Self-heated traditional Chinese medicine (TCM) emplastrum for lowering lipid and losing weight
A lipid-lowering weight loss, self-heating technology, which is applied in the directions of heating appliances, drug combinations, and pharmaceutical formulations for treatment and treatment, can solve the problems of excessive drug taste, unsatisfactory transdermal absorption, and complexity.
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Embodiment 1
[0055] 1. Preparation of plaster:
[0056] Prescription of raw materials: menthol 8g, tangerine peel 60g, cassia 92g, radish seed 80g, hawthorn 80g, Alisma 80g.
[0057] Matrix formula: 31g gelatin, 12g sodium carboxymethylcellulose, 8g polyvinyl alcohol, 88g pressure-sensitive adhesive, 24g carbomer, 250g glycerol, 250g propylene glycol, 8g kaolin, 8g zinc oxide, 9g citric acid, citric acid Sodium 33g, water 285g.
[0058] Preparation of water extract: take tangerine peel, cassia, radish, hawthorn and Alisma, add water and decoct twice, add 6 times the amount of water for the first time, add 6 times the amount of water for the second time, each time for 1.5 hours, combine The second decoction is filtered, the filtrate is concentrated to a thick paste with a relative density of 1.28-1.32 (measured at 60°C), dried at 80°C, crushed into fine powder, and sieved to obtain the product.
[0059] Preparation of active ingredients: adding menthol to the prepared water extract and mi...
Embodiment 2
[0067] 1. Preparation of plaster:
[0068] Prescription of raw materials: menthol 6g, tangerine peel 54g, cassia 93g, radish seed 77g, hawthorn 93g, alisma 77g.
[0069] Matrix formula: 37g gelatin, 14g sodium carboxymethylcellulose, 10g polyvinyl alcohol, 307g glycerol, 306g propylene glycol, 50g polyethylene glycol, 50g butanediol, 6g zinc oxide, 6g micronized silica gel, 29g sodium citrate , aluminum trichloride 8g, water 177g.
[0070] Preparation of water extract: same as Example 1.
[0071] Preparation of active ingredients: adding menthol to the prepared water extract and mixing evenly to obtain Chinese medicine extract powder.
[0072] Preparation of plaster: dissolve the prepared active ingredients in water, add propylene glycol, glycerin, polyethylene glycol and butylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, fully swell, Component 1 is obtained; sodium carboxymethyl cellulose is dissolved in 1 / 6 o...
Embodiment 3
[0079] 1. Preparation of plaster:
[0080] Raw material prescription: 10g menthol, 40g tangerine peel, 74g cassia, 74g radish, 92g hawthorn, 110g alisma.
[0081] Matrix formula: 40g gelatin, 17g sodium carboxymethylcellulose, 17g methylcellulose, 11g sodium polyacrylate, 11g polyvinyl alcohol, 11g polyvinylpyrrolidone, 125g pressure-sensitive adhesive, 33g carbomer, 156g glycerol, Propylene glycol 156g, micropowder silica gel 8g, citric acid 15g, sodium citrate 27g, water 373g.
[0082] Preparation of water extract: same as Example 1.
[0083] Preparation of active ingredients: adding menthol to the prepared water extract and mixing evenly to obtain Chinese medicine extract powder.
[0084] Preparation of plaster: dissolve the prepared active ingredients in water, add glycerol and propylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, and fully swell to obtain component 1; gelatin, carboxylate Sodium methyl cellu...
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