Medicinal composition containing calcium channel blockers, ACE inhibitors and statins

Abstract

The invention relates to a medicinal composition, which comprises calcium channel blockers (CCB) or a mixture thereof, angiotensin-converting enzyme inhibitors (ACEI) or a mixture thereof, statins or a mixture thereof and a pharmaceutically acceptable carrier, wherein the calcium channel blockers are selected from levamlodipine, amlodipine, lacidipine, nitrendipine, or a mixture thereof; the angiotensin-converting enzyme inhibitors are selected from perindopril, ramipril, fosinopril, enalapril, or a mixture thereof; and the statins are selected from atorvastatin, simvastatin, rosuvastatin, fluvastatin, or a mixture thereof. The medicinal composition is used for treating various types of hypertension, treating or preventing cardio-cerebral vascular diseases related to the hypertension, reducing the incidence and / or the mortality of the cardio-cerebral vascular diseases and improving the medication compliance of patients.

Description

technical field [0001] The invention relates to a novel pharmaceutical composition, in particular to a pharmaceutical composition containing a calcium ion antagonist or a mixture thereof, an angiotensin-converting enzyme inhibitor or a mixture thereof, and a statin or a mixture thereof, belonging to the field of medicine . Background technique [0002] Due to the development of social economy and the change of people's lifestyle, the prevalence rate of hypertension in our country shows a continuous growth trend. According to the results of the national nutrition and health status survey in 2002, the prevalence rate of hypertension among adults in my country reached 18.8%. 160 million hypertensive patients. At present, one person dies of cardiovascular and cerebrovascular diseases every 15 seconds in my country, and the total morbidity and mortality of cardiovascular and cerebrovascular diseases are close to the level of developed countries. Statistics from the Ministry of H...

AI Technical Summary

Problems solved by technology

Although the compound preparation has an obvious antihypertensive effect and reduces cardiovascular morbidity and / or mortality, it is still unsatisfactory

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