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Carotenoid preparation and use thereof and feedstuff containing the preparation and preparation method thereof

A carotene and preparation technology, applied in the application, food preparation, animal feed and other directions, can solve problems such as difficulty, uneven distribution of active ingredients, large particle size, etc., to reduce surface oxidation loss, be beneficial to absorption and utilization, and coloring effects. Good results

Active Publication Date: 2009-04-01
ZHEJIANG MEDICINE CO LTD XINCHANG PHAMACEUTICAL FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this process also brings the following problems: as we all know, in order to strengthen the nutrition of fish and the absorption of carotenoids, a large amount of oil is often added to fish feed. This oil is a mixture of fish oil and vegetable oil. It is added by post-spraying technology, that is, after the fish feed is extruded and puffed, a large amount of oil is sprayed on its surface. The oil is lipophilic, and the astaxanthin to be added later is dissolved in water and added. It becomes very difficult to evenly spray the astaxanthin dissolved in water on the feed particles covered with a layer of oil. The presence of hydrophobic oil on the surface of the particles makes the nano-scale astaxanthin dissolved in water enter the pores of the feed particles The resistance of the feed particles is greatly enhanced, so these astaxanthins can only be distributed on the surface of the particles and cannot enter the interior; moreover, if the astaxanthin is not completely dissolved in water, the presence of small particles will block the internal channels of the feed particles and prevent the shrimp from feeding. The cyanine penetrates into the interior of the particle and only adsorbs on the surface
However, an obvious defect of this method is that the carotenoids are dispersed in the oil in the state of micropowder, and the particle size is relatively large, up to 20 μm.
As mentioned earlier, such a large particle is enough to block the passage inside the pellet feed, thereby preventing the oil suspension from further penetrating into the pellet, causing many carotenoid crystals to be directly adsorbed on the surface of the pellet feed, which not only easily leads to the loss of active ingredients. The uneven distribution greatly reduces the oil load of the product, and the product quality is not repeatable, and these carotenoids on the surface of the feed particles are also prone to oxidative degradation. More importantly, from the beginning to the end, because the carotenoids are The crystalline state of fine powder exists, which will inevitably lead to a relatively low bioavailability in animals, because the absorption and utilization rate of carotenoids in the crystalline state by organisms is very low, so in order to achieve the ideal coloring effect, more must be added A large amount of carotenoid crystals, which will also cause great waste

Method used

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  • Carotenoid preparation and use thereof and feedstuff containing the preparation and preparation method thereof
  • Carotenoid preparation and use thereof and feedstuff containing the preparation and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0039] Preparation of Astaxanthin 20% Oil Suspension

[0040] Weigh 2.2kg of pure astaxanthin (content: 97.2%), 0.3kg of natural vitamin E and 5.0kg of sunflower oil, mix evenly, put it in a ball mill and grind it for 1.5hr, take it out to get a viscous fluid, and then add 2.5kg Sunflower oil, stirred and mixed evenly to obtain a suspension of astaxanthin oil with better fluidity.

[0041] The content of astaxanthin in the oil suspension is 21.2% as measured by ultraviolet spectrophotometry, and the average particle diameter of the particles in the oil suspension is 4.68 μm as measured by a laser particle size distribution analyzer.

[0042] Dissolution of astaxanthin before spraying

[0043] Take 8.0kg of the above-mentioned astaxanthin oil suspension and mix it with a part of 4800kg of oils to be added (a mixture of fish oil and soybean salad oil, their ratio is 2:1), heat up to 60°C and keep it warm for 1.5hr while stirring. Suspended astaxanthin particles are fully disso...

Embodiment 3-6

[0055] The preparation process of oil suspension in embodiment 3-6 is listed in table 1:

[0056] Preparation of oil suspension in table 1. embodiment 3-6

[0057] Example 3 Example 4 Example 5 Example 6 Types of Carotenoids Lutein Canthaxanthin β-carotene Zeaxanthin Types of Vegetable Oil Sunflower seed oil canola oil Corn oil peanut oil Types of antioxidants BHT BHA synthetic vitamin E synthetic vitamin E Carotenoid content in oil suspension 10wt% 20wt% 30wt% 20wt% Antioxidant content in oil suspension 1% 2.5% 10% 5% Particle size distribution of carotenoids in oil suspension 4μm 6μm 3μm 10μm Raise the melting temperature before spraying 30℃ 40℃ 70℃ 70℃ Warming and dissolving time before spraying 5hr 2hr 0.5hr 1.5hr Carotenoid content in final granules 100mg / kg

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Abstract

The invention provides a carotenoid preparation which relates to oil suspension, a feed which contains the carotenoid preparation, a method used for preparing the feed, and the use as additives of animal feed, food, cosmetics and / or medicines used for the carotenoid preparation. Effective compositions in the feed grains are uniformly distributed; furthermore, most of the effective compositions are distributed in the grains, thus reducing the surface oxidation loss; the carotenoid exists in a dissolved state, thus being beneficial for the absorption and utilization of animals; the animal testsalso show that the coloring effect of the fish is extremely good after the feed grains are used for feeding the fish.

Description

technical field [0001] The present invention relates to a new formulation of carotenoids, in particular to carotenoid preparations in oil suspension, feed containing said carotenoid preparations, methods for preparing said feed, and carotenoid preparations for use in animals The use of additives for feed, food, cosmetics, and / or pharmaceuticals. Background technique [0002] According to the presence or absence of oxygen atoms in the molecular structure formula, carotenoids can be divided into two categories, namely carotene and lutein. The former has no oxygen atom in the molecular structure formula, such as β-carotene, lycopene The structural formula of the latter contains hydroxyl or carbonyl, or contains these two oxygen-containing functional groups, such as canthaxanthin, lutein, astaxanthin, zeaxanthin, etc. Among the carotenoids of the lutein group, if only hydroxyl groups are contained in the molecular structure formula, they tend to show yellow color, and if there ...

Claims

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Application Information

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IPC IPC(8): A23K1/16A23L1/275A61K8/31A61K31/015
CPCA23K1/004A61K47/14A61K47/44A23K1/1606A23D9/007A23L1/2753A61K9/10A23K20/179A23K40/30A23L5/44
Inventor 邵斌许新德周迪王燕峰洪毅敏
Owner ZHEJIANG MEDICINE CO LTD XINCHANG PHAMACEUTICAL FACTORY
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