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Drug for treating gynecological diseases and preparation technology thereof

A technology for gynecological diseases and drugs, which is applied in the field of drugs for treating gynecological diseases and its preparation process, drug preparation technology, and traditional Chinese medicine for treating gynecological diseases, and can solve the problem that antifungal drugs cannot be used for bacterial infectious diseases Short time at the lesion site, low utilization rate of drug ingredients, etc., to achieve the effects of low drug cost, reasonable prescription preparation, and concentrated drug action

Inactive Publication Date: 2010-01-13
王捷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the methods adopted for the treatment of bacterial vaginosis and fungal vaginitis mainly include two kinds of treatment methods, traditional Chinese medicine and western medicine. Western medicine is mainly oral medicine for the treatment of gynecological diseases. The treatment speed is fast, but the disadvantage is that the side effects are large, and it is easy to relapse after being cured, especially antibiotics are easy to make bacteria resistant, and antifungal drugs can not be used for bacterial infectious diseases
Oral Chinese medicine treatment of gynecological diseases has great advantages over western medicine in terms of toxic and side effects, but the current Chinese medicine raw materials for treating gynecological diseases have many components, generally as many as a dozen kinds, the preparation process is complicated, and the utilization rate of drug ingredients is relatively low
[0004] There is also a traditional Chinese medicine and western medicine lotion for the treatment of bacterial vaginosis and fungal vaginitis. This method has less side effects than oral medicine, and the medicine can also directly act on the lesion. However, because the medicine is a liquid structure, the medicine is attached to the lesion. The time of the site is relatively short, and it is necessary to continuously clean the lesion with drugs, which is very inconvenient to use

Method used

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  • Drug for treating gynecological diseases and preparation technology thereof
  • Drug for treating gynecological diseases and preparation technology thereof
  • Drug for treating gynecological diseases and preparation technology thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The raw material prescription is taken according to parts by weight (grams):

[0025] Phellodendron 300g Sophora flavescens 300g Kochia scoparia 200g

[0026] Agrimony 100g, borneol 5g.

[0027] The dosage form of the medicament made by the above prescription is a suppository.

[0028] The preparation process is as follows: in the above-mentioned five-flavored raw materials, take Phellodendron Phellodendron, Sophora Sophora, Kochia Kochia, and Agrimony four traditional Chinese medicine raw materials, respectively add 6 times the amount and 5 times the amount of 85% ethanol to reflux and extract twice, each time for 1.5 hours, and combine The extract is recovered from ethanol under reduced pressure until it has no alcohol smell, dried under reduced pressure, crushed into fine powder, added gradually to the melted mixed fatty acid glyceride matrix, then added borneol, stirred evenly, poured into a suppository mold, and obtained 100 Suppository medicine, to be taken out ...

Embodiment 2

[0033] The raw material prescription is taken according to parts by weight (grams):

[0034] Phellodendron 350g Sophora flavescens 350g Kochia scoparia 250g

[0035] Agrimony 110g borneol 8g.

[0036] The preparation process is the same as in Example 1.

[0037] The name of the product produced by the present invention is: Baixian Fuyan suppository

[0038] The main pharmacodynamics test of the medicine Baixianfuyan suppository produced by the present invention

[0039] Objective: To investigate the pharmacodynamics of Baixianfuyan suppository.

[0040] Methods: 1. In vitro antibacterial test of Baixianfuyan suppository against common vaginal infection bacteria: the MIC of Baixianfuyan suppository was determined by dish flat double-and-a-half incorporation method.

[0041] 2. The effect of Baixian Fuyan Suppository on mycotic vaginitis in rabbits: Inject Candococcus albicans bacteria liquid into the rabbit vagina to form a model of mycotic vaginitis in rabbits. After the m...

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Abstract

The invention relates to a drug for treating gynecological diseases and a preparation technology thereof, belonging to the technical field of drug manufacture and including the preparation technology of the drug. The components of the main raw materials are characterized by: 30-350 parts of bark of chinese corktree, 30-350 parts of lightyellow sophora root, 20-250 parts of fructus kochiae, 10-110 parts of Hairyvein Agrimonia Herb and Bud and 1-8 parts of borneol. The raw materials are mixed to be prepared into a suppository dosage form through ethanol extraction. When in use, the active ingredients of the drug can reach the focus directly, therefore the drug has strong pertinence and concentrated acting force and causes no irritation and very little toxic or side effect to the digestive system of human body after use. The drug has few raw materials and simple preparation technology, and is proved to have rather obvious effect of treating bacterial vaginosis and colpomycosis by die pharmakodynamik experiments, as well as the functions of clearing heat and drying dampness, killing insects and relieving itching.

Description

1. Technical field [0001] The invention relates to a traditional Chinese medicine for treating gynecological diseases, in particular to a medicine for treating gynecological diseases and a preparation process thereof, belonging to the technical field of medicine manufacturing, including the preparation process of the medicine. 2. Background technology [0002] Bacterial vaginosis and fungal vaginitis are common and frequently-occurring diseases in TCM gynecology. Since the vagina is connected to the outside world, vaginal infections are often caused by factors such as menstruation or sexual life, or factors such as childbirth and uterine operations, and even inflammation can invade the internal organs. genitals, leading to pelvic inflammatory disease. In addition, people suffering from diabetes, vitamin B deficiency, ovarian function decline, certain allergies or infectious diseases are more susceptible to infection. In recent years, the incidence has been on the rise. Heav...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P15/02A61P15/00A61P31/10A61P31/04A61K31/045
Inventor 王捷
Owner 王捷
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