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Method for preparing gamma-aminobutyric acid by using rice grain as raw material

A technology of aminobutyric acid and rice, which is applied in the field of preparation of γ-aminobutyric acid, can solve the problems of low production cost, low production rate and high production cost, and achieves the advantages of less environmental pollution, high product activity and low production cost. Effect

Inactive Publication Date: 2010-01-27
CENTRAL SOUTH UNIVERSITY OF FORESTRY AND TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are two main methods for preparing γ-aminobutyric acid: one is the natural extraction method, which is to extract natural γ-aminobutyric acid from animal and plant raw materials (such as tea leaves) (leaching with organic solvents, filtering out organic solvent, and then through spray drying or freeze-drying), the γ-aminobutyric acid produced by this method is safe to eat and has a wide range of uses, but the production rate is very low and the production cost is high, such as extracting γ-aminobutyric acid from tea leaves -Products with 20% aminobutyric acid content, the production cost is more than 1 million yuan / ton; the second method is chemical organic synthesis method, the production rate of γ-aminobutyric acid produced by this method is very high, and the production cost Very low, for example, the production cost of a product with 20% gamma-aminobutyric acid content is about 50,000 yuan / ton, but it cannot be used in the fields of food and medicine because of possible harmful residues during organic synthesis , can only be used as chemical raw materials

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] (1) Weigh 4 kg of rice, crush it into a fineness of 90 mesh, add 24 kg of drinking tap water, soak for 7 hours, heat to 75 ° C for 15 minutes to gelatinize; (2) add 20 grams of starch to the gelatinized rice paste Enzyme, incubate at 40°C for 65 minutes to prepare amylase-treated rice milk; add 12 grams of protease to the amylase-treated rice milk and incubate at 35°C for 45 minutes to prepare protease-treated rice milk; heat protease Keep the treated rice milk at 90°C for 5 minutes to prepare rice milk; (3) after the temperature of the rice milk drops to room temperature, inoculate the expanded cultured γ-aminobutyric acid-producing Lactobacillus plantarum, and incubate at 35°C Ferment and cultivate for 3 days, heat to 85°C and sterilize for 18 minutes; (4) Filter the fermented rice milk emulsion with a plate basket to remove the coarse residue; (5) Concentrate the filtrate through a membrane fractional filtration, and then dry the concentrate under vacuum at room tempe...

Embodiment 2

[0014] (1) Weigh 5 kg of rice, break it into 80 mesh fineness, add 33 kg of drinking water, soak for 5 hours, heat to 80 ° C for 17 minutes to gelatinize; (2) add 35 g of starch to the gelatinized rice paste Enzyme, incubate at 45°C for 70 minutes to prepare amylase-treated rice milk; add 10 grams of protease to the amylase-treated rice milk, and incubate at 37°C for 50 minutes to prepare protease-treated rice milk; heat The protease-treated rice milk was kept at 85°C for 7 minutes to prepare rice milk; (3) after the temperature of the rice milk dropped to room temperature, inoculate the expanded and cultured Lactobacillus plantarum producing γ-aminobutyric acid, and inoculate at 32°C Ferment and cultivate for 4 days, heat to 90°C and sterilize for 10 minutes; (4) Filter the fermented rice milk emulsion with a plate basket to remove the coarse residue; (5) Concentrate the filtrate through a membrane fractionation filtration, and then vacuum-dry the concentrate at room temperatu...

Embodiment 3

[0017] (1) Weigh 8 kg of rice, break it into 90 mesh fineness, add 48 kg of drinking tap water, soak for 8 hours, heat to 80 ° C for 20 minutes; (2) add 120 grams of starch to the gelatinized rice paste Enzymes were incubated at 45°C for 90 minutes to prepare amylase-treated rice milk. Add 40 grams of protease to the amylase-treated rice milk, and incubate at 40°C for 65 minutes to obtain protease-treated rice milk; heat the protease-treated rice milk to 85°C for 8 minutes to obtain rice milk; 3) After the temperature of the rice milk drops to room temperature, inoculate the expanded and cultured Lactobacillus brevis producing γ-aminobutyric acid, ferment and cultivate it at 37°C for 4 days, and heat it to 90°C for 10 minutes to sterilize; (4) The fermented rice milk emulsion is filtered with a plate basket to remove the coarse slag, and then centrifuged to remove the slag; (5) The centrifuged liquid is concentrated through 5 times of membrane classification filtration, and th...

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Abstract

The invention discloses a preparation method for gamma-aminobutyric acid from rice, comprising the following steps : (1) grinding, marinating, gelatinizing of rice; (2) a proper amount of amylase is added into the gelatinized rice, and then the mixture is heated at a constant temperature 40 to 50 degrees C for 60 to 90 minutes and the rice slurry processed by amylase is obtained; (3) the rice slurry processed by amylase is added with protease, and then the mixture is heated at a constant temperature 30 to 40 degrees C for 40 to 70 minutes and the rice slurry processed by protease is obtained; (4) the rice slurry processed by protease is heated to 80 to 90 degrees C holding for 5 to 8 minutes and the rice emulsion is obtained; (5) when the rice emulsion is cooled to the ambient temperature, the bacillus is inoculated, and then the rice emulsion is fermented and cultured for 3 to 5 days, at 30 to 40 degrees C, and then the rice emulsion is sterilized for 15 to 20 minutes at 80 to 90 DEG C; (6) filtering and deslaging; (7) the gamma-aminobutyric acid is prepared by concentration and drying. The preparation method for gamma-aminobutyric acid from rice has the advantages that: the gamma-aminobutyric acid content of the product is more than 40 percent, and the gamma-aminobutyric acid has high activity and food safety and can be widely used in health care, foods, medical and chemical engineering fields.

Description

technical field [0001] The present invention relates to a method for preparing gamma-aminobutyric acid, in particular to a method for preparing gamma-aminobutyric acid which is natural and highly active from rice and can be widely used in the fields of medicine, health food and chemical industry . Background technique [0002] γ-aminobutyric acid (GABA) widely exists in nature and is a natural amino acid composed of non-protein. It can be synthesized from glutamic acid (Glu) through glutamate decarboxylase EC4.1.1.15, abbreviated as GAD or GDC), is obtained by catalytic transformation. It is an important inhibitory neurotransmitter in the mammalian central nervous system and has important physiological functions. The physiological activities that have been reported include regulating blood pressure and promoting mental stability. , promote blood flow in the brain, enhance brain vitality, nourish nerve cells, increase growth hormone secretion, strengthen the liver and kidney...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12P13/00C12R1/24C12R1/25
Inventor 林亲录
Owner CENTRAL SOUTH UNIVERSITY OF FORESTRY AND TECHNOLOGY