Self-heated traditional Chinese medicine (TCM) emplastrum for lowering lipid and losing weight

A lipid-lowering weight loss, self-heating technology, which is applied in the directions of heating appliances, drug combinations, and pharmaceutical formulations for treatment and treatment, can solve the problems of excessive drug taste, unsatisfactory transdermal absorption, and complexity.

Active Publication Date: 2012-03-07
佛山市慕姿服饰有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The patent application with the publication number CN101167906A discloses a pharmaceutical composition for reducing fat and reducing weight. An oral preparation made of two traditional Chinese medicines, it can benefit qi and invigorate the spleen, promote blood circulation and remove blood stasis, widen the chest and remove stagnation, lighten the body and reduce fat. It has obvious effects in simple obesity, but it is an oral preparation, which inevitably has a first-pass effect
[0005] The patent application of the patent application of publication number CN101485865A discloses a kind of " traditional Chinese medicine slimming patch ", and this medicine is made of Rad

Method used

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  • Self-heated traditional Chinese medicine (TCM) emplastrum for lowering lipid and losing weight
  • Self-heated traditional Chinese medicine (TCM) emplastrum for lowering lipid and losing weight

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] 1. Preparation of plaster:

[0056] Prescription of raw materials: menthol 8g, tangerine peel 60g, cassia 92g, radish seed 80g, hawthorn 80g, Alisma 80g.

[0057] Matrix formula: 31g gelatin, 12g sodium carboxymethylcellulose, 8g polyvinyl alcohol, 88g pressure-sensitive adhesive, 24g carbomer, 250g glycerol, 250g propylene glycol, 8g kaolin, 8g zinc oxide, 9g citric acid, citric acid Sodium 33g, water 285g.

[0058] Preparation of water extract: take tangerine peel, cassia, radish, hawthorn and Alisma, add water and decoct twice, add 6 times the amount of water for the first time, add 6 times the amount of water for the second time, each time for 1.5 hours, combine The second decoction is filtered, the filtrate is concentrated to a thick paste with a relative density of 1.28-1.32 (measured at 60°C), dried at 80°C, crushed into fine powder, and sieved to obtain the product.

[0059] Preparation of active ingredients: adding menthol to the prepared water extract and mi...

Embodiment 2

[0067] 1. Preparation of plaster:

[0068] Prescription of raw materials: menthol 6g, tangerine peel 54g, cassia 93g, radish seed 77g, hawthorn 93g, alisma 77g.

[0069] Matrix formula: 37g gelatin, 14g sodium carboxymethylcellulose, 10g polyvinyl alcohol, 307g glycerol, 306g propylene glycol, 50g polyethylene glycol, 50g butanediol, 6g zinc oxide, 6g micronized silica gel, 29g sodium citrate , aluminum trichloride 8g, water 177g.

[0070] Preparation of water extract: same as Example 1.

[0071] Preparation of active ingredients: adding menthol to the prepared water extract and mixing evenly to obtain Chinese medicine extract powder.

[0072] Preparation of plaster: dissolve the prepared active ingredients in water, add propylene glycol, glycerin, polyethylene glycol and butylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, fully swell, Component 1 is obtained; sodium carboxymethyl cellulose is dissolved in 1 / 6 o...

Embodiment 3

[0079] 1. Preparation of plaster:

[0080] Raw material prescription: 10g menthol, 40g tangerine peel, 74g cassia, 74g radish, 92g hawthorn, 110g alisma.

[0081] Matrix formula: 40g gelatin, 17g sodium carboxymethylcellulose, 17g methylcellulose, 11g sodium polyacrylate, 11g polyvinyl alcohol, 11g polyvinylpyrrolidone, 125g pressure-sensitive adhesive, 33g carbomer, 156g glycerol, Propylene glycol 156g, micropowder silica gel 8g, citric acid 15g, sodium citrate 27g, water 373g.

[0082] Preparation of water extract: same as Example 1.

[0083] Preparation of active ingredients: adding menthol to the prepared water extract and mixing evenly to obtain Chinese medicine extract powder.

[0084] Preparation of plaster: dissolve the prepared active ingredients in water, add glycerol and propylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, and fully swell to obtain component 1; gelatin, carboxylate Sodium methyl cellu...

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Abstract

The invention relates to a traditional Chinese medicine (TCM) compound preparation, in particular to a self-heated TCM emplastrum for lowering lipid and losing weight. The self-heated TCM emplastrum comprises a sealing bag, a plaster and a self-heated bag, wherein the plaster and the self-heated bag are wrapped in the sealing bag and are bonded together up and down; the self-heated bag comprises an air-permeable bag and chemical heating materials which are wrapped in the air-permeable bag and are used for iron oxidation-reduction reactions; and the plaster comprises a backing layer, a medicine storage layer and an anti-adhesion layer. The emplastrum is characterized in that the medicine storage layer comprises a pharmaceutically acceptable matrix and active ingredients of raw medicines; the active ingredients account for 40% of the matrix by weight and comprise 1.5-3% of menthol and aqueous extracts of the following raw medicines according to the weight percent of the raw medicines: 10-40% of dried orange peel, 10-50% of semen cassiae, 10-30% of semen raphani, 10-30% of hawthorn and 10-30% of rhizoma alismatis. The self-heated TCM emplastrum provided by the invention has the advantages of high effect taking speed, good percutaneous absorption and definite curative effect.

Description

field of invention [0001] The invention relates to medical preparations, in particular to a traditional Chinese medicine compound preparation. technical background [0002] Obesity refers to a certain degree of obvious overweight and thick fat layer, which is a state caused by excessive accumulation of body fat, especially triglycerides. Excessive body fat accumulation due to excessive food intake or changes in body metabolism results in excessive weight gain and causes human pathology, physiological changes or latency. The understanding of obesity in traditional Chinese medicine has been recorded for a long time, and its causes are mostly related to "dampness, phlegm, and deficiency". Traditional Chinese medicine believes that obesity is mostly a disease of deficiency in origin and excess in superficiality. The main deficiency is Qi deficiency. If both Yin and Yang are imbalanced, there may be Yang deficiency or Qi Yin deficiency. The disease is in the spleen, kidney, liv...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61K9/70A61F7/03A61P3/04A61P3/06
Inventor 方永奇方惠新刘林薛中锋方若鸣
Owner 佛山市慕姿服饰有限公司
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