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Medicinal composition for treating leukocytopenia and preparation thereof

A technology for leukopenia and composition, which is applied in the field of pharmaceutical compositions and their preparation, pharmaceutical compositions for the treatment of leukopenia and their preparation, can solve the problems of difficulty in achieving ideal therapeutic effects, different action mechanisms, and the like, and achieves promotion of hematopoiesis. Stem cell proliferation, inhibition of hematopoietic damage, and safe administration

Inactive Publication Date: 2008-09-10
BEIJING ZHONGTAI TIANHE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many kinds of drugs that can promote leukocyte production in clinical application, such as vitamin B6, leucogen, batyl alcohol, inosine, deoxyribonucleotides, adrenocortical hormone, etc., because of their different mechanisms of action, it is still difficult to achieve the desired effect. treatment effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Recipe composition:

[0035] Ganoderma lucidum 100g Salvia 60g Rehmannia glutinosa 60g Polygonum multiflorum 40g

[0036] Chuanxiong 40g Golden buckwheat 60g Burnet 30g Codonopsis 30g

[0037] Astragalus 40g Lycium barbarum 40g Eucommia 40g Angelica 30g

[0038] Ligustrum lucidum 30g Epimedium 40g Hawthorn 30g Licorice 12g

[0039] Preparation:

[0040] (1) Get Ganoderma lucidum, break it up, and set aside;

[0041] (2) Get Danshen, Rhizoma Chuanxiong, and Golden Buckwheat, grind them into coarse powder, and set aside;

[0042] (3) Get the above-mentioned medicinal materials, extract with 10 times the amount of 75% ethanol under reflux for 2 hours, extract the alcohol solution and filter; Double the amount of 75% ethanol for reflux extraction for 2 hours, extract the alcohol solution and filter; combine the filtrates, recover the ethanol under reduced pressure and concentrate to a clear ointment with a relative density of 1.30 (55°C), and use the dregs for later us...

Embodiment 2

[0047] Recipe composition:

[0048] Ganoderma lucidum 50g Salvia 30g Rehmannia glutinosa 30g Polygonum multiflorum 20g

[0049] Chuanxiong 20g Golden buckwheat 30g Burnet elm 15g Codonopsis 15g

[0050] Astragalus 20g Lycium barbarum 20g Eucommia 20g Angelica 15g

[0051] Ligustrum lucidum 15g Epimedium 20g Hawthorn 15g Licorice 6g

[0052] Sucrose 400g Sodium Benzoate 3g

[0053] Preparation:

[0054] (1) Get Ganoderma lucidum, break it up, and set aside;

[0055] (2) Get Danshen, Rhizoma Chuanxiong, and Golden Buckwheat, grind them into coarse powder, and set aside;

[0056] (3) Get above-mentioned medical material, reflux extraction with 10 times amount of 75% ethanol for 2 hours, extract the alcohol solution and filter; Add 10 times the amount of 75% ethanol to extract for 1.5 hours, extract the alcohol solution for filtration; Double the amount of 75% ethanol for reflux extraction for 1 hour, extract the alcohol solution and filter; combine the filtrates, recover th...

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Abstract

The invention relates to a medicine combination used for treating aleukocytosis and a preparation method of the medicine combination. The medicine combination is made of medicine materials with weight proportion as follows: 20 to 100 parts of mythic fungus, 10 to 30 parts of salvia, 10 to 30 parts of prepared radix rehmanniae, 10 to 30 parts of Chuanxiong, 10 to 30 parts of cymosum, 10 to 20 parts of burnet, 10 to 20 parts of lanceolata, 10 to 20 parts of astragalus, 10 to 20 parts of wolfberry fruit, 10 to 20 parts of eucommia ulmodies, 10 to 20 parts of angelica sinensis, 10 to 20 parts of ligustrum lucidum, 10 to 20 parts of epimedium, 10 to 20 parts of hawthorn and 5 to 10 parts of glycyrrhiza. The medicine combination has the functions of supplementing Qi, nourishing blood, nourishing liver and kidney, detoxifying and dispersing masses and can evidently increase white blood cell. In addition, the medicine combination has definite effect on treating the aleukocytosis and low immune function caused by cancer radio therapy without any adverse effect and is safe to be taken.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for treating leukopenia and a preparation method thereof, belonging to the technical field of new drugs. Background technique [0002] Leukopenia is a common clinical blood disease. When the white blood cell count in peripheral blood is lower than the specified value due to bone marrow injury, abnormal distribution of peripheral circulating granulocytes, increased demand for granulocytes in extravascular tissues, accelerated consumption, or mixed factors, it is collectively referred to as leukopenia. The main clinical manifestations are fatigue, palpitations, shortness of breath, insomnia and forgetfulness, lack of appetite, dizziness, tinnitus, five upset fever, spontaneous sweating, night sweats, soreness of the waist and knees, chills, abdominal distension, loose stool or constipation, nocturnal emission, impotence ,...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P7/00
Inventor 何俊保
Owner BEIJING ZHONGTAI TIANHE SCI & TECH
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