Synthesis method of dichloro tetrafluoroethoxy aniline

Abstract

The invention relates to a method for synthesizing dichlorotetrafluoroethoxyaniline. 3, 5-dichloro-p-aminophenol and tetrafluoroethylene are taken as raw materials to react, and a catalyst is one or two of potassium carbonate and potassium bicarbonate; and a solvent is formed by taking methylbenzene as a main body and adding an aprotic solvent which accounts for 1 to 5 percent of the total weightof the solvent. The method for synthesizing the dichlorotetrafluoroethoxyaniline takes weakly alkaline salt compounds as the catalyst; the alkalinity is relatively weaker, so the method has mild reaction and few side reactions, and effectively improves the conversion rate of the 3, 5-dichloro-p-aminophenol and the selectivity of the dichlorotetrafluoroethoxyaniline; moreover, the synthesis methodmainly takes the methylbenzene as the solvent, and can be directly used for the synthesis of a downstream product, namely hexaflumuron without performing displacement of the solvent after the reaction is finished, thereby shortening a process route, saving energy sources, reducing the drainage of wastewater, and protecting the environment.

Description

technical field [0001] The invention relates to a synthesis method of dichlorotetrafluoroethoxyaniline, in particular to a synthesis method using tetrafluoroethylene and 3,5-dichloro-p-aminophenol as raw materials and weakly basic salt compounds as catalysts. The method of dichlorotetrafluoroethoxyaniline. Background technique [0002] Hexaflumuron is a new type of fluorine-containing chemical pesticide widely used in the world, and hexaflumuron belongs to the benzoylurea insecticides. The main function is to inhibit the synthesis of chitin in insects and hinder the normal molt growth of insects. It is mainly stomach poisoning and also has contact killing effect. This unique insecticidal mechanism has attracted people's attention. It is different from traditional insecticides that target the nervous system. It overcomes the serious deficiency of traditional insecticides that are toxic to most animals and humans, and It can be decomposed by microorganisms, so authorities be...

AI Technical Summary

Problems solved by technology

This synthetic method is owing to adopt potassium hydroxide to make catalyzer, and alkali is too strong, and side reaction is more, and the conversion rate of 3,5-dichloro-p-aminophenol, dichlorotetrafluoroethoxyaniline selectivity are all relatively poor, 90% and 81% respectively

Causes a waste of resources and increases the difficulty of the three wastes treatment

The synthesis method of dichlorotetrafluoroethoxyaniline uses DMF as solvent, while the production process of hexaflumuron uses toluene as solvent, so in the production process of hexaflumuron, DMF must be replaced with toluene, which prolongs the process route and wastes energy , more waste water is produced during the replacement process, which brings great difficulties to environmental protection work

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