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Technique for preparing oral liquid for alleviating fever and detoxifcation

A heat-clearing and detoxifying and preparation process technology is applied in the field of preparation of a heat-clearing and detoxifying oral liquid, which can solve the problems of large material flow resistance, many dead ends, and difficult cleaning, and achieves the advantages of ensuring quality and stability, reducing production costs, and reducing operating pressure. Effect

Active Publication Date: 2009-04-15
苏州华辰净化股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This process is cumbersome to operate, and still cannot reduce the amount of ethanol used in pre-extraction, and cannot overcome the adsorption of active carbon to active ingredients. The hollow fiber membrane filtration equipment has the following disadvantages that cannot be overcome: (1) The hollow fiber membrane material is polypropylene (PP), which is harmful to the material The macromolecular substance has a large adsorption capacity, and its performance decays slowly
(2) The hollow fiber membrane polypropylene (PP) material is easy to break, and the working pressure is only 0.1mPa. It is not easy to find after the break, which affects the separation effect
(3) The microporous flow channel of the hollow fiber membrane is a finger-like pore structure, and the inner and outer skin layers are easy to deposit pollutants and difficult to clean.
(4) The hollow fiber membrane channel is small, less than 1 mm, the material flow resistance is large, and the flux per unit square is small
(5) Hollow fiber membrane external pressure dead-end filtration form, no fixed flow channel, no discharge (or small discharge) of retentate, fast fouling, many dead ends, incomplete cleaning, affecting the quality of subsequent products

Method used

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  • Technique for preparing oral liquid for alleviating fever and detoxifcation

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Experimental program
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Effect test

Embodiment 1

[0020] The preparation process of the Qingrejiedu oral liquid according to the present embodiment comprises the following steps:

[0021] (1) Extract the original medicinal liquid: add the raw materials except honeysuckle and scutellaria baicalensis to soak in warm water for 1 hour, decoct twice (after boiling, add honeysuckle and baicalin baicalin), the first time is 1 hour, the second time After 40 minutes, the combined extracts are the original drug solution.

[0022] (2), preparation of heat-clearing and detoxifying extract: filter the original drug solution with a ceramic membrane with a membrane pore size of 200nm, control the filtration pressure at 0.4MPa, and control the temperature at 30°C to 40°C, collect the clear liquid, and concentrate the clear liquid to a relatively high temperature. The density is about 1.17 (80°C), which is the heat-clearing and detoxifying extract.

[0023] (3), preparation of Qingrejiedu oral liquid: take Qingrejiedu extract, add appropriat...

Embodiment 2

[0025] The preparation process of the Qingrejiedu oral liquid according to the present embodiment is as follows:

[0026] (1) Extract the original medicinal liquid: add the raw materials except honeysuckle and scutellaria baicalensis to warm water for 1 hour, decoct twice (after boiling, add honeysuckle and scutellaria baicalensis), the first time is 1 hour, the second time 40 Minutes, the combined extracts are the original drug solution.

[0027] (2), preparation of heat-clearing and detoxifying extract: filter the original drug solution with a ceramic membrane with a membrane pore size of 100nm, control the filtration pressure at 0.3MPa, and control the temperature at 40°C to 45°C, collect the clear liquid, and concentrate the clear liquid to a relatively high temperature. The density is about 1.17 (80°C), which is Qingrejiedu extract (about 2000ml).

[0028] (3), preparation of Qingrejiedu oral liquid: take Qingrejiedu extract, add appropriate amount of corrective agent, a...

Embodiment 3

[0030] The preparation process of the Qingrejiedu oral liquid according to the present embodiment is as follows:

[0031] (1) Extract the original medicinal liquid: add the raw materials except honeysuckle and scutellaria baicalensis to warm water for 1 hour, decoct twice (after boiling, add honeysuckle and scutellaria baicalensis), the first time is 1 hour, the second time 40 Minutes, the combined extracts are the original drug solution.

[0032] (2) Preparation of heat-clearing and detoxifying extract: filter the original drug solution with a ceramic membrane with a membrane pore size of 20nm, control the filtration pressure at 0.2MPa, and control the temperature at 15-20°C, collect the clear liquid, and concentrate the clear liquid to a relative density About 1.17 (80°C), that is, heat-clearing and detoxifying extract (about 2000ml).

[0033] (3) Prepare Qingrejiedu oral liquid: take Qingrejiedu extract, add stevioside and sodium benzoate that have been dissolved in hot pu...

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Abstract

The invention relates to a technology for preparing heat clearing and detoxifying oral liquid, which comprises the following steps: (1) extracting original liquid medicine; (2) further concentrating clear liquid produced through purifying the original liquid medicine to produce heat clearing and detoxifying extract; and (3) preparing the heat clearing and detoxifying extract into liquid medicine with flavouring and water, and filtering and concentrating the liquid medicine to produce the heat clearing and detoxifying oral liquid. Particularly, in step (2), the purification means to filter the original liquid medicine through an ultramicro filter membrane; in step (3), the filter is ultrafiltration membrane filter. Pre-extracted liquid medicine is effectively filtered through the ultramicro filter membrane so as to achieve nonalcoholic production, simplify technology, shorten production period, reduce energy consumption and production cost; meanwhile, prepared liquid medicine is subjected to terminal filtration through organic tubular type ultrafiltration membrane filtering technology so as to ensure the content of effective compositions, improve clarity of the liquid medicine, improve product quality, and ensure quality stability of the product.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a preparation process of a heat-clearing and detoxifying oral liquid. Background technique [0002] Qingrejiedu Oral Liquid is a traditional Chinese medicine liquid preparation refined from twelve herbs such as gypsum, honeysuckle, scrophulariaceae, rehmannia root, forsythia, gardenia, scutellaria baicalensis, scutellaria baicalensis, gentian, isatis root, zhi, and radix japonicus. It can clear away heat and detoxify, nourish yin and cool blood, reduce fever quickly, and the course of treatment is short without recurrence. It is used for fever, flushing, irritability and thirst, and sore throat caused by excessive heat and toxin. Influenza and upper respiratory tract infection see the above symptoms. Compared with similar drugs, this product has the following advantages: it has dual functions of antibacterial and antiviral at the same tim...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/00A61P29/00A61P11/00A61P11/04A61P31/16A61K33/06
Inventor 项振荣
Owner 苏州华辰净化股份有限公司
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