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Compound gynura divaricata antidiabetic preparation and preparation method thereof

A white-backed notoginseng and blood sugar-lowering technology, which can be used in medical formulas, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of poor liver and kidney function, and it is not suitable to take it, so as to improve platelet function and reduce blood hyperplasia. Coagulation state, effect of improving blood lipids

Active Publication Date: 2013-07-17
江苏华生安颐生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sulfonylureas (glibenclamide) are commonly used oral hypoglycemic drugs, suitable for type II diabetics with more than 30% of pancreatic B cell function remaining, but such hypoglycemic drugs are mainly metabolized in the liver, so liver and kidney function Those with severe adverse reactions should not take it
It can be seen that the current diabetes treatment drugs have certain side effects or limitations

Method used

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  • Compound gynura divaricata antidiabetic preparation and preparation method thereof
  • Compound gynura divaricata antidiabetic preparation and preparation method thereof
  • Compound gynura divaricata antidiabetic preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Weigh 145g of Panax notoginseng, 81g of kudzu root, 90g of Gynostemma pentaphyllum and 54g of stevia respectively, after drying respectively, pass through a 1250-mesh sieve, pulverize into superfine powder, then mix evenly according to the mass ratio of 15:9:10:6, Sterilize by microwave at 80°C for 5 minutes, package and inspect the quality to obtain the compound Baibei notoginseng hypoglycemic preparation.

Embodiment 2

[0028] Example 2 Experimental Research on Hypoglycemic Effect

[0029] 1 material

[0030] 1.1 Animal Wistar male rats were purchased from Anhui Changlinhe Pharmaceutical Technology Co., Ltd.

[0031] 1.2 Drugs and reagents Tangmaikang, China Academy of Traditional Chinese Medicine; Streptozotocin (when used, prepare 1% streptozotocin solution with 0.1mol / L pH 4.2 sterile citric acid-sodium citrate buffer solution), Sigma Company; blood glucose and blood lipid determination kits, Nanjing Jiancheng Bioengineering Research Institute.

[0032] 1.3 Instruments TU1810 UV-Vis spectrophotometer, Beijing General Instrument Company; TDL-5 centrifuge, Shanghai Anting Scientific Instrument Factory; digital constant temperature water bath, Changzhou Guohua Electric Co., Ltd.

[0033] 2 methods

[0034] 2.1 Preparation of test drugs

[0035] 2.1.1 The compound Radix Notoginseng preparation of Example 1 is prepared into a suspension of 0.4 g crude drug / mL with physiological saline befor...

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Abstract

The invention provides a compound gynura divaricata antidiabetic preparation which consists of gynura divaricata, radix puerariae, gynostemma pentaphyllum and stevia rebaudiana bertoni. The compound gynura divaricata antidiabetic preparation can be used for preparing medicaments for preventing or treating diabetes mellitus, or used in the preparation of health food with the antidiabetic effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compound preparations, in particular to a compound white back notoginseng hypoglycemic preparation and a preparation method thereof. Background technique [0002] Diabetes is caused by a variety of pathogenic factors such as genetic factors, immune dysfunction, microbial infection and its toxins, and mental factors acting on the body, resulting in hypofunction of pancreatic islets, insulin resistance, etc., leading to a series of changes in sugar, protein, fat, water, and electrolytes. Metabolic disorder syndrome is clinically characterized by hyperglycemia. In typical cases, symptoms of "three excesses and one deficiency" may appear, namely polydipsia, polyphagia, polyuria and weight loss. [0003] According to the latest statistics of the International Diabetes Federation in 2009, there are 285 million diabetic patients worldwide, and more than half of them are between the ages of 20 ...

Claims

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Application Information

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IPC IPC(8): A61K36/48A61P3/10
Inventor 俞浩牛振华
Owner 江苏华生安颐生物科技有限公司
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