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Folium turpiniae ethanol percolating extract, preparation method and application thereof

A technology of percolating and extracting and Radix Radix is ​​applied in the field of ethanol percolating extract of Radix Radix et al. Effect

Active Publication Date: 2013-06-26
JIANGXI SHANXIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine "Oseltamivir Phosphate (Tamiflu, (3R, 4R, 5S)-4-Acetamide-5-Amino-3(1-Propoxyethyl)-1-Cyclohexene-1 Carboxylic Acid Ethyl Phosphate "Salt)" is a neuraminidase inhibitor, which has a specific inhibitory effect on the entry of influenza virus into cells, but it is not only expensive, but also some patients experience vomiting, nausea, insomnia, headache, abdominal pain, diarrhea, dizziness, fatigue, Side effects such as nasal congestion, sore throat, and coughing

Method used

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  • Folium turpiniae ethanol percolating extract, preparation method and application thereof
  • Folium turpiniae ethanol percolating extract, preparation method and application thereof
  • Folium turpiniae ethanol percolating extract, preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0026] Preparation method: Take the coarse powder of the round leaves of Shanxiang, use 50% ethanol as the extractant, soak it for 24 hours, then carry out percolation at a speed of 7ml / kg / min, collect 11 times the percolation liquid of the medicinal material, recover the ethanol, and depressurize Concentrate to a thick paste or dry to obtain the ethanol percolation extract of Shanxiang round leaves.

Embodiment 2

[0028] Preparation method: take the round leaf powder of Shanxiang, use 60% ethanol as the extractant, soak for 48 hours, percolate at a speed of 2ml / kg / min, collect 9 times the amount of percolation liquid of medicinal materials, recover ethanol, and depressurize Concentrate to a thick paste or dry to obtain the ethanol percolation extract of Shanxiang round leaves.

Embodiment 3

[0030] Preparation method: take the coarse powder of the round leaves of Shanxiang, use 65% ethanol as the extractant, soak for 48 hours, and percolate at a speed of 5ml / kg / min, collect 8 times the percolation liquid of the medicinal material, recover the ethanol, and depressurize Concentrate to a thick paste or dry to obtain the ethanol percolation extract of Shanxiang round leaves.

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Abstract

The invention relates to an application of a folium turpiniae ethanol percolating extract which is used for preparation of drugs capable of preventing and treating flu complication diseases. The complications refer to splenic injury and / or lung injury. The extract is obtained through the extraction of the ethanol percolation of the folium turpiniae. The extracting method includes selecting coarsepower of the folium turpiniae, adding 25%-90% of ethanol as an extractant, impregnating the coarse powder for 12-72 hours, percolating at a speed of 1-8ml / kg / minute, collecting percolate with an amount 4-9 times of the crude drug, recycling the ethanol, reducing pressure and concentrating the percolate to thick paste, or drying the percolate to obtain the folium turpiniae ethanol percolating extract.

Description

technical field [0001] The present invention relates to an ethanol percolation extract of Cymbidium saponifolium and its preparation method and application. Background technique [0002] At present, influenza virus is becoming more and more serious, and influenza virus is closely related to respiratory diseases and systemic diseases caused by it. my country is one of the countries with high incidence of influenza. Not only has a large population, but also living habits are conducive to the transmission of influenza virus. The average number of episodes ranged from 0.3 to 0.7, and 2 to 4 in key groups. Influenza poses a serious threat to human beings, especially the emerging strains of influenza virus, which not only cause secondary infections of other microorganisms, but also directly lead to organ damage and allergic reactions leading to death. But there is no effective method and treatment means for treating influenza virus and its disease (influenza) at present, such as t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P31/16A61K127/00
Inventor 唐春山张华敏王燕平谢宁吕武清杨小玲刘地发李志勇程帆
Owner JIANGXI SHANXIANG PHARMA