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A gel and matrix technology, applied in the field of intestinal medical treatment, can solve the problems of poor effect and strong irritability, and achieve the effects of long-lasting effect, small side effects and strong osmotic effect.
Active Publication Date: 2012-09-19
武汉正午阳光医药生物科技有限公司
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[0004] The invention provides a laxative gel, which aims to solve the technical problems of poo
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Embodiment 1
[0028] A kind of laxative gel, comprises matrix gel and glycerin, the mass ratio of described matrix gel and glycerol is 1: 6.5, and the raw material that described matrix gel comprises and raw material dosage are:
[0031] A kind of laxative gel, comprises matrix gel and glycerin, the mass ratio of described matrix gel and glycerol is 1: 6.5, and the raw material that described matrix gel comprises and raw material dosage are:
[0034] A kind of laxative gel, comprises matrix gel and glycerin, the mass ratio of described matrix gel and glycerol is 1: 6.5, and the raw material that described matrix gel comprises and raw material dosage are:
[0036] The following is a clinical verification of the laxative effect of the laxative gel provided in the embodiments of the present invention.
[0037] 1) Treatment method
[0038] 108 patients with constipation were randomly divided into three observation groups (28 cases) and a control group (24 cases), and the laxative effect was observed.
[0039] Control group: Oral bifidotriple live bacteria capsules (the main ingredients are Bifidobacterium longum, Lactobacillus and Enterococcus faecalis), 1 capsule each time, 3 times a day. On this basis, Kasailu w...
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Abstract
The invention is applied to the field of intestinal medical treatment and provides laxative gel. The laxative gel comprises matrix gel and glycerol, wherein the mass ratio of the matrix gel to the glycerol is (1:5)-(1:8); the matrix gel contains raw materials of carbomer, nano-silver solution, ethanol, propanediol, ammonia water, ethyl p-hydroxybenzoate, natural plant extract essential soil and purified water in the mixture ratio of 30 g:(45-75 ml):(200-260 ml):(60-100 ml):(1.3-2.7 ml):(3.2-4.8 g):(300-400 ml):(2000-3000 ml). After the laxative gel provided by the invention is injected into anorectum, the laxative gel can be uniformly distributed on the inner wall of rectum and forms a layer of water storage film, so that the inner wall of the rectum is effectively lubricated and stool issoftened and is prone to be excreted; and due to the natural water-soluble performance of the gel, no residue after use is ensured. According to the safe physical therapy principle, the curative effect is defined, the clinical requirement is better met and the durability and the intendance of general products are avoided.
Description
technical field [0001] The invention belongs to the field of intestinal medicine, in particular to a laxative gel and a preparation method thereof. Background technique [0002] With the change of people's diet structure and the influence of mental, psychological and social factors, the incidence of constipation tends to increase. The prevalence rate of constipation in the crowd is as high as 27%. Constipation can affect people of all ages. Women are more than men, and the elderly are more than young and middle-aged. Because of the high incidence of constipation and the complicated etiology, it brings a lot of inconvenience and distress to patients. [0003] There are two types of constipation products commonly used clinically, one is oral laxative products, and the other is external laxative products. Oral laxative products usually have little effect after being absorbed by the intestines; topical laxative products, represented by Kaisailu, mostly act directly on the anu...
Claims
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