Use of water hyacinth extract in preparing lipid-lowering medicine
A technology of extract and water hyacinth, applied in the field of preparation of water hyacinth extract
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example 1
[0012] Example 1 Preparation of Water Hyacinth Extract
[0013] Wash the stems, leaves and / or roots of the harvested water hyacinth, dry the surface water, squeeze the fresh juice with a press, and dry it at 50°C. Add 30-95 % ethanol or methanol or acetone, soak at room temperature for 2-3 days, collect the ethanol extract, recover the ethanol, combine the extract with fresh juice, concentrate under reduced pressure to a specific gravity of 1.1-1.2, and then extract with the same volume of chloroform several times until the chloroform Until the color of the extract becomes colorless and transparent, the chloroform extracts are combined, and the chloroform is recovered to obtain the chloroform extract of water hyacinth. The remaining aqueous phase was sequentially extracted with ethyl acetate or n-butanol in the above-mentioned manner to obtain the corresponding extract. Finally, the remaining aqueous phase was filtered, concentrated and evaporated to dryness to obtain a water...
example 2
[0014] Example 2 The hypolipidemic effect of the total extract of water hyacinth
[0015] After 60 18-22g male Kunming mice were fed adaptively for 3 days, they were randomly divided into 6 groups according to body weight, normal control group, fatty liver model group (i.e. model control group), compound methionine choline tablet positive control, water The doses of the cucurbit ethyl acetate extract group are calculated based on the amount of crude drug, which are 3g / kg group, 6g / kg group and 9g / kg group respectively. Except that the normal group was fed with common feed, all the other groups were fed with high-fat feed every day, 30% ethanol (0.15ml / 10g) was administered orally, and from the first day of the experiment, 40% CCl 4 Sunflower oil solution (0.05ml / 10g) was injected subcutaneously, and then injected every 3 days for a total of 4 times. The normal group was injected with the same dose of normal saline at the same time. Every afternoon, except the normal group an...
example 3
[0020] Example 3 Anti-fatty liver effect of water hyacinth total extract
[0021] After 60 18-22g male Kunming mice were fed adaptively for 3 days, they were randomly divided into 6 groups according to body weight, normal control group, fatty liver model group (i.e. model control group), compound methionine choline tablet positive control, water For the cucurbit ethyl acetate extract group, the dosage is calculated based on the amount of crude drug, which is 3g / kg group, 6g / kg group and 9g / kg group respectively. Except that the normal group was fed with common feed, all the other groups were fed with high-fat feed every day, 30% ethanol (0.15ml / 10g) was administered orally, and from the first day of the experiment, 40% CCl 4 Sunflower oil solution (0.05ml / 10g) was injected subcutaneously, and then injected every 3 days for a total of 4 times. The normal group was injected with the same dose of normal saline at the same time. Every afternoon, except the normal group and the m...
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