Application of components with activities of microbiological resistance and anti-inflammatory in nelumbo nucifer (nulumbo lutea) fruit (lotus seed)

A technology of antimicrobial and active ingredients, which is applied in the field of application of antimicrobial and anti-inflammatory active ingredients in the prevention and treatment of oral diseases, and can solve the problems of no extract, unused skin and core, little knowledge about biological activity and utilization, etc. , to achieve the effect of high content of active ingredients, outstanding health care and therapeutic effects, and good market prospects

Inactive Publication Date: 2009-12-23
湖北汇特生物医药技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, people have little research on the fruit part of the lotus seed plant, and its skin and core have never been used. Little is known about the biological activity and utilization of the fruit part of the lotus seed plant, and there is almost no active extract from it. thing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The buccal tablet containing antimicrobial and anti-inflammatory active ingredients of lotus seeds, the weight percentage of its components is:

[0020] Luo Han Guo (or its plants) antimicrobial active ingredients 15%

[0021] Lotus (Lotus) Fruit (Lotus Seed) Antimicrobial and Anti-inflammatory Active Ingredients 10%

[0022] Mogroside 1%

[0023] Mannitol 25%

[0024] Dextrin 10%

[0025] Menthol 0.5%

[0026] HPMC 4.0%

[0027] Magnesium Stearate 0.5%

[0028] Anhydrous ethanol amount

[0029] Preparation method: fully mix the antimicrobial active ingredient extract of Luo Han Guo (or its plant), lotus (lotus) fruit (lotus seed) antimicrobial and anti-inflammatory active ingredient extract, mogroside, mannitol, and dextrin in a prescribed amount, Sieve, dissolve the prescription amount of menthol in an appropriate amount of ethanol, and add it to the mixed powder. Use 2% HPMC solution as binder to make suitable soft material, granulate with 16 mesh sieve, gran...

Embodiment 2

[0032] The buccal tablet containing antimicrobial and anti-inflammatory active ingredients of lotus seeds, the weight percentage of its components is:

[0033] Luo Han Guo (or its plants) antimicrobial active ingredient 5%

[0034] Lotus (Lotus) Fruit (Lotus Seed) Antimicrobial and Anti-inflammatory Active Ingredients 5%

[0035] Mannitol 25%

[0036] Dextrin 20%

[0037] Menthol 0.5%

[0038] HPMC 4.0%

[0039] Magnesium Stearate 0.5%

[0040] Anhydrous ethanol amount

[0041] Preparation method: fully mix the antimicrobial active ingredient extract of Luo Han Guo (or its plant), lotus (lotus) fruit (lotus seed) antimicrobial and anti-inflammatory active ingredient extract, mannitol, and dextrin, and sieve the prescribed amount. Menthol is dissolved in an appropriate amount of ethanol and added to the mixed powder. Use 2% HPMC solution as binder to make suitable soft material, granulate with 16 mesh sieve, granulate with 14 mesh sieve after drying, add magnesium steara...

Embodiment 3

[0044] Containing the oral spray of lotus (fruit) fruit antimicrobial and anti-inflammatory active ingredients, the weight percentage of its component is:

[0045] Luo Han Guo (or its plants) antimicrobial active ingredients 15%

[0046] Lotus (Lotus) Fruit (Lotus Seed) Antimicrobial and Anti-inflammatory Active Ingredients 5%

[0047] Ethanol 10%

[0048]Glycerin 0.2%

[0049] Chlorhexidine 0.05%

[0050] Peppermint Oil 0.5%

[0051] Sodium Saccharin 0.03%

[0052] Add water to 100%

[0053] Preparation method: Dissolve chlorhexidine and peppermint oil in ethanol, and add appropriate amount of distilled water. Then add Luo Han Guo (or its plant) extract, lotus (lotus) fruit (lotus seed) extract, glycerin and sodium saccharin into the aqueous solution, stir evenly, add water to the full amount, filter, and put it in a spray storage bottle. .

[0054] Product Efficacy: This oral spray is antibacterial and anti-inflammatory, cools blood and relieves pain. It can be used...

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PUM

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Abstract

The invention discloses a method for applying a component with the activities of microbiological resistance and anti-inflammatory in nelumbo nucifer (nulumbo lutea) fruit (lotus seed) to preventing and treating oral cavity diseases, which comprises the following step of preparing extract with the activities of the microbiological resistance and the anti-inflammatory in the nelumbo nucifer (nulumbo lutea) fruit (the lotus seed) into a medicament, food and daily necessities with the functions of health care and treatment of an oral cavity, wherein the content of the extract in the products is 0.1 to 25 percent. The medicament with the function of treating the oral cavity can be made into a preparation in any form, such as tablets, spray, powder, film agents, paint, ointments, gels, gargle and the like; the food and the daily necessities having the function of dental care comprise chewing gum, beverage, tea, wine, toothpaste, tooth powder and the like; and the component with the activities with the microbiological resistance and the anti-inflammatory extracted from the nelumbo nucifer (nulumbo lutea) fruit (the lotus seed) is applied to the oral cavity diseases of a human, and develops medicaments, health care food and daily necessities for treating the oral cavity diseases, such as tooth decay, periodontitis, gingivitis, toothache, tooth haemorrhage, oral ulcer, bromopnea, pharyngitis, sore throat and the like. The method relates to the development and application of the component with the activities of the microbiological resistance and the anti-inflammatory in the nelumbo nucifer (nulumbo lutea) fruit (the lotus seed) to novel medicaments, the functional food, the daily necessities, the food additives and the like. The method has wide application prospect and important social benefit and economic benefit.

Description

technical field [0001] The present invention relates to the application of biologically active components of natural materials, in particular to the application method of antimicrobial and anti-inflammatory active components extracted from various lotus (lotus) fruits (lotus seeds) in preventing and treating oral diseases. Background technique [0002] Lotus (Nelumbo nucifer, Nelumbo lutea), family and genera: Nymphaeaceae, Nelumbo lutea. Perennial aquatic plants, herbaceous plants. The leaves are round, above the water surface, with long lotus stems, thorns, and grow in a shield shape. The rhizome (lotus root) is fat and multi-segmented, and grows horizontally in the bottom mud. The leaves are shield-shaped and round, the surface is dark green, the back is gray-green covered with waxy white powder, and the margin is entire and wavy. The flowers are solitary on the top of the pedicel and above the water surface. Nuts are oval or ovoid, commonly known as lotus seeds, 1.5 ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/62A61K9/20A61K9/12A61K9/14A61K9/10A61K9/06A61K9/00A61K9/46A61K8/97A23L1/29A23L1/30A23L2/52A23G4/12A23F3/34C12G3/04A61P1/02A61P11/04A61P31/00A61P29/00A61Q11/00A61K131/00
Inventor 黄赤夫周英余波
Owner 湖北汇特生物医药技术有限公司
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