Water soluble puerarin derivatives and preparation method and application thereof

A technology of puerarin derivatives and puerarin, which is applied in the direction of sugar derivatives, chemical instruments and methods, compounds of group 5/15 elements of the periodic table, etc., and can solve problems such as unstable preparations and poor water solubility of puerarin
CN101712676AActive Publication Date: 2010-05-26SHENZHEN JYMED TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENZHEN JYMED TECH
Publication Date
2010-05-26

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Abstract

The invention discloses water soluble puerarin derivatives shown in general formulas (I) and (II), a preparation method thereof, a medicinal composition containing one or more compound compositions, and application of the compounds in preparing medicaments for treating diseases such as cardiovascular and cerebrovascular diseases, retinal artery and vein occlusions, diabetes and the like.
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Description

technical field

[0001] The invention relates to puerarin, in particular to a water-soluble puerarin derivative and a preparation method and use thereof. Background technique

[0002] Puerarin is a flavonoid glycoside extracted from the dried root of the perennial leguminous plant Pueraria lobata (Willd.) Ohwi or Pueraria thomsonii Benth. The chemical name is 7,4'-dihydroxy-8-β-D-glucose isoflavone, and the molecular formula is C 21 h 20 o 9 , molecular weight 416.38, CAS number 82373-94-2; as a unique component of kudzu root, it has a unique chemical structure, biological activity and pharmacological effects. Puerarin has the effect of dilating coronary arteries and cerebrovascular, has the functions of lowering blood sugar, blood fat, anti-oxidation, and improving hemorheology characteristics, so it is widely used in the treatment of clinical hypertension, coronary heart disease, acute cerebral infarction, diabetes and other diseases.

[0003] The solubility of puerarin...

Claims

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