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Gargle for treating periapicalitis

A technique for periapical periodontitis and gargle, which is applied in the field of medicine, can solve the problems of high cost of western medicine treatment, great gastrointestinal irritation, western medicine allergy and the like, and achieves the effects of obvious curative effect, simple ingredients and easy-to-obtain ingredients.

Inactive Publication Date: 2011-04-06
张会茯
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1. Some patients are allergic to western medicines such as penicillin, spiramycin, and metronidazole
[0005] 2. Some patients have poor curative effect when using targeted western medicines such as penicillin and spiramycin
[0006] 3. Western medicine is more irritating to the stomach
[0008] 5. The treatment cost of some western medicine is too expensive
But the search for more rational drugs never stops

Method used

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  • Gargle for treating periapicalitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Weigh 50 grams of raw land, 30 grams of Panax notoginseng, 30 grams of angelica, 100 grams of Prunella vulgaris, 50 grams of comfrey, 200 grams of honeysuckle, 200 grams of coptis, 50 grams of rhubarb, 200 grams of Gentiana, 50 grams of Chuanxiong, 50 grams of Angelica dahurica and water 800 grams, placed in a sealed flask, heated in a water bath at 50°C for 5 hours, filtered, and the filtrate collected, sterilized to obtain the final product.

experiment example 1

[0018] Refer to "Journal of Hebei Traditional Chinese Medicine", volume 23, phase 4, the method disclosed on pages 30-31 to measure the in vitro antibacterial activity of the gargle of the present invention. The test strains Pg (PgATTCC33277), Pi (PiATCC25611), and Aa (FnATTCC24523) used therein can be purchased from Nanjing Jiancheng Bioengineering Institute. And for the purpose of scientific research, it can be released to the public within 20 years from the date of this application.

[0019] Preparation of anaerobic bacteria suspension

[0020] The strains were inoculated on the anaerobic blood plate, and the anaerobic environment was recovered for 48 hours at 37°C (80% N 2 , 10%H 2 , 10% CO 2 ). After recovery, the preserved strains were inoculated on CDC anaerobic blood agar plates. Pick the bacterium colony on the surface of the agar and suspend it in the prepared sterilized Steiner's broth medium, and after cultivating for a corresponding time (48h), the concentrat...

experiment example 2

[0033] Experimental Example 2: Patient's Taste and Taste

[0034] Please 10 patients use the gargle of embodiment 1. 10 patients all indicated that the mouthfeel of this gargle was good. Six of them were swallowed by the patient without any advice or suggestion. After asking all 10 patients to swallow, they all indicated that the taste of the gargle was good.

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Abstract

The invention relates to a gargle for treating periapicalitis, which is prepared from the following components in parts by weight: 1-10 parts of root of rehmannia, 1-5 parts of pseudo-ginseng, 1-5 parts of angelica, 5-10 parts of selfheal, 1-5 parts of Chinese gromwell, 10-30 parts of honeysuckle, 10-30 parts of rhizoma coptidis, 1-10 parts of rheum officinale, 10-30 parts of gentiana macrophylla, 1-10 parts of rhizoma ligustici wallichii, 1-5 parts of dahurian angelica and 500-1000 parts of water. The gargle for treating periapicalitis of the invention has simple and easily-obtained contents and remarkable curative effect, thereby providing a new selection for clinically treating the periapicalitis.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a gargle for treating periapical periodontitis. Background technique [0002] Periodontal periodontitis is a chronic infectious disease of periodontal support tissue caused by anaerobic bacteria. Inhibiting and killing pathogenic bacteria plays an important role in the treatment and prevention of periodontitis. Studies have shown that Porphyrobacter gingivalis (Pg) is a well-documented pathogen of periodontitis, while Prevotella intermedia (Pi) is a moderately associated pathogen of apical periodontitis, with Actinobacillus actinomycetes (Aa) Is the main pathogenic bacteria of juvenile periodontitis. [0003] At present, antibiotics and western medicines are commonly used in the treatment of periodontitis, but the following shortcomings are found clinically: [0004] 1. Some patients are allergic to western medicines such as penicillin, spiramycin, and metronidazole. [0005] 2. Some p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/00A61P1/02A61P31/04
Inventor 徐保东
Owner 张会茯
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