Red rice yellow wine with antihypertensive function

Abstract

The invention relates to a red yeast yellow wine having the blood pressure lowering function; and the red yeast yellow wine is prepared by the following processes of: taking glutinous rice as a raw material, steaming and boiling the glutinous rice, and then adding distillers yeast made of red yeast and supplementary materials as well as functional red yeast wine lees with the weight percent of 10 percent to 20 percent of the raw material for undergoing initial fermentation and secondary fermentation, then pressing the mixture to make the red yeast yellow wine having the blood pressure lowering function, and recovering the red yeast wine lees. The invention fully utilizes the supplementary material of red yeast wine lees for producing the red yeast wine, thereby increasing the added value and preparing the red yeast yellow wine with high GABA content and blood pressure lowering function; and the red yeast yellow wine has an unexpected effect to the treatment and prevention of hypertension, and also has the auxiliary blood pressure lowering function.

Description

technical field [0001] The invention relates to a metabolite of red yeast rice, in particular to a red yeast rice wine with the function of lowering blood pressure. Background technique [0002] Hypertension is a common disease with elevated blood pressure in the systemic circulation as the main clinical manifestation. It often involves blood vessels, especially small and small arteries throughout the body, and important organs such as the heart, kidney, and brain, and often causes stroke and chronic cardiac insufficiency. , renal failure and other complications, the existing antihypertensive drugs can be divided into: (1) diuretics, hydrochlorothiazide, etc., but the use of these drugs will cause adverse reactions such as aggravating hyperlipidemia and reducing glucose tolerance; (2) ) Angiotensin I-converting enzyme inhibitors and angiotensin II receptor blockers, captopril, losartan, etc., but the use of these drugs may cause adverse reactions such as hypotension, cough, ...

AI Technical Summary

Problems solved by technology

In 1979, Professor Yuan Tengzhang of Japan Agricultural University, based on Mr. Zhu Danxi's TCM theory records, revealed that red yeast rice has the effect of promoting blood circulation, and found that the products fermented with red yeast rice have the effects of lowering blood fat, blood pressure, and blood sugar on the human body; 1987 Kohama et al. isolated GABA and acetylcholine from red yeast rice in 2010 and have the effect of lowering blood pressure. Chinese patent application (02158370.6) Monascus mutant strain and its use in the preparation of active fermentation products for lowering blood pressure. Although it has screened GABA content is higher, Monascus mutant strain with low citrinin content and related to its cultivation method, pharmaceutical composition and food additive, but the screening of the strain is difficult, and the survival rate after mutation is low, and the random factor is high; in addition, from the patent application document It is impossible to know whether the GABA in Monascus or its fermentation product is inactivated by temperature, pH value and other factors, thus losing the medicinal property of treating hypertension

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