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Disinfecting active film as well as preparation method and application thereof

A film and active technology, applied in the field of medical devices, can solve the problems that bacteria and viruses do not have a broad spectrum, affect the comfort and breathability of use, and the targeted efficiency is uncertain, etc., to achieve effective filtration and elimination, High safety and low cost effect

Inactive Publication Date: 2011-05-18
上海普天欣生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent 94107134.0 introduces masks with activated carbon fiber and traditional Chinese medicine protective layer or chemical protective layer. On the one hand, it affects the comfort and breathability of use. In addition, the effect of traditional Chinese medicine on bacteria and viruses does not have a broad spectrum.
Chinese patent 01264442.0 uses nanofibers, the cost is high, and the targeted efficiency is still uncertain

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0026] Example 1: Add 64 g of polytetrahydrofuran diol with a relative molecular mass of 2000 and 51.2 g of polyethylene glycol with a relative molecular mass of 80 into a four-necked flask, seal it and pass nitrogen gas at 120° C. for 1.5 hours to remove water. At 65°C, under normal pressure, 25.7 g of isophorone diisocyanate and 20 g of methyl ethyl ketone were added, and the mixture was reacted at 85°C for 4 hours. Then, 40 g of a butanone solution containing 3.48 g of ethylenediamine was added. React for 2 hours. The butanone solvent was removed under reduced pressure at 70°C, and the material was discharged. The crude product was moved to a vacuum drying oven, and dried at 100° C. and a vacuum degree of 0.5 MPa for 24 hours to obtain a polyurethane pressure-sensitive adhesive. Then 10 g of polyurethane pressure-sensitive adhesive and 10 g of 5% ethanol solution of ribavirin are mixed evenly at 80° C. and coated on the non-woven fabric.

Embodiment 2

[0028] Add 40 g of polyoxypropylene diol with a relative molecular mass of 2000 and 100 g of polyethylene glycol with a relative molecular mass of 1000 into a four-necked flask, seal it and ventilate nitrogen at 120° C. for 2 hours to remove water. At 65°C, under normal pressure, 70 g of 1,6-hexamethylene diisocyanate and 70 g of butanone were added, and the mixture was reacted at 85°C for 4 hours. Add ethylenediamine / butanone mixed solution (2.62 g of ethylenediamine, 30 g of butanone), and react for 2 hours. The butanone solvent was removed under reduced pressure at 70°C, and the material was discharged. The crude product was moved to a vacuum drying oven, and dried at 100° C. for 24 hours under a vacuum degree of 0.1 MP to obtain a polyurethane pressure-sensitive adhesive. Then 10 g of polyurethane pressure-sensitive adhesive and 10 g of 1% ethanol solution of zanamivir were mixed uniformly at 80° C., and coated on the polyvinyl chloride film.

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PUM

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Abstract

The invention relates to the technical field of medical apparatus and instruments, and in particular relates to a disinfecting active film capable of being fixed on any solid phase surface and eliminating pathogens as well as a preparation method and an application thereof. The disinfecting active film is prepared from polyurethane which is made of random placed polyether of isocyanate, polyethylene glycol and an amine chain extender or a polymer of the amine chain extender. The disinfecting active film is characterized in that the polyurethane contains or is loaded with antiviral drugs or / and antibacterial drugs. The disinfecting active film has the advantages of low cost, no toxicity and harmlessness and high efficiency, has no influence on ventilation, and can effectively filter and eliminate pathogenic microorganisms under the physical effect and drug action, thus playing an important role in preventing communicable diseases of respiratory tract and gastrointestinal tract, and having huge social and economic benefits.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a disinfectant active film capable of fixing and removing pathogens and its preparation method and application. Background technique [0002] Masks are closely related to our lives. Masks are mainly used to filter suspended solids in the air to purify the air that people inhale. In order to prevent external harmful substances from entering the respiratory system, the functions of general masks can be divided into two types. One is to avoid passive infection (such as the N95 masks produced by Megatech Scientific Co., Ltd. in the United States and the FFP1 and FFP2 masks passed by the European Union. Masks cannot prevent active infection); the other can prevent the infected person from transmitting the virus to others (such as medical surgical masks). None of these methods can effectively filter pathogenic microorganisms such as viruses, because the size of viruses is only...

Claims

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Application Information

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IPC IPC(8): A61L9/00A41D13/11
Inventor 熊乾斌俞正威苏虎苏勇
Owner 上海普天欣生物技术有限公司