Preparation method of titanium foams for cancellous bone

Abstract

The invention relates to a preparation method of titanium foams for cancellous bone. The preparation method comprises the following steps of: (1) mixing raw materials, namely selecting a primary mixture which is obtained by uniformly mixing titanium powder and a pore forming agent in a grinding body, wherein the mass part ratio of the titanium powder to the pore forming agent is (42.8-48.2):(52.8-58.2); (2) carrying out one-direction pressing on the primary mixture by adopting a universal material testing machine to prepare a green pressing body, wherein the one-direction pressure is 200-250MPa, and the pressure holding time is 1 minute; and (3) putting the green pressing body into a vacuum carbon tube furnace, sintering the green pressing body for 2 hours at 1200-1300 DEG C in an argon protective atmosphere to ensure that the pore forming agent is removed, and finally cooling along with the furnace to obtain the titanium foams. According to the titanium foams prepared by using the preparation method, the Young modulus is matched with that of the cancellous bone of the human body, therefore the stress shielding phenomenon is effectively avoided, and an implant can be permanently fixed; and meanwhile, the titanium foams can be prevented from being oxidized as far as possible by adopting the argon protective atmosphere.

Description

technical field [0001] The invention relates to the technical field of foamed titanium materials, in particular to a method for preparing foamed titanium for cancellous bone. [0002] Background technique [0003] In recent years, bone defect repair materials have become one of the biomedical materials with the greatest clinical demand. Traditional bone substitute materials are dense metals or alloys, such as cobalt-nickel alloys, stainless steel, titanium-based alloys, etc. Among them, titanium and titanium alloys have been more widely used than other metal implant materials, which is mainly due to the excellent mechanical properties, excellent corrosion resistance, and superior biocompatibility of titanium and titanium alloys ( Biocompatibility refers to a property of the response of living body tissues to inactive materials). However, compared with human bone with a porous structure, titanium and titanium alloys face two problems as implant materials: (1) The Young’s m...

AI Technical Summary

Problems solved by technology

However, compared with human bone with a porous structure, titanium and titanium alloys face two problems as implant materials: (1) The Young’s modulus of titanium and titanium alloys does not match the modulus of bone, resulting in stress shielding ( The shunting phenomenon of the physiological stress of the bone by the fixing material is called the stress shielding of the bone by the fixing material); (2) The dense structure is not conducive to the growth of bone tissue, which reduces the service life of titanium and titanium alloy implant materials

For the first time, M. Bram et al. used powder metallurgy to add urea as a pore-forming agent to prepare titanium foam with a pore size of 100-2500 μm and a porosity of 60-80%, and studied the geometric structure of the pores of titanium foam. (shape and pore size distribution); afterward, people continue to use this method to manufacture titanium foam, and study the compression behavior of titanium foam with different porosity, the relationship between Young's modulus and relative density, energy absorption characteristics; the size of pore-forming agent, the addition However, there is still little research on the use of urea as a pore-forming agent to design and prepare titanium foam that meets the requirements of bone substitute materials.

Images