Traditional Chinese medicine composite for treating headache and preparation method of traditional Chinese medicine composite
A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating headaches, can solve problems such as difficulty in controlling the quality of medicines, increase in raw material costs, rising production costs, etc., and achieve stable and controllable product quality, fast drug release, and convenient administration Effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0062] Example 1: Preparation of Tianxiong Toufeng Tablets
[0063] 1. Prescription:
[0064] Chuanxiong 750g Gastrodia elata 600g Yuanhu 600g
[0065] Angelica dahurica 300g White peony root 300g Scorpio 45g
[0066] 2, the preparation of Chinese medicine composition:
[0067] Take the medicinal materials (except scorpion) according to the prescription ratio, and decoct three times when the amount of water added is 4 times, 3 times and 3 times the weight of the medicinal materials, and decoct for 1.5 hours each time, filter, combine the filtrate, and concentrate under reduced pressure to For the liquid extract with a relative density of 1.20 (measured at 60°C), add ethanol to make the alcohol content 70%, let it stand for 24 hours, take the supernatant, recover the ethanol, concentrate under reduced pressure to a relative density of 1.30-1.35 (60°C Measure) the thick paste, dry under reduced pressure, and pulverize, pass 100 mesh sieves, get dry soaking powder. Weigh the ...
Embodiment 2
[0080] Embodiment two: the pharmacodynamic experiment of Chinese medicine composition
[0081] 【Test drug】
[0082] Test drug name: the traditional Chinese medicine composition obtained in the manner described in Example 1——Tianxiong Toufeng Tablets (hereinafter referred to as "Chinese medicinal composition" unless otherwise indicated), wherein each gram of Chinese medicinal composition is equivalent to 9.03 crude drugs.
[0083] 【Positive control drug】
[0084] Sumatriptan succinate tablets, Tianjin Huajin Pharmaceutical Co., Ltd., specification: 100mg / tablet, batch number: 2A6914T. Zhengtian Pills, China Resources Sanjiu Pharmaceutical Co., Ltd., specification: 6g / bag, batch number: 1202034H.
[0085] Ibuprofen tablets, Chongqing Kerui Pharmaceutical (Group) Co., Ltd., specification: 0.1 g / tablet, batch number: 582001. Estazolam tablets, Huazhong Pharmaceutical Co., Ltd., specification: 1mg / tablet, batch number: 20120402.
[0086] 【Experimental animals】
[0087] SD rats...
Embodiment 3
[0177] The acute toxicity experiment of embodiment three Chinese medicine compositions
[0178] The dry cream powder of traditional Chinese medicine composition is based on the maximum dosage of 4.25g crude drug / ml, 40ml / kg / time and 3 times / 24h (510.00g crude drug / kg / 24h), which is approximately equivalent to 983 times the clinical daily dose. Administer KM mice, and observe the symptoms of toxic reactions and recovery time in mice within 14 days after administration.
[0179] Results: After administration, no abnormalities were found in the motor function, reflex, eye examination indications, cardiovascular indications, saliva secretion, muscle tone, and skin of the mice in the administration group and the control group. The feces of the mice in the two groups showed Wet and granular, no toxic reactions such as convulsions, convulsions, piloerection, analgesia or death. During the experimental observation period, the average body weight growth rate and food intake of the mic...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com