Wide field of view optical coherence tomographic instrument based on adaptive optical technology

Abstract

The invention relates to a wide field of view optical coherence tomographic instrument based on the adaptive optical technology, which comprises an optical source assembly, a reference arm assembly, an aberration detecting and correcting assembly, a two-dimensional imaging and scanning assembly, a wide field of view scanning assembly and a detector assembly. In the optical coherence tomographic instrument provided by the invention, an optical signal receiving part of a system mainly utilizes optical fibers and optical fiber couplers, so that the system has compact design. A lighting optical path part is designed by mainly using spherical reflector telescopes, so that the higher order aberration of the system is avoided. Meanwhile, the adaptive optical technology is introduced to detect and correct wave-front aberration, so that the light beam quality of the lighting optical path and an imaging optical path both achieve the level of diffraction limits. Through the synchronous operation of a fast tilting mirror and the two-dimensional imaging and scanning assembly, the high-resolution tomographic image of the human eye ground (or a sample to be measured) in a wide field of view range by using the automatic mosaic technology on the basis of the acquisition of a small field of view single-frame image. The invention mainly solves the difficulty of high-resolution and wide field of view synchronous imaging, the wide field of view optical coherence tomographic instrument with compact design and high imaging resolution and wide imaging field of view is realized, and the imaging field of view and the imaging quality of the traditional optical coherence tomographic instrument are greatly improved.

Description

technical field [0001] The invention relates to a biological or medical tomography instrument, in particular to a wide-field optical coherence tomography based on adaptive optics technology, which can perform high-resolution optical coherence tomography on biological tissues within a large field of view imaging. Background technique [0002] A.F.Fercher et al. proposed earlier to measure the length of the eye axis by the method of interferometric imaging (A.F.Fercher et.Al "Eye-length measurement by interferometry with partially coherent light", Optics Letters.13, 186-188 (1998)), which Later, David Huang et al. did more research on the development of OCT technology (Huang D et al. Laser Surg Med 1991.11: 5). [0003] The invention patent with the patent number US5825533 (1998) proposes to carry out horizontal and vertical synchronous scanning through two independent scanning galvanometers to realize confocal scanning imaging. This patent gives the basic principle of two-d...

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Problems solved by technology

[0006] The technology of the present invention solves the problem: to overcome the limitation that traditional optical coherence tomography cannot realize simultaneous imaging of high resolution and large field of view at the same time, a wide field of view optical coherence tomography based on adaptive optics technology is proposed to obtain the human eye (or the objective lens and the sample to be imaged, the same below) high-resolution tomography within a large field of view

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