Alveolar bone repairing material, preparation method and uses thereof

Abstract

The invention provides an alveolar bone restorative material which comprises compound bone powder and a scaffold material, wherein the compound bone powder is formed by soaking bone powder in solution of an osteoinduction material, and the ratio of the bone powder to the solution of the osteoinduction material is between 1to1 and 1to100 (mass / volume ratio); the scaffold material consists of a macromolecular substance containing carboxyl and a macromolecular substance containing amino group which crosslink and form gel upon the function of an activator, and the weight ratio of the compound bone powder and the scaffold material is between 10< -3 > to1 and 1to1. The invention also provides a preparation method and application of the alveolar bone restorative material. The material has the biological hemostasis function and bone guiding function, has certain osteoinduction activity for bone growth, and can promote the growing and reconstruction of bone tissue at the surrounding defect area of a dental implant so as to obtain an ideal interface where the implant combines with the bone; and when used for alveolar bone restoration, dental implantation and the like, the material plays a role in inducing bone restoration, hemostasis and anti-adhesion.

Description

technical field

[0001] The invention relates to an alveolar bone repair material, in particular to a bone powder composite osteoinductive material combined with a degradable bracket to form an alveolar bone repair material, a preparation method and an application thereof, belonging to the field of medical materials. Background technique

[0002] In recent years, dental implants have been widely used clinically to restore missing teeth, but insufficient alveolar bone in the implanted area has become a common problem faced by dental implant surgery. In the treatment of periodontal disease, how to repair and regenerate the damaged alveolar bone is a major problem at present. In order to solve these problems, people have studied a variety of bone repair methods, among which bone materials are widely used in oral surgery and have achieved good repair results.

[0003] At present, there are many kinds of bone graft materials that can be used to repair bone defects in dental impla...