Process for preparing biomedical graphene oxide paper

A graphene paper and biomedical technology, which is applied in the field of biomedical materials, can solve the problems of easy shedding of drug powder for medical value, unsuitable for large-scale production, complex process conditions, etc., and achieves good pore structure distribution suitable for large-scale production. and adsorption performance, the effect of simple process

Active Publication Date: 2013-02-13
重庆锦添翼新能源科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The main disadvantages of this method are: the process conditions are complicated, the time-consuming is too long, and the drug species compounded with graphene is single, which does not meet the requirements of large-scale production
The main disadvantages of this method are: using traditional gauze as the main body and only expanding graphite on the surface, the drug powder is easy to fall off, resulting in reduced medical value, and it is easy to bond with the skin wound and cause pain to the patient. Rich pore structure and high strength, flexibility and other advantages

Method used

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  • Process for preparing biomedical graphene oxide paper

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Experimental program
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Effect test

Embodiment 1

[0027] The concrete steps of a kind of biomedical graphene oxide paper preparation method are as follows:

[0028] (1) Ultrasonic vibration dispersion

[0029] According to the ratio of the mass (g) of graphene oxide: the mass (g) of auxiliary material: the volume (ml) ratio of solvent is 1: 0.5: 50, graphene oxide and auxiliary material are put into solvent, after stirring evenly, in ultrasonic The output frequency is below 500W, and ultrasonic vibration is dispersed for 60 minutes to obtain a dispersion mixture of graphene oxide and auxiliary materials.

[0030] Wherein: described auxiliary material is activated carbon fiber;

[0031] Described solvent is dehydrated alcohol.

[0032] (2) Solid-liquid separation

[0033] After the first step (1) was completed, adopt a vacuum filter with a 200ml polytetrafluoroethylene filter membrane to carry out solid-liquid separation of the dispersed mixed solution of graphene oxide and auxiliary material activated carbon fiber prepared...

Embodiment 2

[0037] A kind of preparation method of biomedical graphene oxide paper is the same as embodiment 1, wherein:

[0038] In step (1), the mass (g) of graphene oxide: the mass (g) of auxiliary material: the volume (ml) ratio of solvent is 1:1:100, the ultrasonic frequency is 300W, and the ultrasonic separation time is 120 minutes.

[0039] Wherein: the auxiliary material is carbon nanotube;

[0040] The solvent is deionized water.

[0041] In the (2) step, the mixed solution prepared in the (1) step is subjected to solid-liquid separation using a 300ml vacuum filter with a nylon filter membrane.

[0042] In the step (3), spray iodine uniformly on the surface of the solid residue collected in the step (2), to obtain a solid residue loaded with medicine, wherein: drying at a temperature of 80° C. for 120 minutes.

Embodiment 3

[0044] A kind of preparation method of biomedical graphene oxide paper is the same as embodiment 1, wherein:

[0045] In step (1), the mass (g) of graphene oxide: mass (g) of auxiliary materials: the volume (ml) ratio of solvent is 1:0:20, the ultrasonic frequency is 150W, and the ultrasonic separation time is 80 minutes.

[0046] Wherein: the auxiliary material is carbon nanotube;

[0047] The solvent is deionized water.

[0048] In step (2), a 100ml vacuum filter with a polytetrafluoroethylene filter membrane is used to separate the graphene oxide prepared in step (1) and the mixed solution of auxiliary materials into solid-liquid separation.

[0049] In the step (3), the surface of the solid residue collected in the step (2) is evenly sprayed with the agent Alec, wherein: drying at a temperature of 100° C. for 30 minutes.

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Abstract

The invention discloses a process for preparing biomedical graphene oxide paper and belongs to the field of biomedical materials. According to the process, a graphene oxide bought from market serves as a raw material, and a product is obtained through ultrasonic oscillating dispersion, solid-liquid separation and drug loading. The biomedical graphene oxide paper prepared by the process has the advantages of being controllable in thickness, large in specific surface area, abundant in pore structure, good in adsorptivity, strength and flexibility, free from toxicity and bacteria, free from irritation on human bodies and cohesiveness on skin wounds, environment-friendly and the like. The process is simple in technology, convenient to operate, low in production cost, beneficial to popularization and application and the like. The product prepared by the process can be widely applied to medical external application materials which are used for treating skin wounds (such as burns), promoting wound healing and the like, and the product can also be used for electrode materials of super-capacitors and environmental protection materials for adsorption, purification and the like.

Description

technical field [0001] The invention belongs to the technical field of biomedical materials, and in particular relates to a preparation method of biomedical graphene oxide paper as an external application material. Background technique [0002] Graphene refers to graphite with a carbon (C) atomic layer thickness, and carbon-carbon is composed of sp 2 Covalent linkages are in the form of hexagonal network layers, which are considered to be the basic structural units of fullerenes, carbon nanotubes, and graphite. Graphene paper is a macroscopically paper-like material composed of self-assembled graphene. It has the characteristics of high strength, light weight and excellent adsorption performance. Traditional external application materials, including gauze, bandages, etc., are still widely used in various types of wounds, although they have the characteristics of excellent water absorption and heat preservation, good heat resistance and alkali resistance. However, after th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D21H17/63D21H27/00
Inventor 李新禄王皓邓舒婷李鸿乂刘佳宋宏芳张勇来李同涛钟奇能
Owner 重庆锦添翼新能源科技有限公司
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