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Eye protection patches and preparation process thereof

An eye patch and eye technology, which is applied in the directions of sheet delivery, medical preparations with non-active ingredients, active ingredients of hydroxyl compounds, etc., can solve the problems of impossible nutrients, unclear main ingredients, and easy flow of medicinal liquids, etc. Achieving the effect of large drug loading, good compatibility and no skin allergy

Inactive Publication Date: 2011-07-27
候玉庆 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the main ingredient is not clear, it is impossible to contain transdermal fat-soluble eye nutrition ingredients, and the liquid medicine of the water-soluble film itself is easy to flow, lose volatilization, and take a posture of looking up, which has caused some inconvenience to the user.

Method used

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  • Eye protection patches and preparation process thereof
  • Eye protection patches and preparation process thereof
  • Eye protection patches and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Preparation of juvenile eye protection patch: The preparation process adopts the method of preparing the raw liquid medicine and the matrix material separately.

[0022] Preparation of raw material liquid: first weigh 0.1-1% borneol and 0.1-1% cooling agent and grind into fine powder, then take 1-5% lutein, 1-5% DHA, 0.1-2% vitamin A palmitic acid Esters, 0.1-2% vitamin C palmitate, 1-10% azone, 1-10% high-grade olive oil, etc. Stir and mix the above solutions. Stir the prepared raw material medicine solution repeatedly for another 10-20 minutes, and set aside.

[0023] Preparation of matrix material: styrene-isoprene-styrene block copolymer (SIS) 1-75%, plasticizer 1-65%, tackifier 1-35%, antioxidant 0.1-3.5 %, react at a high temperature of 100-200°C for 0-5 hours to make a matrix material suitable for human eye skin. After cooling the glue block, set aside.

[0024] Preparation method: Put the raw drug solution and matrix material into the quantitative drug admini...

Embodiment 2

[0026] Embodiment 2: Application of eye protection patch

[0027] The new eye protection patch made by the above method was compared with the water-soluble eye protection patch of commercially available general non-woven fabric soaked in traditional Chinese medicine extract as follows.

[0028] 1. Comparison of skin irritation:

[0029] The experimental animals were white rabbits, 20 in each group. The new eye protection patch and the water-soluble eye protection patch were applied to the eye skin respectively. The application time was 48 hours. The experimental results are shown in Figure 2. Skin irritation Compare chart.

[0030] As shown in Figure 2, on the white rabbits used in the experiment, the water-soluble eye protection patch showed strong skin irritation after 48 hours of application, while the skin irritation of the new eye protection patch was almost zero.

[0031] 2. Comparison of transdermal absorbability:

[0032] The in vitro transdermal absorption of lutei...

Embodiment 3

[0035] The samples produced in Example 1 were subjected to biomechanical measurements to determine the requirements for adapting to the eyes of the human body, especially the requirements for initial adhesion, holding force and peeling force of the delicate skin around the eyes. The results are shown in Table 1.

[0036] Table 1: Cosmetic patch performance test results

[0037] Initial viscosity (ball number)

[0038] After volunteers tried this patented product, it not only has good curative effect, but also is soft and elastic, does not cause eye skin lifting pain, can be pasted repeatedly, and has no irritation and allergies.

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Abstract

The invention discloses external patches which adapt to eye nutrition and health care of people in different ages and contain abundant nutrient components required by eyes such as lutein and the like. A novel elastomer material, namely styrene-isoprene-styrene block copolymer (SIS) is taken as a framework material. Various external eye patches for the people in the different ages are prepared by a low temperature on-line melting molding technology. Patented products are external eye nutrient patches which have specific components, exact functions and soft texture, easily penetrate skin, are highly elastic, and can be persistently released.

Description

technical field [0001] The invention relates to an eye protection patch using a novel elastomer material-styrene-isoprene-styrene block copolymer (SIS) matrix material and a preparation method thereof, belonging to the field of skin care products. Background technique [0002] The eyes are the most important organ in the human senses, and about half of the knowledge and memory in the brain are obtained through the eyes, which distinguish different colors and lights, and then convert these visions or images into nerve signals and transmit them to the brain . In this learning society and a world full of fluorescent screens, unscientific use of eyes and the influence of electronic radiation have had a great impact on people of different ages, and there are eye diseases. The incidence of myopia among primary and middle school students is close to 60%, ranking first in the world. The eye health of children and adolescents has received more and more attention from the society. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K31/047A61K47/32A61P27/10A61P27/00
Inventor 候玉庆史关正
Owner 候玉庆
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