Dendrobium traditional Chinese medicine composition, preparation method and application thereof

A composition, the technology of dendrobium, applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve problems such as difficult to guarantee product efficacy, affect clinical use, and unclear effective substances, so as to enhance non-specific immune function and restore bone marrow hematopoiesis function, and the effect of improving the bone marrow microenvironment

Active Publication Date: 2012-03-21
JIUXIANZUN HUOSHAN DENDROBIUM CO LTD
View PDF1 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the 1950s, TCM treatment of aplastic anemia has been roughly divided into three stages. Before the 1960s, it was mainly based on nourishing the heart and spleen or nourishing qi and blood; , almost all focus on invigorating the kidney, or at the same time nourishing qi and blood, or at the same time, or at the same time, or at the same time, or at the same time, or at the same time, or at the same time, or at the same time, or at the same time, or at the same time, or at the same time. There are many empirical prescriptions, but most of them are simple decoctions and self-made medicines. There are not many medicines standardized and developed according to the new drug standards. At present, there are mainly traditional Chinese medicines such as Compound Zaofan Pills and Xuebao Capsules on the market. , but the process is simple, the dosage form is backward, there are dozens of medicinal flavors, the active substance is not clear, the quality control technology content is low, the patient is inconvenient to take it, and the compliance is poor. It is difficult to guarantee the efficacy of the product, which affects clinical use.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Dendrobium traditional Chinese medicine composition, preparation method and application thereof
  • Dendrobium traditional Chinese medicine composition, preparation method and application thereof
  • Dendrobium traditional Chinese medicine composition, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Embodiment 1: hard capsule

[0014] 1. Raw materials: 125 grams of dendrobium, 250 grams of tortoise shell, 125 grams of Panax notoginseng.

[0015] 2. Preparation method: After the above three flavors are ultrafinely pulverized, mix them with 5g of microcrystalline cellulose, put them into capsules, and make 1000 capsules.

[0016] 3. Properties: This product is a hard capsule, and the content is a brown powder with a slight gas and a slightly bitter taste.

[0017] 4. Specifications: 0.5 grams per capsule.

[0018] 5. Usage and dosage: take orally. 4 capsules at a time, 2 times a day.

Embodiment 2

[0019] Embodiment 2: Granules

[0020] 1. Raw materials: 166.7 grams of dendrobium, 333.3 grams of tortoise shell, 166.7 grams of Panax notoginseng.

[0021] 2. Preparation method: After the above three flavors are ultrafinely pulverized, mix with 1111g dextrin and 222.2g powdered sugar, make granules, dry, and make 1000g, to get final product.

[0022] 3. Properties: This product is a granule, the content is brown granules, slightly gas, sweet and slightly bitter.

[0023] 4. Specifications: 3 grams per bag

[0024] 5. Usage and dosage: take orally. 1 bag at a time, 2 times a day.

Embodiment 3

[0025] Embodiment 3: tablet

[0026] 1. Raw materials: 83.3 grams of dendrobium, 166.7 grams of tortoise shell, 83.3 grams of Panax notoginseng.

[0027] 2. Preparation method: After the above three flavors are ultrafinely pulverized, mixed with 15g dextrin, made into granules, dried, added with 1.7g magnesium stearate, pressed into 1000 tablets, coated with sugar or film, to obtain.

[0028] 3. Properties: This product is a sugar-coated tablet or a film-coated tablet, which turns brown after removing the coating; it has a slight odor and a slightly bitter taste.

[0029] 4. Specifications: each film-coated tablet weighs 0.35 grams, sugar-coated tablets (tablet core weighs 0.35 grams)

[0030] 5. Usage and dosage: take orally. 4 tablets at a time, 3 times a day.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a dendrobium traditional Chinese medicine composition, a preparation method and application thereof. The dendrobium traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 1-2 parts of dendrobium, 1-3 parts of turtle shell and 1-2 parts of pseudo-ginseng. The preparation method comprises the following steps: respectively micro-pulverizing the raw materials to 10-60 thousand meshes, evenly mixing, and processing into an oral solid preparation. The dendrobium traditional Chinese medicine composition can be used for treating aplastic anemia, and has obvious effect. The traditional Chinese medicine composition has the effects of nourishing yin and suppressing hyperactive yang, tonifying the kidney, regenerating the marrow, promoting blood circulation and nourishing the blood, and is safe and effective. Compared with common pulverization, the preparation method disclosed by the invention can greatly enhance the absorption availability of rare medicinal herbs, and effectively reduce the dosage. Compared with a common decoction method, the preparation method disclosed by the invention can overcome the defects of high time and labor consumption and low extraction rate due to long-time decoction, effectively lower the production cost and enhance the drug effect.

Description

1. Technical field [0001] The present invention relates to a traditional Chinese medicine composition, its preparation method and its use, in particular to a dendrobium traditional Chinese medicine composition, its preparation method and its use. 2. Background technology [0002] Aplastic anemia (AA), referred to as aplastic anemia, is a serious hematopoietic system disease characterized by pancytopenia and bone marrow hematopoietic failure. In recent years, the annual incidence rate abroad is 2 / 100,000 people, and the domestic annual incidence rate is 7.4 / 100,000 people, of which acute aplastic anemia is 1.4 / 100,000 people. Increase, the incidence has a rising trend year by year. Severe aplastic anemia progresses rapidly and has a high mortality rate, with the mortality rate reaching over 90% within one year, which seriously threatens human health. The etiology of aplastic anemia is not yet fully understood, but most of them are related to known drugs, chemical substances...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P7/06A61K35/56A61K35/586
Inventor 王新生金海英李俊张炜玲谢亚凤
Owner JIUXIANZUN HUOSHAN DENDROBIUM CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products