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Plant weight-losing and fat-reducing composite compatible to L-carnitine

A kind of technology of L-carnitine and composition, applied in the field of natural product medicine

Active Publication Date: 2013-04-24
INSITUTE OF BIOPHYSICS CHINESE ACADEMY OF SCIENCES +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no weight-loss drug with independent intellectual property rights in my country. This formula is safe and effective, with small dosage and convenient administration. It has a good prospect for further development and is expected to have important economic and social significance.

Method used

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  • Plant weight-losing and fat-reducing composite compatible to L-carnitine
  • Plant weight-losing and fat-reducing composite compatible to L-carnitine
  • Plant weight-losing and fat-reducing composite compatible to L-carnitine

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0084] The preparation procedures of the four extracts are described in detail as follows:

[0085] 1. Production process of lotus leaf extract (standard extract)

[0086] The lotus leaf raw materials are selected in July and August every year, and the selection standard is implemented in accordance with the "Pharmacopoeia of the People's Republic of China". The raw material is dried and crushed, passed through a 20-mesh sieve, and extracted with an aqueous solution of 60-90% ethanol (or 30-40% acetone). The proportion of the solvent is 10-20 times (w / w) of the mass of the crushed medicinal material particles. Reflux extraction at 70-80°C for 3 times, and combine the extracts. Upper macroporous resin column (styrene type or polyacrylate type, 20-100 mesh, purchased from Beijing Huideyi Technology Co., Ltd.), eluted with 60-90% ethanol, and the eluate was concentrated, cooled, and centrifuged. Filtration, drying and crushing, sieving, and sub-packaging to obtain the final ex...

Embodiment 1

[0095] According to the following weight ratio

[0096]

[0097] In a production workshop that meets the national requirements for the production of health care products or medicines, according to the national regulations on the production of health food and medicines, put the above components into the container in sequence, add appropriate amount of auxiliary materials or excipients, and mix for 40 minutes . Then the mixed substance is sieved with a 20-mesh sieve, and after packaging, irradiation sterilization and other processes, the preparation of weight loss health food or medicine in various dosage forms such as capsules, tablets, powders, granules and pills can be realized.

Embodiment 2

[0099] According to the following weight ratio

[0100]

[0101] In a production workshop that meets the national requirements for the production of health care products or medicines, according to the national regulations on the production of health food and medicines, put the above components into the container in sequence, add appropriate amount of auxiliary materials or excipients, and mix for 40 minutes . Then the mixed substance is sieved with a 20-mesh sieve, and after packaging, irradiation sterilization and other processes, the preparation of various solid dosage forms such as capsules, tablets, granules and pills can be realized.

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PUM

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Abstract

The invention provides an L-carnitine combination formula with weight-losing and fat-reducing efficacy and a method for screening the L-carnitine combination formula. A weight-losing and fat-reducing composite which has compatibility effect with L-carnitine is obtained by screening natural products and extracts by taking a triacylglycerol enzyme, amylopsin, fatty acid synthetase, an auxiliary enzyme B as target spots. An optimal composite formula comprises lotus leaves, folium llicis latifoliae, hawthorns, rhizoma alismatis extracts, the L-carnitine, or L-carnitine tartrate and related auxiliary materials. The weight-losing and fat-reducing composite comprises the following components respectively by weight percent (with usage amount in parts by weight): 2%-20%, 1%-15%, 5%-25%, 2%-20%, 20%-85% and 0.5%-10%. The weight-losing and fat-reducing composite provided by the invention is conductive to reducing the redundant fat inside a body and can be used for accelerating the breakdown of the fat inside the body, transforming the fat into energy and inhibiting the absorption of an organism on the fat and saccharide, thereby achieving the purposes of naturally controlling and reducing the weight.

Description

technical field [0001] The invention belongs to the field of natural product medicine. Specifically, the present invention relates to a plant weight-loss and lipid-lowering formula composition compatible with L-carnitine, and a method for screening the composition formula. The formula composition includes L-carnitine or its salts that can be used in food and medicine and pure natural plant extracts, and the pure natural plant extracts include one of the extracts of lotus leaf, kudingcha, hawthorn and Alisma. one or more species. The formula composition can be used in food additives, health food and medicine. Background technique [0002] Obesity refers to a physiological phenomenon in which the intake of calories exceeds the body's consumption and is stored in the body in the form of fat, resulting in a body weight exceeding the standard. Obesity is closely related to various diseases such as cardiovascular disease, type II diabetes, hypertension, dyslipidemia, hyperurice...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61P3/06A61P3/04A23L1/29A23L1/30C12Q1/44C12Q1/40C12Q1/25A61K31/205A23L33/00
Inventor 董先智李昭华刘翠徐进陈鹏照陈灿光
Owner INSITUTE OF BIOPHYSICS CHINESE ACADEMY OF SCIENCES
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