Preparation method of titanium foams for cancellous bone

A technology of foamed titanium and cancellous bone, which is applied in the field of foamed titanium materials, can solve the problems of reducing the service life of titanium and titanium alloy implant materials, unfavorable bone tissue growth, and few researches, so as to avoid stress shielding and realize Long-term fixation and simple operation

Inactive Publication Date: 2013-07-17
CHONGQING UNIV
View PDF1 Cites 11 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, compared with human bone with a porous structure, titanium and titanium alloys face two problems as implant materials: (1) The Young’s modulus of titanium and titanium alloys does not match the modulus of bone, resulting in stress shielding ( The shunting phenomenon of the physiological stress of the bone by the fixing material is called the stress shielding of the bone by the fixing material); (2) The dense structure is not conducive to the growth of bone tissue, which reduces the service life of titanium and titanium alloy implant materials
For the first time, M. Bram et al. used powder metallurgy to add urea as a pore-forming agent to p

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of titanium foams for cancellous bone
  • Preparation method of titanium foams for cancellous bone
  • Preparation method of titanium foams for cancellous bone

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0033] Example 1: See figure 2 , A method for preparing titanium foam for cancellous bone, including the following steps:

[0034] 1) Mixing of raw materials: select titanium powder and acicular crystal urea particles with a particle size of 225-420μm and mix to obtain a preliminary mixture, wherein the mass ratio of titanium powder and pore former is 46.6:53.4; titanium powder And the microscopic appearance of urea particles like figure 1 Shown. The titanium powder can be purchased directly from the market, and its surface and irregular shape can improve the strength of the green compact on the one hand, and promote sintering on the other hand.

[0035] 2) The preliminary mixture is unidirectionally pressed into a green compact using a 600KN universal material testing machine, and the green compact is pressed into a cylindrical shape, wherein the unidirectional pressure is 200 MPa and the pressure holding time is 1 min.

[0036] 3) The green compact is placed in a vacuum carbon ...

Example Embodiment

[0041] Example 2: A method for preparing titanium foam for cancellous bone includes the following steps:

[0042] 1) Mixing of raw materials: select titanium powder and needle-shaped crystalline urea particles with a particle size of 225-420μm and mix to obtain a preliminary mixture, wherein the mass ratio of titanium powder and pore former is 42.8:58.2;

[0043] 2) The preliminary mixture is unidirectionally pressed into a green compact using a 600KN universal material testing machine, and the green compact is pressed into a cylindrical shape, wherein the unidirectional pressure is 200 MPa and the pressure holding time is 1 min.

[0044] 3) The green compact is placed in a vacuum carbon tube furnace, sintered in an argon protective atmosphere at 1250°C for 2 hours to remove the pore former, and finally cooled with the furnace to obtain foamed titanium.

[0045] The foamed titanium prepared in Example 2 has a porosity of 74.2%, a compressive strength of 6.3 MPa, and a Young's modulus...

Example Embodiment

[0046] Example 3: A method for preparing titanium foam for cancellous bone includes the following steps:

[0047] 1) Mixing of raw materials: select titanium powder and acicular crystalline urea particles with a particle size of 225-420μm and mix to obtain a preliminary mixture. The mass ratio of titanium powder and pore former is 44.1:55.9;

[0048] 2) The preliminary mixture is unidirectionally pressed into a green compact using a 600KN universal material testing machine, and the green compact is pressed into a cylindrical shape with a unidirectional pressure of 250 MPa and a pressure holding time of 1 min.

[0049] 3) The green compact is placed in a vacuum carbon tube furnace, sintered in an argon protective atmosphere at 1300°C for 2 hours to remove the pore former, and finally cooled with the furnace to obtain foamed titanium.

[0050] The foamed titanium prepared in Example 3 has a porosity of 73.6%, a compressive strength of 8.3 MPa, and a Young's modulus of 0.25 GPa.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Granularityaaaaaaaaaa
Compressive strengthaaaaaaaaaa
Young's modulusaaaaaaaaaa
Login to view more

Abstract

The invention relates to a preparation method of titanium foams for cancellous bone. The preparation method comprises the following steps of: (1) mixing raw materials, namely selecting a primary mixture which is obtained by uniformly mixing titanium powder and a pore forming agent in a grinding body, wherein the mass part ratio of the titanium powder to the pore forming agent is (42.8-48.2):(52.8-58.2); (2) carrying out one-direction pressing on the primary mixture by adopting a universal material testing machine to prepare a green pressing body, wherein the one-direction pressure is 200-250MPa, and the pressure holding time is 1 minute; and (3) putting the green pressing body into a vacuum carbon tube furnace, sintering the green pressing body for 2 hours at 1200-1300 DEG C in an argon protective atmosphere to ensure that the pore forming agent is removed, and finally cooling along with the furnace to obtain the titanium foams. According to the titanium foams prepared by using the preparation method, the Young modulus is matched with that of the cancellous bone of the human body, therefore the stress shielding phenomenon is effectively avoided, and an implant can be permanently fixed; and meanwhile, the titanium foams can be prevented from being oxidized as far as possible by adopting the argon protective atmosphere.

Description

technical field [0001] The invention relates to the technical field of foamed titanium materials, in particular to a method for preparing foamed titanium for cancellous bone. [0002] Background technique [0003] In recent years, bone defect repair materials have become one of the biomedical materials with the greatest clinical demand. Traditional bone substitute materials are dense metals or alloys, such as cobalt-nickel alloys, stainless steel, titanium-based alloys, etc. Among them, titanium and titanium alloys have been more widely used than other metal implant materials, which is mainly due to the excellent mechanical properties, excellent corrosion resistance, and superior biocompatibility of titanium and titanium alloys ( Biocompatibility refers to a property of the response of living body tissues to inactive materials). However, compared with human bone with a porous structure, titanium and titanium alloys face two problems as implant materials: (1) The Young’s m...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C22C1/08C22C14/00
Inventor 肖健邱贵宝廖益龙白晨光吕学伟扈玫珑徐健张生富温良英张静
Owner CHONGQING UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products