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Pharmaceutical composition used for ulcer of upper digestive tract

A technology for digestive tract ulcers and compositions, applied in the field of medicine, to achieve the effects of small quality differences, simple preparation process, and uniform and stable drug quality

Inactive Publication Date: 2008-02-27
JIANGYIN TIANJIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no report on the use of dandelion, bletilla and their interaction and compatibility prescriptions for the preparation of pharmaceutical compositions for treating upper gastrointestinal ulcers.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Embodiment 1: the preparation of pharmaceutical composition granule of the present invention

[0070] Dandelion 200g white and 200g

[0071] Weigh the dandelion and dandelion in said parts by weight and crush them into coarse powder, soak in water for 1.0 hour, decoct twice, add 13 times of water for the first time, extract for 2.0 hours, add 10 times of water for the second time, extract for 1.0 hour , combine the water extracts, filter, concentrate the filtrate to a relative density of 1.10-1.15, cool to room temperature, add ethanol until the alcohol content is 70%, stir evenly, refrigerate, let stand for 24 hours, filter, and recover ethanol from the filtrate under reduced pressure Continue to concentrate to obtain a thick paste until there is no alcohol smell, add appropriate amount of powdered sugar and dextrin, mix with water, granulate, and dry to obtain.

Embodiment 2

[0072] Embodiment 2: the preparation of pharmaceutical composition cavity capsule of the present invention

[0073] Dandelion 150g white and 150g

[0074] Or Dandelion 200g white and 150g

[0075] Weigh the dandelion and dandelion in said parts by weight and crush them into coarse powder, soak in water for 1.0 hour, decoct twice, add 13 times of water for the first time, extract for 2.0 hours, add 10 times of water for the second time, extract for 1.0 hour , combine the water extracts, filter, concentrate the filtrate to a relative density of 1.10-1.15, cool to room temperature, add ethanol until the alcohol content is 70%, stir evenly, refrigerate, let stand for 24 hours, filter, and recover ethanol from the filtrate under reduced pressure Continue to concentrate until there is no alcohol smell to obtain a thick paste, mix with appropriate amount of powdered sugar and water, granulate, dry, and put into empty capsules.

Embodiment 3

[0076] Embodiment 3 pharmaceutical composition tablet preparation of the present invention

[0077] Dandelion 250g white and 250g

[0078] Or Dandelion 200g white and 250g

[0079] Weigh the dandelion and dandelion in said parts by weight and crush them into coarse powder, soak in water for 1.0 hour, decoct twice, add 13 times of water for the first time, extract for 2.0 hours, add 10 times of water for the second time, extract for 1.0 hour , combine the water extracts, filter, concentrate the filtrate to a relative density of 1.10-1.15, cool to room temperature, add ethanol until the alcohol content is 70%, stir evenly, refrigerate, let stand for 24 hours, filter, and recover ethanol from the filtrate under reduced pressure Continue to concentrate until there is no alcohol smell to obtain a thick paste, mix with powdered sugar and dextrin, granulate, compress into tablets, and dry to obtain.

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PUM

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Abstract

The invention provides a pharmaceutical composition for treating upper digestive tract ulcer and its preparing process, wherein the raw materials of the medicinal constituents mainly include dandelion and bletilla tuber by a predetermined weight ratio. The composition can be made into any clinically and pharmaceutically acceptable dose forms, preferably oral preparations. The medicinal composition has the effects of protecting gastric mucosa, heat clearing, detoxicating and haemostasis.

Description

1. Technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a pharmaceutical composition for upper digestive tract ulcer and a preparation method thereof. The raw materials of the medicinal components contained in the pharmaceutical composition are dandelion and radishes. 2. Background technology [0002] Upper gastrointestinal ulcers refer to ulcers in the digestive tract above the flexor ligament of the duodenum, mostly gastric ulcers. The main manifestations are chronic, recurrent, rhythmic abdominal pain, belching, acid reflux, salivation, nausea, vomiting, insomnia, hyperhidrosis, and bradycardia. Upper gastrointestinal bleeding, perforation, pyloric obstruction and cancer are the four major complications of peptic ulcer. [0003] Upper gastrointestinal ulcers belong to the category of epigastric pain and acid regurgitation in TCM theory. Most of them are caused by internal and external pathogenic factors, or intern...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P1/04
Inventor 黄振华
Owner JIANGYIN TIANJIANG PHARMA
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