Method for continuous fractional separation and purification of effective ingredients of star anise

Abstract

The invention discloses a method for continuous fractional separation and purification of effective ingredients of star anise, and relates to purification of a natural product of star anise. The invention provides a method for continuous fractional separation and purification of the effective ingredients of the star anise, which can ensure the extraction efficiency of a target product, has low production operating cost, high solvent recovery rate and obviously low energy consumption, and is suitable for large-scale production. The method comprises the following steps of: extracting star aniseoil; extracting star anise oil resin; separating anethole from anisaldehyde; performing microbial conversion on shikimic acid; and extracting and separating the shikimic acid. On the basis of extracting the star anise oil resin and separating the anethole from the anisaldehyde, the shikimic acid is extracted and separated from extraction residue, products with high added value, such as shikimi fruit, the anethole and the anisaldehyde are obtained, and the extraction efficiency of the target product is ensured.

Description

technical field [0001] The invention relates to the extraction and purification of natural product star anise, in particular to a method for continuous fractionation and purification of star anise active ingredients. Background technique [0002] 1. Star anise oil and star anise oleoresin [0003] The volatile components in star anise are generally aromatic oils, fatty oils and other substances. Fresh or dried star anise fruit is used to extract aromatic oil, which is called fennel oil, anise oil or star anise oil. The extraction methods mainly include steam distillation, organic solvent extraction and supercritical extraction. Star anise oleoresin is a mixture of aromatic oils, fatty oils and resinous substances, and is generally produced by organic solvent extraction. At present, there are few reports about the simultaneous extraction of star anise oil and star anise oleoresin by distillation and extraction. [0004] (1) Steam distillation method. Steam distillation is...

AI Technical Summary

Problems solved by technology

[0010] (1) Conventional distillation relies on the difference in boiling points of different substances in the material mixture for separation, so the material liquid must be heated to boiling; in the traditional distillation process, due to the long heating time and high temperature, it is easy to cause molecular rearrangement and oxidation , hydrolysis or even polymerization, the aroma components will be destroyed

[0011] (2) Although conventional vacuum distillation can increase the vacuum degree, it will cause certain resistance due to the trays inside it, and it is difficult for the system to obtain a high vacuum degree

At present, there are very few research reports on this new way to obtain shikimic acid by bacterial transformation of star anise industrial extraction residue