of pharmaceutical capsules of the present invention

[0037] Raw material: Schisandra chinensis 667g, konjac 2000g, auxiliary materials: micropowder silica gel, starch, dextrin, microcrystalline cellulose, lactose or a mixture thereof, appropriate amount

[0038] Preparation: crush schisandra into coarse powder, add 25% ethanol for reflux extraction twice; crush konjac into coarse powder, add 60% ethanol for percolation at a percolation speed of 10ml / min·kg, and collect percolation liquid. Combining Schisandra reflux extract and konjac percolation liquid, recovering ethanol under reduced pressure, concentrating under reduced pressure to form a clear paste, adding appropriate amount of auxiliary materials, spray drying, dry granulation, and packing into capsules to obtain the product.

Embodiment 3

[0039] Embodiment 3 Preparation of pharmaceutical capsules of the present invention

[0040] Raw material: Schisandra chinensis 667g, konjac 2000g, auxiliary materials: micropowder silica gel, starch, dextrin, microcrystalline cellulose, lactose or a mixture thereof, appropriate amount

[0041]Preparation: crush schisandra into coarse powder, add 95% ethanol for reflux extraction twice; crush konjac into coarse powder, add 95% ethanol for percolation at a percolation speed of 0.5ml / min·kg, and collect percolation liquid. Combining Schisandra reflux extract and konjac percolation liquid, recovering ethanol under reduced pressure, concentrating under reduced pressure to form a clear paste, adding appropriate amount of auxiliary materials, spray drying, dry granulation, and packing into capsules to obtain the product.

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PUM

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Abstract

The invention provides the use of konjac Amorphophallus rivieri Durieu and its extract in the preparation of medicine for treating acute and chronic bronchitis. The invention also provides a pharmaceutical composition containing konjac and schisandra as raw materials. The invention also provides the preparation method and application of the pharmaceutical composition. The konjac of the invention is used alone or in combination with other medicines, has definite clinical curative effect, high safety, strong stability and controllability, and provides a new choice for clinical treatment of acute and chronic bronchitis.

Description

technical field [0001] The invention relates to a new application of medicine, in particular, the application of konjac in the preparation of medicine for treating chronic bronchitis. Background technique [0002] Chronic bronchitis mainly occurs in winter and spring, and belongs to frequently-occurring disease and commonly encountered diseases. People over 40 years old are prone to suffer from the disease. 1998. According to national statistics, chronic bronchitis is 9.7% in rural areas, 12.4% in urban areas, with an average of 11.05%, and about 18% in middle-aged and elderly people over the age of 40. In 2003, it accounted for 8.2% in cities and 7.75% in rural areas. People about 15%. The western medicine for the treatment of chronic bronchitis adopts symptomatic treatment to this disease at present, lacks overall concept, is difficult for recovery from illness. However, the commercially available Chinese patent medicines for the treatment of chronic bronchitis and the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/888A61K36/57A61P11/00
CPCA61K36/888A61P11/00A61P11/06A61P11/08A61P29/00A61K36/882
Inventor 朱淑华
Owner 朱淑华