Preparation method and application for general saponin of cortex ilecis rotundae

A technology of total saponins and salvage, which is applied in the fields of medicines and health foods for treating cardiovascular and cerebrovascular diseases and their preparation, and can solve problems such as unclear effective parts and the like

Inactive Publication Date: 2008-01-09
李超生 +1
View PDF0 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since the alcohol extract of Jiubingying is a crude preparation, its exact effective part is not clear in the prior art

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method and application for general saponin of cortex ilecis rotundae
  • Preparation method and application for general saponin of cortex ilecis rotundae
  • Preparation method and application for general saponin of cortex ilecis rotundae

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0100] Example 1: Rescue 2000g of Bing coarse powder, reflux extraction with 6 times 80% ethanol three times, extract for 2, 1, 1 hour respectively, filter, combine the filtrates, concentrate to extract, add 6000ml of water, heat in a water bath, stir , left to stand overnight, filtered, the filtrate was concentrated to 1000ml, allowed to cool to room temperature, filtered, the precipitate was washed three times with an appropriate amount of water, dried to obtain 40g of total saponins, and the content of total saponins was determined to be 85% according to law.

Embodiment 2

[0102] Take the total saponins of Jiubing prepared by the method of Example 1, adopt the preparation method of infusion solution known in the art, and prepare the total saponins of Jiubing sodium chloride injection and the total saponins of Jiubing glucose injection: Jiubing total saponins Total saponins 60mg, sodium chloride 2.25g, made into Jiubing total saponins sodium chloride injection, its specification is 500ml, intravenous injection, 1 bottle each time, once a day; Jiubing total saponins 60mg, glucose 12.5g , make Jiubing Total Saponin Glucose Injection, its specification is 500ml, intravenous injection, 1 bottle each time, once a day.

Embodiment 3

[0103] Embodiment 3: Take 30 g of total saponins of jiubing prepared by the method of example 1, add appropriate amount of water for injection, adjust the pH value to 7 with sodium carbonate, stir and dissolve, and add 10-15 g of total saponins of jiubing equivalent to The % amount of mannitol for injection is sterilized and filtered, the content is determined, and 1000 pieces are divided into 30 mg / piece, sealed, and the product is obtained. Intravenous injection, each 60mg, once a day.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention relates to an iron holly bark total saponin for curing cardio-cerebral vascular system diseases of coronary heart disease, angina pectoris, apoplexy and cerebral infarction, medicine composite containing iron holly bark total saponin and its extraction separation method. Said method includes the following steps: using ethyl alcohol to extract iron holly bark to obtain extract, adding water, centrifugal separation, concentrating supernatant fluid, centrifugal separation, washing precipitate, drying so as to obtain the iron holly bark total saponin whose content can be up to above 50%; mixing said iron holly bark total saponin with oral preparation auxiliary material or injection preparation auxiliary material so as to obtain various oral preparations and injection preparation containing iron holly bark total saponin.

Description

technical field [0001] The invention relates to a medicine for treating diseases of the cardiovascular and cerebrovascular systems, a health food and a preparation method thereof, in particular to the total saponins of the effective part of the traditional Chinese medicine jiubing, the medicine containing the total saponins of jiubing and the preparation method thereof. Compositions and their corresponding methods of preparation. Background technique [0002] Jiubing is the bark of Ilex rotunda Thunb., a plant in the Ilex family Ilex family. It is mainly produced in Guangxi and Guangdong provinces. It has the effects of clearing away heat and detoxification, reducing swelling and relieving pain. For colds, tonsillitis, sore throat, acute gastroenteritis, rheumatic bone pain; external use for bruises, carbuncle furuncle sores, traumatic bleeding, burns and scalds. The chemical components mainly contain triterpenoid saponins, flavonoid glycosides, phenols, tannins, etc., and ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P9/10A61P9/06A61K129/00
Inventor 李超生
Owner 李超生
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap