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A pharmaceutical composition for clinical prevention, nursing and treatment of trichomonal vaginitis

A technology of trichomonal vaginitis and composition, which is applied in the field of medicine, can solve the problems of large toxic and side effects, ineffective effects, and easy delays in the disease, and achieve the effects of simple preparation, good therapeutic effect, and remarkable and reliable curative effect

Active Publication Date: 2016-03-16
HAIMEN CITY RUITAI TEXTILE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned treatment methods may have relatively large toxic and side effects, and are prone to relapse, or the effect is not obvious, and it is easy to delay the condition; the prior art needs a pharmaceutical composition with good therapeutic effect, low toxic and side effects, and both standard and concurrent treatments.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A pharmaceutical composition for clinical prevention, care and treatment of trichomonas vaginitis, which is prepared from the following raw materials in parts by weight:

[0019] Anemarrhena 30, Salvia 28, Honeysuckle 27, Plantain 25, Polygonum cuspidatum 25,

[0020] Angelica 23, mulberry leaf 22, catechin 22, hawthorn 20, skullcap 18,

[0021] Baibu 16, Peach Kernel 14, Phellodendron 12, Bupleurum 10, Rehmannia 10,

[0022] Gentiana 9, Campanulaceae 8, Pulsatilla 6, Cangzhu 5, Corydalis 3,

[0023] Achyranthes bidentata 2, safflower 2, Chuanxiong 1.

[0024] The preparation method of above-mentioned pharmaceutical composition comprises the steps:

[0025] Weigh each raw material according to the weight; mix each raw material evenly, add 3 times the weight of water to soak for 30 minutes, boil with strong fire, then decoct with slow fire for 1 hour, filter and collect the filtrate and filter residue; add water to the filter residue to remove The slag shall prevail,...

Embodiment 2

[0028] In vitro inhibition test against Trichomonas vaginalis

[0029] Trichomonas isolated clinically and grown well in CPLM medium after several transplants were diluted to about 6×10 5 Strips / mL (counted by hemocytometer). Adopt double dilution method, with CPLM culture medium, lotion of the present invention is mixed into series concentration, each concentration 2 tubes, inoculate above-mentioned trichomonas suspension 0.5ml (contain about 3 * 10 5 Bar) were cultured at 37°C for 48 hours, and the insect inhibition rate was obtained by counting with a hemocytometer. The results are shown in Table 1.

[0030] Table 1

[0031] Dilution

[0032] Analysis of the above results shows that the pharmaceutical composition lotion prepared in Example 1 of the present invention has obvious inhibitory effect on Trichomonas vaginalis, suggesting that the prevention and treatment effect on Trichomonas vaginalis is very significant.

Embodiment 3

[0034] The clinical therapeutic effect of the pharmaceutical composition prepared by embodiment 1:

[0035] Clinical data: A total of 120 patients were diagnosed with trichomonal vaginitis by vaginal secretion examination in "Guidelines for Clinical Research of New Drugs (Chinese Medicine) · Standards for Diagnosis and Treatment of Vaginitis", aged 21-49 years, with an average of 38 years old. They were randomly divided into two groups, 60 cases in the control group and 60 cases in the treatment group.

[0036] Treatment method: the control group used Jieeryin or Fuyanjie to flush the vagina, and after flushing, metronidazole tablets were added to the vagina, and at the same time, metronidazole tablets were taken orally 0.2g each time, 3 times a day, for 10 consecutive days; the treatment group used this medicine. Wash the vagina with the lotion prepared in Example 1 of the invention, once every morning and evening, and take 0.2 g of metronidazole tablets orally each time, 3 t...

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Abstract

The invention belongs to the field of medicines, and discloses a pharmaceutical composition for clinically preventing, nursing and treating trichomonas vaginitis. The pharmaceutical composition is prepared from the following medicines in parts by weight: 30 parts of rhizoma anemarrhenae, 28 parts of the roots of red-rooted salvia, 27 parts of honeysuckles, 25 parts of plantain herb, 25 parts of polygonum cuspidatum, 23 parts of angelica sinensis, 22 parts of folium mori, 22 parts of cutch, 20 parts of hawthorn, 18 parts of scutellaria baicalensis, 16 parts of radix stemonae, 14 parts of peach kernels, 12 parts of golden cypress, 10 parts of radix bupleurim, 10 parts of rehmannia, 9 parts of felwort, 8 parts of platycodon grandiflorum, 6 parts of the roots of Chinese pulsatilla, 5 parts of rhizoma atractylodis, 3 parts of corydalis tuber, 2 parts of radix achyranthis bidentatae, 2 parts of flowers carthami and 1 part of ligusticum wallichii. The pharmaceutical composition prepared by the invention is a pure traditional Chinese medicine which is low in toxic and side effects and good in curative effect, and can be used for clinically preventing, nursing and treating trichomonas vaginitis.

Description

technical field [0001] The invention belongs to the technical field of medicine, relates to a pharmaceutical composition for clinical prevention, care and treatment of vaginitis, in particular to a pharmaceutical composition for clinical prevention, care and treatment of trichomonal vaginitis. Background technique [0002] Vaginitis is a common and frequently-occurring disease in women's reproductive system inflammation. The main symptoms are increased vaginal discharge, itching of the vulva or burning sensation of the genitals. Trichomonal vaginitis is caused by Trichomonas, which parasitize the human body, including Trichomonas vaginalis, Trichomonas hominis and Oral Trichomonas, which parasitize the genitourinary system, intestinal tract and oral cavity respectively, and are related to skin diseases The most common is Trichomonas vaginalis, which causes Trichomonas vaginitis. It is a parasitic disease that is mainly transmitted through sexual intercourse and is contagiou...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/904A61P15/02A61P33/02
Inventor 孙运芳
Owner HAIMEN CITY RUITAI TEXTILE TECH CO LTD
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