Preparation method of fructose diphosphate sodium powder injection

A technology of sodium fructose diphosphate and powder injection, which is applied in the field of drug preparation, can solve problems such as unfavorable storage and transportation, influence of drug effect, poor stability, etc., and achieve the effects of saving resources, improving drug stability and mild process conditions
CN101953793AInactive Publication Date: 2011-01-26SHANGHAI NEW ASIA PHARMA +2
0 Cites 14 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI NEW ASIA PHARMA
Publication Date
2011-01-26
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a preparation method of a fructose diphosphate sodium powder injection, comprising the following steps of: decoloring, degerming, roughly filtering and finely filtering a fructose diphosphate sodium water solution; and punching, separating and crystallizing with ethanol or acetone and filling to obtain the aseptic powder injection. The fructose diphosphate sodium powder injection prepared by the method has higher purity, fewer impurities and more stable quality compared with the traditional products and is convenient to store and transport. The invention is simple to operate, has mild process condition and low cost and is suitable for industrial production.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the technical field of medicine preparation. Specifically relates to a preparation method of sodium fructose diphosphate powder for injection. Background technique

[0002] Sodium fructose diphosphate is an adjuvant therapeutic drug for myocardial ischemia. It is an intermediate product of glucose metabolism in the body. It produces pharmacological effects by regulating the activity of several enzymes in glucose metabolism. Exogenous fructose 1,6-diphosphate can increase the concentration of intracellular adenosine triphosphate and creatine phosphate, promote the influx of potassium ions, increase the content of diphosphoglycerate in red blood cells, inhibit the release of oxygen free radicals and histamine, etc. It can reduce the damage caused by ischemia and hypoxia, especially for ischemic heart disease. Sodium fructose diphosphate is basically the same as glucose, which has the effect of directly supplying heat energy, re...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More